GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID ▼	GO Labels	GO IDs
GL_000508	Galectin-7	O54974	Mus musculus	10090	apoptotic process carbohydrate binding cornified envelope cytoplasm extracellular region nucleus	GO:0001533 GO:0005576 GO:0005634 GO:0005737 GO:0006915 GO:0030246
GL_001180	Zymogen granule membrane protein 16	Q8K0C5	Mus musculus	10090	Golgi lumen carbohydrate binding collagen-containing extracellular matrix defense response to Gram-positive bacterium extracellular space mucus layer peptidoglycan binding protein transport suppression of symbiont entry into host zymogen granule membrane	GO:0005615 GO:0005796 GO:0015031 GO:0030246 GO:0042589 GO:0042834 GO:0050830 GO:0052373 GO:0062023 GO:0070701
GL_000177	C-type lectin domain family 4 member D	Q9Z2H6	Mus musculus	10090	Fc-gamma receptor signaling pathway T cell differentiation involved in immune response adaptive immune response antifungal innate immune response carbohydrate binding defense response to bacterium external side of plasma membrane immunoglobulin receptor binding innate immune response mannose binding metal ion binding pattern recognition receptor activity plasma membrane positive regulation of canonical NF-kappaB signal transduction positive regulation of myeloid dendritic cell activation	GO:0002250 GO:0002292 GO:0005537 GO:0005886 GO:0009897 GO:0030246 GO:0030887 GO:0034987 GO:0038094 GO:0038187 GO:0042742 GO:0043123 GO:0045087 GO:0046872 GO:0061760
GL_000812	Neuronal pentraxin-2	O70340	Mus musculus	10090	associative learning carbohydrate binding extrinsic component of postsynaptic specialization membrane glutamatergic synapse metal ion binding neurotransmitter receptor localization to postsynaptic specialization membrane synaptic cleft	GO:0008306 GO:0030246 GO:0043083 GO:0046872 GO:0098892 GO:0098978 GO:0099645
GL_000078	B-cell receptor CD22	P35329	Mus musculus	10090	B cell activation CD4 receptor binding carbohydrate binding cell adhesion cell surface cell surface receptor signaling pathway coreceptor activity early endosome external side of plasma membrane negative regulation of B cell receptor signaling pathway negative regulation of calcium-mediated signaling negative regulation of immunoglobulin production neuronal cell body membrane plasma membrane protein phosphatase binding recycling endosome regulation of B cell proliferation regulation of endocytosis regulation of immune response sialic acid binding	GO:0002638 GO:0005769 GO:0005886 GO:0007155 GO:0007166 GO:0009897 GO:0009986 GO:0015026 GO:0019903 GO:0030100 GO:0030246 GO:0030888 GO:0032809 GO:0033691 GO:0042113 GO:0042609 GO:0050776 GO:0050849 GO:0050859 GO:0055037
GL_001195	Adhesion G protein-coupled receptor L2	Q8JZZ7	Mus musculus	10090	G protein-coupled receptor activity PDZ domain binding adenylate cyclase-activating G protein-coupled receptor signaling pathway carbohydrate binding cell surface receptor signaling pathway glutamatergic synapse positive regulation of synapse assembly postsynaptic membrane response to bacterium synapse organization	GO:0004930 GO:0007166 GO:0007189 GO:0009617 GO:0030165 GO:0030246 GO:0045211 GO:0050808 GO:0051965 GO:0098978
GL_002048	P-selectin	Q01102	Mus musculus	10090	calcium ion binding calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules calcium-dependent protein binding calcium-mediated signaling using intracellular calcium source cell-cell adhesion cellular response to interleukin-6 external side of plasma membrane extracellular space fucose binding heparin binding heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules inflammatory response leukocyte cell-cell adhesion leukocyte migration leukocyte tethering or rolling lipopolysaccharide binding membrane oligosaccharide binding plasma membrane platelet alpha granule membrane positive regulation of cell adhesion positive regulation of leukocyte migration positive regulation of leukocyte tethering or rolling positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of platelet activation regulation of cellular extravasation regulation of integrin activation response to cytokine sialic acid binding	GO:0001530 GO:0002687 GO:0002691 GO:0005509 GO:0005615 GO:0005886 GO:0006954 GO:0007157 GO:0007159 GO:0008201 GO:0009897 GO:0010572 GO:0016020 GO:0016339 GO:0031092 GO:0033623 GO:0033691 GO:0034097 GO:0035584 GO:0042806 GO:0045785 GO:0048306 GO:0050900 GO:0050901 GO:0051897 GO:0070492 GO:0071354 GO:0098609 GO:1903238
GL_001670	Keratin, type II cytoskeletal 1	P04104	Mus musculus	10090	carbohydrate binding collagen-containing extracellular matrix complement activation, lectin pathway cornified envelope cytoplasm establishment of skin barrier intermediate filament organization keratin filament keratinization membrane negative regulation of inflammatory response protein heterodimerization activity protein heterotetramerization structural constituent of skin epidermis	GO:0001533 GO:0001867 GO:0005737 GO:0016020 GO:0030246 GO:0030280 GO:0031424 GO:0045095 GO:0045109 GO:0046982 GO:0050728 GO:0051290 GO:0061436 GO:0062023
GL_000889	Polypeptide N-acetylgalactosaminyltransferase 10	Q6P9S7	Mus musculus	10090	Golgi apparatus Golgi membrane O-glycan processing carbohydrate binding metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation	GO:0000139 GO:0004653 GO:0005794 GO:0006493 GO:0016266 GO:0030246 GO:0046872
GL_000767	Lymphocyte antigen 75	Q60767	Mus musculus	10090	carbohydrate binding endocytosis external side of plasma membrane signaling receptor activity	GO:0006897 GO:0009897 GO:0030246 GO:0038023