GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID	GO Labels	GO IDs
GL_002366	Fimbrial protein MyfA	P33406	Yersinia enterocolitica	630	pilus	GO:0009289
GL_000291	Calreticulin (Fragment)	P31832	Pelophylax lessonae	45623	carbohydrate binding endoplasmic reticulum lumen metal ion binding	GO:0005788 GO:0030246 GO:0046872
GL_000643	L-type lectin-domain containing receptor kinase I.9	Q9LSR8	Arabidopsis thaliana	3702	ATP binding carbohydrate binding cellular response to ATP defense response defense response to oomycetes extracellular ATP signaling focal adhesion assembly phosphorylation plasma membrane protein serine kinase activity protein serine/threonine kinase activity regulation of jasmonic acid mediated signaling pathway response to wounding	GO:0002229 GO:0004674 GO:0005524 GO:0005886 GO:0006952 GO:0009611 GO:0016310 GO:0030246 GO:0048041 GO:0071318 GO:0106167 GO:0106310 GO:2000022
GL_001743	Pleiotrophin	P63090	Rattus norvegicus	10116	Schaffer collateral - CA1 synapse basement membrane bone mineralization carbohydrate binding cell surface cellular response to UV cellular response to hypoxia cellular response to organic cyclic compound cellular response to platelet-derived growth factor stimulus cellular response to vitamin D cerebellum development chondroitin sulfate binding chondroitin sulfate proteoglycan binding decidualization dendrite arborization dendrite regeneration endothelial cell differentiation estrous cycle extracellular region extracellular space glycosaminoglycan binding growth factor activity heart development heparan sulfate binding heparin binding hindbrain development integrin binding integrin-mediated signaling pathway learning leukocyte chemotaxis involved in inflammatory response liver development long-term synaptic potentiation lung development memory modulation of chemical synaptic transmission molecular function activator activity negative regulation of angiogenesis negative regulation of cell migration negative regulation of epithelial cell proliferation negative regulation of glial cell proliferation negative regulation of long-term synaptic potentiation negative regulation of membrane potential negative regulation of mesenchymal cell proliferation negative regulation of neuroblast proliferation negative regulation of neuromuscular junction development neuromuscular junction oogenesis ossification ossification involved in bone remodeling perinuclear region of cytoplasm plasma membrane positive regulation of apoptotic process positive regulation of axon regeneration positive regulation of bone mineralization positive regulation of cell differentiation positive regulation of cell division positive regulation of cell population proliferation positive regulation of cell-substrate adhesion positive regulation of dendrite development positive regulation of hepatocyte proliferation positive regulation of leukocyte chemotaxis positive regulation of neuron projection development positive regulation of oligodendrocyte differentiation positive regulation of ossification positive regulation of skeletal muscle acetylcholine-gated channel clustering positive regulation of stem cell differentiation postsynapse presynapse protein kinase binding protein phosphatase inhibitor activity protein-containing complex proteoglycan binding receptor clustering regulation of cell shape regulation of endothelial cell migration regulation of hemopoiesis regulation of myelination regulation of stem cell population maintenance regulation of synaptic plasticity response to activity response to auditory stimulus response to ciliary neurotrophic factor response to estradiol response to kainic acid response to nerve growth factor response to progesterone response to xenobiotic stimulus retina development in camera-type eye retinal rod cell differentiation rod bipolar cell differentiation spinal cord development syndecan binding thalamus development tissue regeneration vascular endothelial growth factor binding	GO:0001503 GO:0001889 GO:0002232 GO:0002690 GO:0004864 GO:0005178 GO:0005539 GO:0005576 GO:0005604 GO:0005615 GO:0005886 GO:0007229 GO:0007406 GO:0007507 GO:0007612 GO:0007613 GO:0008083 GO:0008201 GO:0008284 GO:0008360 GO:0009410 GO:0009986 GO:0010594 GO:0010811 GO:0010976 GO:0010996 GO:0014823 GO:0016525 GO:0019901 GO:0021510 GO:0021549 GO:0021794 GO:0030246 GO:0030282 GO:0030324 GO:0030336 GO:0030501 GO:0030902 GO:0031104 GO:0031594 GO:0031641 GO:0032355 GO:0032570 GO:0032991 GO:0034644 GO:0035373 GO:0035374 GO:0036120 GO:0038085 GO:0042246 GO:0043065 GO:0043113 GO:0043394 GO:0043932 GO:0044849 GO:0045446 GO:0045545 GO:0045597 GO:0045778 GO:0045837 GO:0046697 GO:0048167 GO:0048471 GO:0048477 GO:0048680 GO:0048714 GO:0050680 GO:0050804 GO:0051781 GO:0060041 GO:0060221 GO:0060253 GO:0060291 GO:0071305 GO:0071407 GO:0071456 GO:0072201 GO:0098685 GO:0098793 GO:0098794 GO:0140059 GO:0140677 GO:1900006 GO:1900272 GO:1903706 GO:1904373 GO:1904389 GO:1904391 GO:1904395 GO:1904397 GO:1904399 GO:1990089 GO:2000036 GO:2000347 GO:2000738
GL_001456	Endomucin	Q9R0H2	Mus musculus	10090	angiogenesis carbohydrate binding cell-cell adhesion hematopoietic stem cell homeostasis membrane plasma membrane regulation of cell adhesion	GO:0001525 GO:0005886 GO:0016020 GO:0030155 GO:0030246 GO:0061484 GO:0098609
GL_001452	Endoglucanase A	P06566	Evansella cellulosilytica DSM 2522	649639	carbohydrate binding cellulase activity cellulose catabolic process extracellular region	GO:0005576 GO:0008810 GO:0030245 GO:0030246
GL_000529	Glucan endo-1,3-beta-glucosidase	Q59146	Arthrobacter sp. YCWD3	79671	carbohydrate binding cell wall organization glucan endo-1,3-beta-D-glucosidase activity metabolic process periplasmic space	GO:0008152 GO:0030246 GO:0042597 GO:0042973 GO:0071555
GL_002336	Botulinum neurotoxin type A	P0DPI1	Clostridium botulinum A str. Hall	441771	extracellular region host cell cytoplasmic vesicle host cell cytosol host cell plasma membrane host cell presynaptic membrane membrane metalloendopeptidase activity protein transmembrane transporter activity proteolysis toxin activity zinc ion binding	GO:0004222 GO:0005576 GO:0006508 GO:0008270 GO:0008320 GO:0016020 GO:0020002 GO:0044161 GO:0044164 GO:0044231 GO:0090729
GL_000768	Lymphocyte antigen 75	O60449	Homo sapiens	9606	carbohydrate binding endocytosis external side of plasma membrane extracellular exosome immune response inflammatory response plasma membrane signaling receptor activity	GO:0005886 GO:0006897 GO:0006954 GO:0006955 GO:0009897 GO:0030246 GO:0038023 GO:0070062
GL_000963	Protein EMP46	Q12396	Saccharomyces cerevisiae S288C	559292	COPII-coated ER to Golgi transport vesicle Golgi membrane carbohydrate binding endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum to Golgi vesicle-mediated transport endoplasmic reticulum-Golgi intermediate compartment mannose binding metal ion binding protein transport	GO:0000139 GO:0005537 GO:0005783 GO:0005789 GO:0005793 GO:0006888 GO:0015031 GO:0030134 GO:0030246 GO:0046872