GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID ▼	GO Labels	GO IDs
GL_002043	Lithostathine-2	Q08731	Mus musculus	10090	antimicrobial humoral immune response mediated by antimicrobial peptide collagen-containing extracellular matrix extracellular space molecular function inhibitor activity myelination oligosaccharide binding peptidoglycan binding positive regulation of cell population proliferation response to peptide hormone signaling receptor activity suckling behavior	GO:0001967 GO:0005615 GO:0008284 GO:0038023 GO:0042552 GO:0042834 GO:0043434 GO:0061844 GO:0062023 GO:0070492 GO:0140678
GL_000362	Endosialin	Q91V98	Mus musculus	10090	anatomical structure regression calcium ion binding carbohydrate binding cell migration cytoplasm endothelial cell apoptotic process external side of plasma membrane extracellular matrix binding extracellular matrix protein binding fibroblast migration fibroblast proliferation lymph node development plasma membrane positive regulation of endothelial cell apoptotic process positive regulation of fibroblast proliferation	GO:0005509 GO:0005737 GO:0005886 GO:0009897 GO:0010761 GO:0016477 GO:0030246 GO:0048144 GO:0048146 GO:0048535 GO:0050840 GO:0060033 GO:0072577 GO:1990430 GO:2000353
GL_001385	CDP-diacylglycerol--inositol 3-phosphatidyltransferase	Q8VDP6	Mus musculus	10090	CDP-diacylglycerol metabolic process CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity Golgi apparatus alcohol binding carbohydrate binding diacylglycerol binding endoplasmic reticulum membrane manganese ion binding membrane phosphatidylinositol biosynthetic process plasma membrane	GO:0003881 GO:0005789 GO:0005794 GO:0005886 GO:0006661 GO:0016020 GO:0019992 GO:0030145 GO:0030246 GO:0043178 GO:0046341
GL_002261	Igh protein	Q99LC4	Mus musculus	10090	metal ion binding	GO:0046872
GL_001184	1,4-alpha-glucan-branching enzyme	Q9D6Y9	Mus musculus	10090	1,4-alpha-glucan branching enzyme activity 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) carbohydrate binding cation binding cytoplasm cytosol glycogen biosynthetic process hydrolase activity, hydrolyzing O-glycosyl compounds negative regulation of neuron apoptotic process	GO:0003844 GO:0004553 GO:0005737 GO:0005829 GO:0005978 GO:0030246 GO:0043169 GO:0043524 GO:0102752
GL_000385	Ficolin-1	O70165	Mus musculus	10090	G protein-coupled receptor signaling pathway antigen binding carbohydrate binding carbohydrate derivative binding cell surface pattern recognition receptor signaling pathway collagen trimer collagen-containing extracellular matrix complement activation, lectin pathway extracellular space metal ion binding pattern recognition receptor activity plasma membrane positive regulation of interleukin-8 production signaling receptor binding	GO:0001867 GO:0002752 GO:0003823 GO:0005102 GO:0005581 GO:0005615 GO:0005886 GO:0007186 GO:0030246 GO:0032757 GO:0038187 GO:0046872 GO:0062023 GO:0097367
GL_001458	Epididymis-specific alpha-mannosidase	O54782	Mus musculus	10090	alpha-mannosidase activity carbohydrate binding extracellular region lysosomal lumen lysosome mannan endo-1,6-alpha-mannosidase activity mannose metabolic process metal ion binding oligosaccharide catabolic process	GO:0004559 GO:0005576 GO:0005764 GO:0006013 GO:0008496 GO:0009313 GO:0030246 GO:0043202 GO:0046872
GL_000167	C-type lectin domain family 2 member L	P0C7M9	Mus musculus	10090	carbohydrate binding membrane	GO:0016020 GO:0030246
GL_001721	Nectin-1	Q9JKF6	Mus musculus	10090	adherens junction apical junction complex axon axon guidance camera-type eye morphogenesis carbohydrate binding cell adhesion molecule binding cell-cell adhesion cell-cell contact zone dendrite desmosome organization enamel mineralization growth cone membrane heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules hippocampal mossy fiber to CA3 synapse homophilic cell adhesion via plasma membrane adhesion molecules identical protein binding iron ion transport lens morphogenesis in camera-type eye membrane presynaptic active zone membrane protein homodimerization activity protein localization to cell junction protein-containing complex binding regulation of synapse assembly regulation of synapse organization retina development in camera-type eye signaling receptor activity viral entry into host cell virion binding	GO:0002089 GO:0002934 GO:0005912 GO:0006826 GO:0007156 GO:0007157 GO:0007411 GO:0016020 GO:0030246 GO:0030424 GO:0030425 GO:0032584 GO:0038023 GO:0042802 GO:0042803 GO:0043296 GO:0044291 GO:0044877 GO:0046718 GO:0046790 GO:0048593 GO:0048787 GO:0050807 GO:0050839 GO:0051963 GO:0060041 GO:0070166 GO:0098609 GO:0098686 GO:1902414
GL_001647	Hematopoietic progenitor cell antigen CD34	Q64314	Mus musculus	10090	RNA polymerase II-specific DNA-binding transcription factor binding apical plasma membrane basal plasma membrane carbohydrate binding cell periphery cell surface cell-cell adhesion cell-matrix adhesion cytoplasm endothelial cell proliferation external side of plasma membrane extracellular exosome assembly extracellular region glomerular endothelium development glomerular endothelium fenestra glomerular filtration hematopoietic stem cell proliferation hemopoiesis intercellular bridge leukocyte migration lysosome membrane mesangial cell-matrix adhesion metanephric glomerular mesangial cell differentiation negative regulation of gene expression negative regulation of interleukin-2 production paracrine signaling perinuclear region of cytoplasm plasma membrane positive regulation of angiogenesis positive regulation of granulocyte colony-stimulating factor production positive regulation of odontogenesis positive regulation of vasculogenesis signal transduction sulfate binding tissue homeostasis transdifferentiation vascular wound healing	GO:0001894 GO:0001935 GO:0003094 GO:0005576 GO:0005737 GO:0005764 GO:0005886 GO:0007160 GO:0007165 GO:0009897 GO:0009925 GO:0009986 GO:0010629 GO:0016020 GO:0016324 GO:0030097 GO:0030246 GO:0032703 GO:0035759 GO:0036053 GO:0038001 GO:0042482 GO:0043199 GO:0045171 GO:0045766 GO:0048471 GO:0050900 GO:0060290 GO:0061042 GO:0061629 GO:0071425 GO:0071657 GO:0071944 GO:0071971 GO:0072011 GO:0072254 GO:0098609 GO:2001214