GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database Last Updated
MCAW-DB July 10, 2019
UniLectin June 14, 2023
UniProt February 16, 2024
Lectin Frontier DataBase (LfDB) February 16, 2024
CarboGrove June 14, 2023
GlyCosmos Lectin Lectin Name UniProt ID ▲ Monosaccharide Specificities Species Taxonomy ID GO Labels GO IDs
Complement component C1q receptor
9606
  • calcium ion binding
  • carbohydrate binding
  • cell surface
  • cell-cell adhesion
  • complement component C1q complex binding
  • ficolin-1-rich granule membrane
  • macrophage activation
  • phagocytosis
  • plasma membrane
  • secretory granule membrane
  • signaling receptor activity
  • specific granule membrane
  • tertiary granule membrane
  • GO:0001849
  • GO:0005509
  • GO:0005886
  • GO:0006909
  • GO:0009986
  • GO:0030246
  • GO:0030667
  • GO:0035579
  • GO:0038023
  • GO:0042116
  • GO:0070821
  • GO:0098609
  • GO:0101003
F-box only protein 6
9606
  • DNA damage checkpoint signaling
  • DNA repair
  • SCF ubiquitin ligase complex
  • SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
  • carbohydrate binding
  • cytoplasm
  • cytosol
  • endoplasmic reticulum quality control compartment
  • glycoprotein catabolic process
  • protein ubiquitination
  • proteolysis
  • response to unfolded protein
  • ubiquitin protein ligase activity
  • ubiquitin-dependent ERAD pathway
  • GO:0000077
  • GO:0005737
  • GO:0005829
  • GO:0006281
  • GO:0006508
  • GO:0006516
  • GO:0006986
  • GO:0016567
  • GO:0019005
  • GO:0030246
  • GO:0030433
  • GO:0031146
  • GO:0044322
  • GO:0061630
Alpha-mannosidase 2C1
9606
  • alpha-mannosidase activity
  • carbohydrate binding
  • cytosol
  • mannose metabolic process
  • metal ion binding
  • nucleoplasm
  • oligosaccharide catabolic process
  • GO:0004559
  • GO:0005654
  • GO:0005829
  • GO:0006013
  • GO:0009313
  • GO:0030246
  • GO:0046872
C-type lectin domain family 5 member A
9606
  • carbohydrate binding
  • cell surface
  • cellular defense response
  • cytosol
  • innate immune response
  • myeloid cell differentiation
  • negative regulation of apoptotic process
  • negative regulation of myeloid cell apoptotic process
  • osteoblast development
  • plasma membrane
  • positive regulation of cytokine production
  • signal transduction
  • specific granule membrane
  • tertiary granule membrane
  • virus receptor activity
  • GO:0001618
  • GO:0001819
  • GO:0002076
  • GO:0005829
  • GO:0005886
  • GO:0006968
  • GO:0007165
  • GO:0009986
  • GO:0030099
  • GO:0030246
  • GO:0033033
  • GO:0035579
  • GO:0043066
  • GO:0045087
  • GO:0070821
Probable polypeptide N-acetylgalactosaminyltransferase 8
9606
  • Golgi apparatus
  • Golgi membrane
  • O-glycan processing
  • carbohydrate binding
  • metal ion binding
  • polypeptide N-acetylgalactosaminyltransferase activity
  • protein O-linked glycosylation
  • GO:0000139
  • GO:0004653
  • GO:0005794
  • GO:0006493
  • GO:0016266
  • GO:0030246
  • GO:0046872
Sialic acid-binding Ig-like lectin 8
9606
  • carbohydrate binding
  • cell adhesion
  • membrane
  • plasma membrane
  • sialic acid binding
  • signal transduction
  • transmembrane signaling receptor activity
  • GO:0004888
  • GO:0005886
  • GO:0007155
  • GO:0007165
  • GO:0016020
  • GO:0030246
  • GO:0033691
Killer cell lectin-like receptor subfamily F member 1
9606
  • MHC class I receptor activity
  • carbohydrate binding
  • cell surface receptor signaling pathway
  • membrane
  • plasma membrane
  • transmembrane signaling receptor activity
  • GO:0004888
  • GO:0005886
  • GO:0007166
  • GO:0016020
  • GO:0030246
  • GO:0032393
C-type lectin domain family 1 member B
9606
  • carbohydrate binding
  • cell surface
  • cell surface receptor signaling pathway
  • defense response
  • plasma membrane
  • platelet formation
  • signal transduction
  • transmembrane signaling receptor activity
  • GO:0004888
  • GO:0005886
  • GO:0006952
  • GO:0007165
  • GO:0007166
  • GO:0009986
  • GO:0030220
  • GO:0030246
Galectin-2
5346
  • carbohydrate binding
  • endomembrane system
  • extracellular region
  • membrane
  • GO:0005576
  • GO:0012505
  • GO:0016020
  • GO:0030246
Alpha-xylosidase
273057
  • alpha-D-xyloside xylohydrolase
  • carbohydrate binding
  • carbohydrate metabolic process
  • GO:0005975
  • GO:0030246
  • GO:0061634
Displaying entries 2261 - 2270 of 2433 in total

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01