GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database Last Updated
MCAW-DB July 10, 2019
UniLectin June 14, 2023
UniProt February 16, 2024
Lectin Frontier DataBase (LfDB) February 16, 2024
CarboGrove June 14, 2023
GlyCosmos Lectin Lectin Name UniProt ID Monosaccharide Specificities Species Taxonomy ID GO Labels GO IDs
Killer cell lectin-like receptor subfamily B member 1A
10090
  • carbohydrate binding
  • cell surface
  • plasma membrane
  • regulation of natural killer cell mediated cytotoxicity
  • signaling receptor activity
  • GO:0005886
  • GO:0009986
  • GO:0030246
  • GO:0038023
  • GO:0042269
Killer cell lectin-like receptor 3
10090
  • carbohydrate binding
  • cell adhesion
  • plasma membrane
  • GO:0005886
  • GO:0007155
  • GO:0030246
Beta-galactosidase
1488
  • beta-galactosidase activity
  • beta-galactosidase complex
  • carbohydrate binding
  • carbohydrate metabolic process
  • organic substance catabolic process
  • GO:0004565
  • GO:0005975
  • GO:0009341
  • GO:0030246
  • GO:1901575
C-type lectin domain-containing protein 88
6239
  • carbohydrate binding
  • external side of plasma membrane
  • GO:0009897
  • GO:0030246
Endoglucanase 19
3702
  • carbohydrate binding
  • cell wall organization
  • cellulase activity
  • cellulose catabolic process
  • extracellular region
  • GO:0005576
  • GO:0008810
  • GO:0030245
  • GO:0030246
  • GO:0071555
Chitinase-3-like protein 1
9940
  • activation of NF-kappaB-inducing kinase activity
  • apoptotic process
  • carbohydrate binding
  • carbohydrate metabolic process
  • cellular response to tumor necrosis factor
  • chitin binding
  • cytoplasm
  • endoplasmic reticulum
  • extracellular space
  • inflammatory response
  • lung development
  • perinuclear region of cytoplasm
  • positive regulation of ERK1 and ERK2 cascade
  • positive regulation of angiogenesis
  • positive regulation of interleukin-8 production
  • positive regulation of peptidyl-threonine phosphorylation
  • positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
  • response to interleukin-1
  • response to interleukin-6
  • response to mechanical stimulus
  • response to tumor necrosis factor
  • GO:0005615
  • GO:0005737
  • GO:0005783
  • GO:0005975
  • GO:0006915
  • GO:0006954
  • GO:0007250
  • GO:0008061
  • GO:0009612
  • GO:0010800
  • GO:0030246
  • GO:0030324
  • GO:0032757
  • GO:0034612
  • GO:0045766
  • GO:0048471
  • GO:0051897
  • GO:0070374
  • GO:0070555
  • GO:0070741
  • GO:0071356
E-selectin
9796
  • calcium ion binding
  • external side of plasma membrane
  • extracellular space
  • heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
  • leukocyte tethering or rolling
  • oligosaccharide binding
  • positive regulation of leukocyte tethering or rolling
  • response to cytokine
  • sialic acid binding
  • GO:0005509
  • GO:0005615
  • GO:0007157
  • GO:0009897
  • GO:0033691
  • GO:0034097
  • GO:0050901
  • GO:0070492
  • GO:1903238
Contactin-1
10090
  • Notch signaling pathway
  • axon
  • axon guidance
  • brain development
  • carbohydrate binding
  • cell-cell adhesion
  • cell-cell adhesion mediator activity
  • central nervous system myelin formation
  • cerebellum development
  • gene expression
  • locomotory behavior
  • myelin sheath
  • myelination
  • neuron projection development
  • plasma membrane
  • positive regulation of gene expression
  • positive regulation of neuron projection development
  • positive regulation of peptidyl-tyrosine phosphorylation
  • positive regulation of sodium ion transport
  • postsynaptic membrane
  • presynaptic membrane
  • side of membrane
  • GO:0005886
  • GO:0007219
  • GO:0007411
  • GO:0007420
  • GO:0007626
  • GO:0010467
  • GO:0010628
  • GO:0010765
  • GO:0010976
  • GO:0021549
  • GO:0030246
  • GO:0030424
  • GO:0031175
  • GO:0032289
  • GO:0042552
  • GO:0042734
  • GO:0043209
  • GO:0045211
  • GO:0050731
  • GO:0098552
  • GO:0098609
  • GO:0098632
Type-2 ice-structuring protein
1633465
  • carbohydrate binding
  • extracellular region
  • GO:0005576
  • GO:0030246
ER degradation-enhancing alpha-mannosidase-like protein 1
284812
  • calcium ion binding
  • carbohydrate binding
  • carbohydrate metabolic process
  • cytosol
  • endoplasmic reticulum
  • endoplasmic reticulum lumen
  • membrane
  • response to unfolded protein
  • ubiquitin-dependent glycoprotein ERAD pathway
  • GO:0005509
  • GO:0005783
  • GO:0005788
  • GO:0005829
  • GO:0005975
  • GO:0006986
  • GO:0016020
  • GO:0030246
  • GO:0097466
Displaying entries 2271 - 2280 of 2433 in total

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01