GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID ▲	GO Labels	GO IDs
GL_001021	Pulmonary surfactant-associated protein A2	Q8IWL1	Homo sapiens	9606	carbohydrate binding clathrin-coated endocytic vesicle collagen trimer endoplasmic reticulum membrane extracellular region extracellular space lamellar body multivesicular body respiratory gaseous exchange by respiratory system	GO:0005576 GO:0005581 GO:0005615 GO:0005771 GO:0005789 GO:0007585 GO:0030246 GO:0042599 GO:0045334
GL_000807	Neurocan core protein	O14594	Homo sapiens	9606	Golgi lumen calcium ion binding carbohydrate binding cell adhesion central nervous system development extracellular region extracellular space glial cell differentiation hyaluronic acid binding lysosomal lumen perineuronal net positive regulation of neuroblast proliferation skeletal system development synapse	GO:0001501 GO:0002052 GO:0005509 GO:0005540 GO:0005576 GO:0005615 GO:0005796 GO:0007155 GO:0007417 GO:0010001 GO:0030246 GO:0043202 GO:0045202 GO:0072534
GL_001982	Asialoglycoprotein receptor 1	P07306	Homo sapiens	9606	asialoglycoprotein receptor activity cellular response to extracellular stimulus external side of plasma membrane extracellular region fucose binding identical protein binding mannose binding metal ion binding plasma membrane receptor-mediated endocytosis	GO:0004873 GO:0005537 GO:0005576 GO:0005886 GO:0006898 GO:0009897 GO:0031668 GO:0042802 GO:0042806 GO:0046872
GL_000679	Layilin	Q6UX15	Homo sapiens	9606	carbohydrate binding cell surface focal adhesion hyaluronic acid binding membrane ruffle	GO:0001726 GO:0005540 GO:0005925 GO:0009986 GO:0016020 GO:0030246
GL_002041	Lithostathine-1-alpha	P05451	Homo sapiens	9606	antimicrobial humoral immune response mediated by antimicrobial peptide extracellular exosome extracellular space growth factor activity molecular function inhibitor activity oligosaccharide binding peptidoglycan binding positive regulation of cell population proliferation response to peptide hormone signaling receptor activity	GO:0005615 GO:0008083 GO:0008284 GO:0038023 GO:0042834 GO:0043434 GO:0061844 GO:0070062 GO:0070492 GO:0140678
GL_001183	1,4-alpha-glucan-branching enzyme	Q04446	Homo sapiens	9606	1,4-alpha-glucan branching enzyme activity 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) carbohydrate binding cation binding cytoplasm cytosol extracellular exosome generation of precursor metabolites and energy glycogen biosynthetic process glycogen metabolic process hydrolase activity, hydrolyzing O-glycosyl compounds negative regulation of neuron apoptotic process	GO:0003844 GO:0004553 GO:0005737 GO:0005829 GO:0005977 GO:0005978 GO:0006091 GO:0030246 GO:0043169 GO:0043524 GO:0070062 GO:0102752
GL_000153	C-type lectin domain family 2 member D	Q9UHP7	Homo sapiens	9606	carbohydrate binding cell surface cell surface receptor signaling pathway endoplasmic reticulum external side of plasma membrane membrane plasma membrane transmembrane signaling receptor activity	GO:0004888 GO:0005783 GO:0005886 GO:0007166 GO:0009897 GO:0009986 GO:0016020 GO:0030246
GL_000185	C-type lectin domain family 4 member F	Q8N1N0	Homo sapiens	9606	carbohydrate binding endocytosis external side of plasma membrane	GO:0006897 GO:0009897 GO:0030246
GL_002069	Regenerating islet-derived protein 4	Q9BYZ8	Homo sapiens	9606	cytoplasm extracellular region heparin binding mannan binding response to bacterium signaling receptor activity	GO:0005576 GO:0005737 GO:0008201 GO:0009617 GO:0038023 GO:2001065
GL_000358	Early activation antigen CD69	Q07108	Homo sapiens	9606	carbohydrate binding cellular response to xenobiotic stimulus external side of plasma membrane identical protein binding plasma membrane protein-containing complex transmembrane signaling receptor activity	GO:0004888 GO:0005886 GO:0009897 GO:0030246 GO:0032991 GO:0042802 GO:0071466