GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin ▼	Lectin Name	UniProt ID	Species	Taxonomy ID	GO Labels	GO IDs
GL_000203	C-type lectin domain-containing protein 160	P34393	Caenorhabditis elegans	6239	carbohydrate binding extracellular region	GO:0005576 GO:0030246
GL_000202	C-type lectin domain-containing protein 1 (Fragment)	P86533	Daboia russelii	8707	carbohydrate binding extracellular region	GO:0005576 GO:0030246
GL_000201	C-type lectin domain family 9 member A	D4AD02	Rattus norvegicus	10116	carbohydrate binding cell surface membrane positive regulation of cytokine production receptor-mediated endocytosis	GO:0001819 GO:0006898 GO:0009986 GO:0016020 GO:0030246
GL_000200	C-type lectin domain family 9 member A	Q8BRU4	Mus musculus	10090	carbohydrate binding cell surface membrane positive regulation of cytokine production receptor-mediated endocytosis	GO:0001819 GO:0006898 GO:0009986 GO:0016020 GO:0030246
GL_000199	C-type lectin domain family 9 member A	Q6UXN8	Homo sapiens	9606	carbohydrate binding cell surface membrane positive regulation of cytokine production receptor-mediated endocytosis	GO:0001819 GO:0006898 GO:0009986 GO:0016020 GO:0030246
GL_000198	C-type lectin domain family 7 member A	Q6QLQ4	Mus musculus	10090	(1->3)-beta-D-glucan binding (1->3)-beta-D-glucan immune receptor activity antifungal innate immune response carbohydrate binding cell activation cell recognition cell surface cell surface pattern recognition receptor signaling pathway cell-cell adhesion cellular response to molecule of fungal origin cytoplasm detection of fungus detection of molecule of fungal origin detection of yeast external side of plasma membrane identical protein binding inflammatory response innate immune response leukocyte activation involved in immune response metal ion binding opsonin binding pattern recognition receptor activity phagocytosis, engulfment phagocytosis, recognition plasma membrane polysaccharide binding positive regulation of DNA-binding transcription factor activity positive regulation of NF-kappaB transcription factor activity positive regulation of T-helper 17 type immune response positive regulation of calcium-mediated signaling positive regulation of canonical NF-kappaB signal transduction positive regulation of cell maturation positive regulation of cell migration positive regulation of cell population proliferation positive regulation of cytokine production involved in immune response positive regulation of cytokine production involved in inflammatory response positive regulation of dendritic cell cytokine production positive regulation of gene expression positive regulation of interleukin-1 beta production positive regulation of interleukin-10 production positive regulation of interleukin-12 production positive regulation of interleukin-2 production positive regulation of interleukin-23 production positive regulation of interleukin-6 production positive regulation of interleukin-8 production positive regulation of killing of cells of another organism positive regulation of lymphocyte activation positive regulation of monocyte chemotactic protein-1 production positive regulation of nitric oxide biosynthetic process positive regulation of peptidyl-tyrosine phosphorylation positive regulation of phagocytosis positive regulation of protein-containing complex assembly positive regulation of respiratory burst positive regulation of stress-activated MAPK cascade positive regulation of superoxide anion generation positive regulation of tumor necrosis factor production positive regulation of type II interferon production positive regulation of wound healing regulation of calcineurin-NFAT signaling cascade regulation of canonical NF-kappaB signal transduction response to molecule of fungal origin response to yeast stimulatory C-type lectin receptor signaling pathway	GO:0001775 GO:0001846 GO:0001872 GO:0001874 GO:0001878 GO:0001879 GO:0002223 GO:0002238 GO:0002366 GO:0002720 GO:0002732 GO:0002752 GO:0005737 GO:0005886 GO:0006910 GO:0006911 GO:0006954 GO:0008037 GO:0008284 GO:0009897 GO:0009986 GO:0010628 GO:0016046 GO:0030246 GO:0030247 GO:0030335 GO:0031334 GO:0032491 GO:0032729 GO:0032731 GO:0032733 GO:0032735 GO:0032743 GO:0032747 GO:0032755 GO:0032757 GO:0032760 GO:0032874 GO:0032930 GO:0038187 GO:0042802 GO:0043122 GO:0043123 GO:0045087 GO:0045429 GO:0046872 GO:0050731 GO:0050766 GO:0050850 GO:0051091 GO:0051092 GO:0051251 GO:0051712 GO:0060267 GO:0061760 GO:0070884 GO:0071226 GO:0071639 GO:0090303 GO:0098609 GO:1900017 GO:1903431 GO:2000318
GL_000197	C-type lectin domain family 7 member A	Q9BXN2	Homo sapiens	9606	(1->3)-beta-D-glucan binding MHC protein binding T cell activation antifungal innate immune response carbohydrate binding carbohydrate mediated signaling cell activation cell recognition cell surface cellular response to molecule of fungal origin cytoplasm defense response to protozoan detection of fungus detection of molecule of fungal origin detection of yeast identical protein binding inflammatory response membrane metal ion binding pattern recognition receptor activity phagocytosis, recognition plasma membrane positive regulation of DNA-binding transcription factor activity positive regulation of NF-kappaB transcription factor activity positive regulation of T-helper 17 type immune response positive regulation of calcium-mediated signaling positive regulation of canonical NF-kappaB signal transduction positive regulation of cell maturation positive regulation of cell migration positive regulation of cell population proliferation positive regulation of cysteine-type endopeptidase activity involved in apoptotic process positive regulation of cytokine production involved in inflammatory response positive regulation of dendritic cell cytokine production positive regulation of gene expression positive regulation of interleukin-1 beta production positive regulation of interleukin-10 production positive regulation of interleukin-12 production positive regulation of interleukin-2 production positive regulation of interleukin-23 production positive regulation of interleukin-6 production positive regulation of interleukin-8 production positive regulation of killing of cells of another organism positive regulation of lymphocyte activation positive regulation of monocyte chemotactic protein-1 production positive regulation of nitric oxide biosynthetic process positive regulation of phagocytosis positive regulation of protein-containing complex assembly positive regulation of respiratory burst positive regulation of superoxide anion generation positive regulation of tumor necrosis factor production positive regulation of type II interferon production positive regulation of wound healing regulation of calcineurin-NFAT signaling cascade regulation of canonical NF-kappaB signal transduction response to yeast stimulatory C-type lectin receptor signaling pathway	GO:0001775 GO:0001872 GO:0001878 GO:0001879 GO:0002223 GO:0002732 GO:0005737 GO:0005886 GO:0006910 GO:0006954 GO:0008037 GO:0008284 GO:0009756 GO:0009986 GO:0010628 GO:0016020 GO:0016046 GO:0030246 GO:0030335 GO:0031334 GO:0032491 GO:0032729 GO:0032731 GO:0032733 GO:0032735 GO:0032743 GO:0032747 GO:0032755 GO:0032757 GO:0032760 GO:0032930 GO:0038187 GO:0042110 GO:0042287 GO:0042802 GO:0042832 GO:0043122 GO:0043123 GO:0043280 GO:0045429 GO:0046872 GO:0050766 GO:0050850 GO:0051091 GO:0051092 GO:0051251 GO:0051712 GO:0060267 GO:0061760 GO:0070884 GO:0071226 GO:0071639 GO:0090303 GO:1900017 GO:1903431 GO:2000318
GL_000196	C-type lectin domain family 6 member A	D3ZWT9	Rattus norvegicus	10116	adaptive immune response antifungal innate immune response calcium ion binding carbohydrate binding defense response to fungus external side of plasma membrane innate immune response mannose binding pattern recognition receptor activity plasma membrane positive regulation of T-helper 17 type immune response positive regulation of canonical NF-kappaB signal transduction positive regulation of cytokine production	GO:0001819 GO:0002250 GO:0005509 GO:0005537 GO:0005886 GO:0009897 GO:0030246 GO:0038187 GO:0043123 GO:0045087 GO:0050832 GO:0061760 GO:2000318
GL_000195	C-type lectin domain family 6 member A	Q6EIG7	Homo sapiens	9606	adaptive immune response antifungal innate immune response calcium ion binding carbohydrate binding defense response to fungus detection of yeast external side of plasma membrane innate immune response mannose binding pattern recognition receptor activity phospholipase binding plasma membrane positive regulation of T-helper 17 type immune response positive regulation of canonical NF-kappaB signal transduction positive regulation of cytokine production positive regulation of intracellular signal transduction positive regulation of peptidyl-tyrosine phosphorylation response to yeast stimulatory C-type lectin receptor signaling pathway	GO:0001819 GO:0001878 GO:0001879 GO:0002223 GO:0002250 GO:0005509 GO:0005537 GO:0005886 GO:0009897 GO:0030246 GO:0038187 GO:0043123 GO:0043274 GO:0045087 GO:0050731 GO:0050832 GO:0061760 GO:1902533 GO:2000318
GL_000194	C-type lectin domain family 6 member A	Q3LUH2	Bos taurus	9913	adaptive immune response antifungal innate immune response calcium ion binding carbohydrate binding defense response to fungus external side of plasma membrane innate immune response mannose binding pattern recognition receptor activity plasma membrane positive regulation of T-helper 17 type immune response positive regulation of canonical NF-kappaB signal transduction positive regulation of cytokine production	GO:0001819 GO:0002250 GO:0005509 GO:0005537 GO:0005886 GO:0009897 GO:0030246 GO:0038187 GO:0043123 GO:0045087 GO:0050832 GO:0061760 GO:2000318