GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID ▼	GO Labels	GO IDs
GL_001104	Serum amyloid P-component	P12246	Mus musculus	10090	calcium ion binding carbohydrate binding complement component C1q complex binding extracellular space identical protein binding innate immune response negative regulation by host of viral exo-alpha-sialidase activity negative regulation by host of viral glycoprotein metabolic process negative regulation of glycoprotein metabolic process negative regulation of monocyte differentiation negative regulation of viral entry into host cell negative regulation of viral process protein-containing complex protein-containing complex assembly virion binding	GO:0001849 GO:0005509 GO:0005615 GO:0030246 GO:0032991 GO:0042802 GO:0044869 GO:0044871 GO:0045087 GO:0045656 GO:0046597 GO:0046790 GO:0048525 GO:0065003 GO:1903019
GL_000535	Grifin	Q9D1U0	Mus musculus	10090	carbohydrate binding	GO:0030246
GL_000605	Killer cell lectin-like receptor 4	Q60651	Mus musculus	10090	carbohydrate binding cell adhesion cell surface external side of plasma membrane plasma membrane	GO:0005886 GO:0007155 GO:0009897 GO:0009986 GO:0030246
GL_001742	Pleiotrophin	P63089	Mus musculus	10090	Schaffer collateral - CA1 synapse basement membrane bone mineralization carbohydrate binding cell surface chondroitin sulfate binding chondroitin sulfate proteoglycan binding decidualization dendrite arborization dendrite regeneration endoplasmic reticulum estrous cycle extracellular matrix extracellular region extracellular space glycosaminoglycan binding growth factor activity heparan sulfate binding heparin binding integrin binding integrin-mediated signaling pathway learning leukocyte chemotaxis involved in inflammatory response memory modulation of chemical synaptic transmission molecular function activator activity negative regulation of angiogenesis negative regulation of cell migration negative regulation of epithelial cell proliferation negative regulation of glial cell proliferation negative regulation of long-term synaptic potentiation negative regulation of membrane potential negative regulation of mesenchymal cell proliferation negative regulation of neuroblast proliferation negative regulation of neuromuscular junction development neuromuscular junction oogenesis ossification ossification involved in bone remodeling perinuclear region of cytoplasm plasma membrane positive regulation of apoptotic process positive regulation of axon regeneration positive regulation of bone mineralization positive regulation of cell differentiation positive regulation of cell division positive regulation of cell population proliferation positive regulation of cell-substrate adhesion positive regulation of dendrite development positive regulation of hepatocyte proliferation positive regulation of leukocyte chemotaxis positive regulation of neuron projection development positive regulation of oligodendrocyte differentiation positive regulation of ossification positive regulation of skeletal muscle acetylcholine-gated channel clustering positive regulation of stem cell differentiation postsynapse presynapse protein kinase binding protein phosphatase inhibitor activity protein-containing complex proteoglycan binding receptor clustering regulation of cell shape regulation of endothelial cell migration regulation of hemopoiesis regulation of myelination regulation of stem cell population maintenance regulation of synaptic plasticity response to auditory stimulus retinal rod cell differentiation syndecan binding tissue regeneration vascular endothelial growth factor binding	GO:0001503 GO:0002232 GO:0002690 GO:0004864 GO:0005178 GO:0005539 GO:0005576 GO:0005604 GO:0005615 GO:0005783 GO:0005886 GO:0007229 GO:0007406 GO:0007612 GO:0007613 GO:0008083 GO:0008201 GO:0008284 GO:0008360 GO:0009986 GO:0010594 GO:0010811 GO:0010976 GO:0010996 GO:0016525 GO:0019901 GO:0030246 GO:0030282 GO:0030336 GO:0030501 GO:0031012 GO:0031104 GO:0031594 GO:0031641 GO:0032991 GO:0035373 GO:0035374 GO:0038085 GO:0042246 GO:0043065 GO:0043113 GO:0043394 GO:0043932 GO:0044849 GO:0045545 GO:0045597 GO:0045778 GO:0045837 GO:0046697 GO:0048167 GO:0048471 GO:0048477 GO:0048680 GO:0048714 GO:0050680 GO:0050804 GO:0051781 GO:0060221 GO:0060253 GO:0072201 GO:0098685 GO:0098793 GO:0098794 GO:0140059 GO:0140677 GO:1900006 GO:1900272 GO:1903706 GO:1904395 GO:1904397 GO:1904399 GO:2000036 GO:2000347 GO:2000738
GL_001780	Protein AMBP	Q07456	Mus musculus	10090	IgA binding antioxidant activity carbohydrate binding cell surface cellular oxidant detoxification cellular response to reactive oxygen species chondroitin sulfate binding collagen fibril binding collagen-containing extracellular matrix cytochrome c metabolic process cytosol endoplasmic reticulum extracellular space heme binding hemoglobin metabolic process mitochondrial inner membrane nuclear membrane oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor plasma membrane protein catabolic process protein homodimerization activity protein maturation serine-type endopeptidase inhibitor activity	GO:0004867 GO:0005615 GO:0005743 GO:0005783 GO:0005829 GO:0005886 GO:0009986 GO:0016209 GO:0016653 GO:0019862 GO:0020027 GO:0020037 GO:0030163 GO:0030246 GO:0031965 GO:0034614 GO:0035374 GO:0042803 GO:0051604 GO:0062023 GO:0098633 GO:0098869 GO:1903606
GL_000163	C-type lectin domain family 2 member G	Q9D676	Mus musculus	10090	carbohydrate binding cell surface endoplasmic reticulum external side of plasma membrane extracellular space natural killer cell lectin-like receptor binding negative regulation of osteoclast differentiation	GO:0005615 GO:0005783 GO:0009897 GO:0009986 GO:0030246 GO:0045671 GO:0046703
GL_001409	Collagen alpha-1(IX) chain	Q05722	Mus musculus	10090	bone morphogenesis carbohydrate binding cartilage development chondrocyte proliferation collagen type IX trimer collagen-containing extracellular matrix extracellular matrix organization extracellular matrix structural constituent conferring tensile strength extracellular space growth plate cartilage development metal ion binding protein homodimerization activity skeletal system development tissue homeostasis	GO:0001501 GO:0001894 GO:0003417 GO:0005594 GO:0005615 GO:0030020 GO:0030198 GO:0030246 GO:0035988 GO:0042803 GO:0046872 GO:0051216 GO:0060349 GO:0062023
GL_001168	Versican core protein	Q62059	Mus musculus	10090	calcium ion binding carbohydrate binding cell adhesion cell surface central nervous system development collagen-containing extracellular matrix extracellular matrix extracellular region extracellular space glial cell differentiation glial cell migration heart development hyaluronic acid binding interphotoreceptor matrix perineuronal net photoreceptor outer segment positive regulation of neuroblast proliferation protein phosphatase binding regulation of phosphoprotein phosphatase activity skeletal system development synapse ureteric bud development	GO:0001501 GO:0001657 GO:0001750 GO:0002052 GO:0005509 GO:0005540 GO:0005576 GO:0005615 GO:0007155 GO:0007417 GO:0007507 GO:0008347 GO:0009986 GO:0010001 GO:0019903 GO:0030246 GO:0031012 GO:0033165 GO:0043666 GO:0045202 GO:0062023 GO:0072534
GL_001834	Signal transducer CD24	P24807	Mus musculus	10090	B cell apoptotic process B cell proliferation B cell receptor transport into membrane raft CD4-positive, alpha-beta T cell proliferation Hsp70 protein binding Hsp90 protein binding T cell costimulation T cell homeostatic proliferation apoptotic mitochondrial changes apoptotic nuclear changes apoptotic signaling pathway calcium-mediated signaling carbohydrate binding cell activation cell migration cell surface cell surface receptor signaling pathway chemokine receptor transport out of membrane raft cholesterol homeostasis ciliary membrane external side of plasma membrane glomerular parietal epithelial cell differentiation heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules homotypic cell-cell adhesion innate immune response integrin activation intracellular membrane-bounded organelle leukocyte cell-cell adhesion leukocyte migration involved in inflammatory response membrane membrane raft microvillus membrane motile cilium negative regulation of B cell proliferation negative regulation of T cell homeostatic proliferation negative regulation of erythrocyte aggregation negative regulation of erythrocyte clearance negative regulation of inflammatory response to wounding negative regulation of interleukin-6 production negative regulation of monocyte chemotactic protein-1 production negative regulation of neuroblast proliferation negative regulation of neurogenesis negative regulation of neuron differentiation negative regulation of transforming growth factor beta3 production negative regulation of tumor necrosis factor production neuroblast proliferation neuromuscular synaptic transmission neuron projection development plasma membrane podocyte differentiation positive regulation of B cell apoptotic process positive regulation of CD4-positive, alpha-beta T cell proliferation positive regulation of MAP kinase activity positive regulation of T cell homeostatic proliferation positive regulation of T cell mediated immune response to tumor cell positive regulation of activated T cell proliferation positive regulation of alpha-beta T cell proliferation positive regulation of calcium-mediated signaling positive regulation of cell adhesion mediated by integrin positive regulation of cell-cell adhesion positive regulation of cell-cell adhesion mediated by integrin positive regulation of cytosolic calcium ion concentration positive regulation of inflammatory response to antigenic stimulus positive regulation of inflammatory response to wounding positive regulation of integrin activation positive regulation of nephron tubule epithelial cell differentiation positive regulation of neuron projection development positive regulation of peptidyl-tyrosine phosphorylation pre-B cell differentiation presynapse protein kinase binding protein tyrosine kinase activator activity regulation of B cell differentiation regulation of MAPK cascade regulation of cell-cell adhesion regulation of cell-cell adhesion mediated by integrin regulation of cytokine-mediated signaling pathway regulation of phosphorylation respiratory burst response to estrogen response to hypoxia response to molecule of bacterial origin synaptic vesicle endocytosis	GO:0001666 GO:0001775 GO:0001777 GO:0001783 GO:0001959 GO:0002237 GO:0002329 GO:0002523 GO:0002842 GO:0002863 GO:0002904 GO:0005886 GO:0007157 GO:0007159 GO:0007166 GO:0007204 GO:0007274 GO:0007405 GO:0007406 GO:0008637 GO:0009897 GO:0009986 GO:0010976 GO:0016020 GO:0016477 GO:0019722 GO:0019901 GO:0022407 GO:0022409 GO:0030246 GO:0030262 GO:0030296 GO:0030544 GO:0030889 GO:0031175 GO:0031295 GO:0031514 GO:0031528 GO:0032597 GO:0032600 GO:0032715 GO:0032720 GO:0032913 GO:0033622 GO:0033625 GO:0033630 GO:0033632 GO:0033634 GO:0034107 GO:0034109 GO:0034119 GO:0035739 GO:0042100 GO:0042103 GO:0042104 GO:0042325 GO:0042632 GO:0043231 GO:0043406 GO:0043408 GO:0043627 GO:0045087 GO:0045121 GO:0045577 GO:0045665 GO:0045730 GO:0046014 GO:0046641 GO:0048488 GO:0050731 GO:0050768 GO:0050850 GO:0051879 GO:0060170 GO:0071638 GO:0072112 GO:0072139 GO:0097190 GO:0098793 GO:0106015 GO:0106016 GO:2000563 GO:2000768
GL_000906	Polypeptide N-acetylgalactosaminyltransferase 17	Q7TT15	Mus musculus	10090	Golgi apparatus Golgi membrane carbohydrate binding metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation	GO:0000139 GO:0004653 GO:0005794 GO:0006493 GO:0030246 GO:0046872