GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID ▼	GO Labels	GO IDs
GL_000910	Polypeptide N-acetylgalactosaminyltransferase 2	Q6PB93	Mus musculus	10090	Golgi apparatus Golgi cisterna membrane Golgi lumen Golgi stack O-glycan processing carbohydrate binding extracellular region manganese ion binding perinuclear region of cytoplasm polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation protein O-linked glycosylation via serine protein O-linked glycosylation via threonine protein maturation	GO:0004653 GO:0005576 GO:0005794 GO:0005795 GO:0005796 GO:0006493 GO:0016266 GO:0018242 GO:0018243 GO:0030145 GO:0030246 GO:0032580 GO:0048471 GO:0051604
GL_002007	E-selectin	Q00690	Mus musculus	10090	actin filament-based process calcium ion binding caveola clathrin-coated pit cortical cytoskeleton external side of plasma membrane extracellular space heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules leukocyte cell-cell adhesion leukocyte migration leukocyte tethering or rolling membrane raft oligosaccharide binding perinuclear region of cytoplasm phospholipase binding plasma membrane positive regulation of leukocyte migration positive regulation of leukocyte tethering or rolling positive regulation of receptor internalization response to cytokine response to interleukin-1 sialic acid binding transmembrane signaling receptor activity	GO:0002092 GO:0002687 GO:0004888 GO:0005509 GO:0005615 GO:0005886 GO:0005901 GO:0005905 GO:0007157 GO:0007159 GO:0009897 GO:0030029 GO:0030863 GO:0033691 GO:0034097 GO:0043274 GO:0045121 GO:0048471 GO:0050900 GO:0050901 GO:0070492 GO:0070555 GO:1903238
GL_000836	Oxidized low-density lipoprotein receptor 1	Q9EQ09	Mus musculus	10090	carbohydrate binding extracellular region extrinsic component of plasma membrane identical protein binding immune system process inflammatory response intracellular membrane-bounded organelle leukocyte cell-cell adhesion lipoprotein metabolic process low-density lipoprotein particle receptor activity membrane raft negative regulation of gene expression nucleoplasm plasma membrane receptor complex	GO:0002376 GO:0005041 GO:0005576 GO:0005654 GO:0005886 GO:0006954 GO:0007159 GO:0010629 GO:0019897 GO:0030246 GO:0042157 GO:0042802 GO:0043231 GO:0043235 GO:0045121
GL_000616	Killer cell lectin-like receptor subfamily B member 1B allele A	P27812	Mus musculus	10090	carbohydrate binding cell surface external side of plasma membrane identical protein binding negative regulation of natural killer cell mediated cytotoxicity plasma membrane regulation of natural killer cell mediated cytotoxicity signaling receptor activity	GO:0005886 GO:0009897 GO:0009986 GO:0030246 GO:0038023 GO:0042269 GO:0042802 GO:0045953
GL_000134	C-type lectin domain family 1 member A	Q8BWY2	Mus musculus	10090	carbohydrate binding membrane signal transduction transmembrane signaling receptor activity	GO:0004888 GO:0007165 GO:0016020 GO:0030246
GL_000184	C-type lectin domain family 4 member F	P70194	Mus musculus	10090	NK T cell activation carbohydrate binding endocytosis external side of plasma membrane galactose binding glycolipid binding plasma membrane	GO:0005534 GO:0005886 GO:0006897 GO:0009897 GO:0030246 GO:0051132 GO:0051861
GL_001412	Complement C4-B	P01029	Mus musculus	10090	axon carbohydrate binding complement activation complement activation, classical pathway complement binding complement component C1q complex binding dendrite endopeptidase inhibitor activity extracellular region extracellular space immunoglobulin mediated immune response inflammatory response innate immune response neuronal cell body symbiont cell surface synapse	GO:0001848 GO:0001849 GO:0004866 GO:0005576 GO:0005615 GO:0006954 GO:0006956 GO:0006958 GO:0016064 GO:0030246 GO:0030424 GO:0030425 GO:0043025 GO:0045087 GO:0045202 GO:0106139
GL_000072	Attractin	Q9WU60	Mus musculus	10090	carbohydrate binding cerebellum development chromatin binding cytoplasm extracellular space inflammatory response myelination pigmentation plasma membrane regulation of multicellular organism growth response to oxidative stress signaling receptor activity	GO:0003682 GO:0005615 GO:0005737 GO:0005886 GO:0006954 GO:0006979 GO:0021549 GO:0030246 GO:0038023 GO:0040014 GO:0042552 GO:0043473
GL_000499	Galectin-4	Q8K419	Mus musculus	10090	antibacterial peptide biosynthetic process carbohydrate binding collagen-containing extracellular matrix defense response to bacterium extracellular space galactoside binding	GO:0002780 GO:0005615 GO:0016936 GO:0030246 GO:0042742 GO:0062023
GL_002394	Laminin subunit alpha-2	Q60675	Mus musculus	10090	Schwann cell differentiation animal organ morphogenesis axon guidance basement membrane cell adhesion collagen-containing extracellular matrix dendritic spine extracellular matrix structural constituent extracellular region neuromuscular junction positive regulation of cell adhesion positive regulation of integrin-mediated signaling pathway positive regulation of muscle cell differentiation positive regulation of synaptic transmission, cholinergic protein complex involved in cell-matrix adhesion regulation of basement membrane organization regulation of cell migration regulation of embryonic development sarcolemma signaling receptor binding synaptic cleft tissue development	GO:0005102 GO:0005201 GO:0005576 GO:0005604 GO:0007155 GO:0007411 GO:0009887 GO:0009888 GO:0014037 GO:0030334 GO:0031594 GO:0032224 GO:0042383 GO:0043083 GO:0043197 GO:0045785 GO:0045995 GO:0051149 GO:0062023 GO:0098637 GO:0110011 GO:2001046