GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID ▲	GO Labels	GO IDs
GL_002410	Paired immunoglobulin-like type 2 receptor beta	Q9UKJ0	Homo sapiens	9606	MHC class I protein binding activation of transmembrane receptor protein tyrosine kinase activity plasma membrane transmembrane receptor protein tyrosine kinase signaling pathway	GO:0005886 GO:0007169 GO:0007171 GO:0042288
GL_002341	Mannose-binding protein C	P11226	Homo sapiens	9606	acute-phase response antiviral innate immune response calcium-dependent protein binding cell surface cell surface pattern recognition receptor signaling pathway collagen trimer complement activation, classical pathway complement activation, lectin pathway defense response to Gram-positive bacterium defense response to bacterium external side of plasma membrane extracellular region extracellular space identical protein binding innate immune response killing by host of symbiont cells mannose binding multivesicular body negative regulation of viral process opsonization positive regulation of opsonization positive regulation of phagocytosis proteolysis response to oxidative stress serine-type endopeptidase complex signaling receptor binding surfactant homeostasis	GO:0001867 GO:0002752 GO:0005102 GO:0005537 GO:0005576 GO:0005581 GO:0005615 GO:0005771 GO:0006508 GO:0006953 GO:0006958 GO:0006979 GO:0008228 GO:0009897 GO:0009986 GO:0042742 GO:0042802 GO:0043129 GO:0045087 GO:0048306 GO:0048525 GO:0050766 GO:0050830 GO:0051873 GO:0140374 GO:1903028 GO:1905370
GL_002405	Chitinase domain-containing protein 1	Q9BWS9	Homo sapiens	9606	carbohydrate metabolic process chitin binding endomembrane system extracellular exosome extracellular region extracellular space innate immune response late endosome lysosomal lumen lysosome membrane negative regulation of cytokine production involved in inflammatory response nucleus oligosaccharide binding trans-Golgi network	GO:0005576 GO:0005615 GO:0005634 GO:0005764 GO:0005770 GO:0005802 GO:0005975 GO:0008061 GO:0012505 GO:0016020 GO:0043202 GO:0045087 GO:0070062 GO:0070492 GO:1900016
GL_000888	Polypeptide N-acetylgalactosaminyltransferase 10	Q86SR1	Homo sapiens	9606	Golgi apparatus Golgi membrane O-glycan processing carbohydrate binding metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation	GO:0000139 GO:0004653 GO:0005794 GO:0006493 GO:0016266 GO:0030246 GO:0046872
GL_000353	Doublecortin domain-containing protein 1	M0R2J8	Homo sapiens	9606	Flemming body carbohydrate binding cell cycle cell division cytoplasm intracellular signal transduction microtubule microtubule binding midbody mitotic spindle regulation of mitotic cytokinesis	GO:0005737 GO:0005874 GO:0007049 GO:0008017 GO:0030246 GO:0030496 GO:0035556 GO:0051301 GO:0072686 GO:0090543 GO:1902412
GL_001410	Collagen alpha-1(IX) chain	P20849	Homo sapiens	9606	animal organ morphogenesis carbohydrate binding collagen type IX trimer collagen-containing extracellular matrix endoplasmic reticulum lumen extracellular matrix organization extracellular matrix structural constituent conferring tensile strength extracellular region extracellular space metal ion binding protein homodimerization activity	GO:0005576 GO:0005594 GO:0005615 GO:0005788 GO:0009887 GO:0030020 GO:0030198 GO:0030246 GO:0042803 GO:0046872 GO:0062023
GL_000320	Chondrolectin	Q9H9P2	Homo sapiens	9606	carbohydrate binding centrosome cytoplasm cytosol endoplasmic reticulum membrane muscle organ development nervous system development perinuclear region of cytoplasm positive regulation of axonogenesis	GO:0005737 GO:0005789 GO:0005813 GO:0005829 GO:0007399 GO:0007517 GO:0030246 GO:0048471 GO:0050772
GL_001703	Malectin	Q14165	Homo sapiens	9606	carbohydrate binding carbohydrate metabolic process endoplasmic reticulum endoplasmic reticulum membrane enzyme binding membrane oligosaccharyltransferase complex plasma membrane protein N-linked glycosylation specific granule membrane	GO:0005783 GO:0005789 GO:0005886 GO:0005975 GO:0006487 GO:0008250 GO:0016020 GO:0019899 GO:0030246 GO:0035579
GL_000397	FRAS1-related extracellular matrix protein 1	Q5H8C1	Homo sapiens	9606	anatomical structure morphogenesis basement membrane carbohydrate binding cell communication cell-matrix adhesion collagen-containing extracellular matrix craniofacial suture morphogenesis extracellular region membrane metal ion binding	GO:0005576 GO:0005604 GO:0007154 GO:0007160 GO:0009653 GO:0016020 GO:0030246 GO:0046872 GO:0062023 GO:0097094
GL_000919	Polypeptide N-acetylgalactosaminyltransferase 4	Q8N4A0	Homo sapiens	9606	Golgi membrane O-glycan processing carbohydrate binding extracellular exosome manganese ion binding perinuclear region of cytoplasm polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation protein O-linked glycosylation via serine protein O-linked glycosylation via threonine	GO:0000139 GO:0004653 GO:0006493 GO:0016266 GO:0018242 GO:0018243 GO:0030145 GO:0030246 GO:0048471 GO:0070062