GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID ▲	GO Labels	GO IDs
GL_000779	Myelin-associated glycoprotein	P20916	Homo sapiens	9606	Schmidt-Lanterman incisure axon regeneration carbohydrate binding cell adhesion cell-cell adhesion via plasma-membrane adhesion molecules cellular response to mechanical stimulus central nervous system myelin formation compact myelin ganglioside GT1b binding membrane raft mesaxon myelin sheath myelin sheath adaxonal region negative regulation of axon extension negative regulation of neuron apoptotic process negative regulation of neuron differentiation negative regulation of neuron projection development paranode region of axon plasma membrane positive regulation of astrocyte differentiation positive regulation of myelination protein homodimerization activity protein kinase binding sialic acid binding signaling receptor binding substantia nigra development transmission of nerve impulse	GO:0005102 GO:0005886 GO:0007155 GO:0010977 GO:0019226 GO:0019901 GO:0021762 GO:0030246 GO:0030517 GO:0031103 GO:0031643 GO:0032289 GO:0033270 GO:0033691 GO:0035749 GO:0042803 GO:0043209 GO:0043218 GO:0043220 GO:0043524 GO:0045121 GO:0045665 GO:0048711 GO:0071260 GO:0097453 GO:0098742 GO:1905576
GL_001379	BOS complex subunit NOMO3	P69849	Homo sapiens	9606	carbohydrate binding determination of left/right asymmetry in lateral mesoderm endoplasmic reticulum membrane multi-pass translocon complex multi-pass transmembrane protein insertion into ER membrane negative regulation of nodal signaling pathway ribosome binding	GO:0003140 GO:0005789 GO:0030246 GO:0043022 GO:0160063 GO:0160064 GO:1900108
GL_000102	Beta/gamma crystallin domain-containing protein 1	Q9Y4K1	Homo sapiens	9606	carbohydrate binding	GO:0030246
GL_001725	Neutral alpha-glucosidase AB	Q14697	Homo sapiens	9606	Golgi apparatus N-glycan processing RNA binding alpha-glucosidase activity carbohydrate binding carbohydrate metabolic process endoplasmic reticulum lumen extracellular exosome glucan 1,3-alpha-glucosidase activity glucosidase II complex intracellular membrane-bounded organelle melanosome membrane	GO:0003723 GO:0005788 GO:0005794 GO:0005975 GO:0006491 GO:0016020 GO:0017177 GO:0030246 GO:0033919 GO:0042470 GO:0043231 GO:0070062 GO:0090599
GL_000631	Killer cell lectin-like receptor subfamily G member 2	A4D1S0	Homo sapiens	9606	carbohydrate binding membrane	GO:0016020 GO:0030246
GL_000199	C-type lectin domain family 9 member A	Q6UXN8	Homo sapiens	9606	carbohydrate binding cell surface membrane positive regulation of cytokine production receptor-mediated endocytosis	GO:0001819 GO:0006898 GO:0009986 GO:0016020 GO:0030246
GL_000925	Polypeptide N-acetylgalactosaminyltransferase 5	Q7Z7M9	Homo sapiens	9606	Golgi apparatus Golgi membrane O-glycan processing carbohydrate binding glycosaminoglycan biosynthetic process metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation	GO:0000139 GO:0004653 GO:0005794 GO:0006024 GO:0006493 GO:0016266 GO:0030246 GO:0046872
GL_000766	Low affinity immunoglobulin epsilon Fc receptor	P06734	Homo sapiens	9606	B cell antigen processing and presentation Fc receptor-mediated immune complex endocytosis IgE binding carbohydrate binding external side of plasma membrane extracellular exosome immune response integrin binding low-affinity IgE receptor activity macrophage activation metal ion binding plasma membrane positive regulation of humoral immune response mediated by circulating immunoglobulin positive regulation of killing of cells of another organism positive regulation of nitric-oxide synthase activity positive regulation of nitric-oxide synthase biosynthetic process	GO:0002450 GO:0002925 GO:0005178 GO:0005886 GO:0006955 GO:0009897 GO:0019769 GO:0019863 GO:0030246 GO:0042116 GO:0046872 GO:0051000 GO:0051712 GO:0051770 GO:0070062 GO:0160006
GL_000551	Inactive cell surface hyaluronidase CEMIP2	Q9UHN6	Homo sapiens	9606	angiogenesis cadherin binding calcium ion binding carbohydrate binding cytosol extracellular exosome hyaluronan catabolic process intracellular membrane-bounded organelle membrane nucleolus plasma membrane regulation of sprouting angiogenesis	GO:0001525 GO:0005509 GO:0005730 GO:0005829 GO:0005886 GO:0016020 GO:0030214 GO:0030246 GO:0043231 GO:0045296 GO:0070062 GO:1903670
GL_000309	Chitinase-3-like protein 1	P36222	Homo sapiens	9606	activation of NF-kappaB-inducing kinase activity apoptotic process carbohydrate binding carbohydrate metabolic process cartilage development cellular response to tumor necrosis factor chitin binding chitin catabolic process cytoplasm endoplasmic reticulum extracellular exosome extracellular matrix extracellular matrix structural constituent extracellular region extracellular space inflammatory response lung development perinuclear region of cytoplasm positive regulation of ERK1 and ERK2 cascade positive regulation of angiogenesis positive regulation of interleukin-8 production positive regulation of peptidyl-threonine phosphorylation positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction response to interleukin-1 response to interleukin-6 response to mechanical stimulus response to tumor necrosis factor specific granule lumen	GO:0005201 GO:0005576 GO:0005615 GO:0005737 GO:0005783 GO:0005975 GO:0006032 GO:0006915 GO:0006954 GO:0007250 GO:0008061 GO:0009612 GO:0010800 GO:0030246 GO:0030324 GO:0031012 GO:0032757 GO:0034612 GO:0035580 GO:0045766 GO:0048471 GO:0051216 GO:0051897 GO:0070062 GO:0070374 GO:0070555 GO:0070741 GO:0071356