GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID ▼	GO Labels	GO IDs
GL_002070	Regenerating islet-derived protein 4	Q9D8G5	Mus musculus	10090	cytoplasm extracellular space heparin binding mannan binding response to bacterium signaling receptor activity	GO:0005615 GO:0005737 GO:0008201 GO:0009617 GO:0038023 GO:2001065
GL_002062	Regenerating islet-derived protein 3-alpha	O09037	Mus musculus	10090	acute-phase response antimicrobial humoral immune response mediated by antimicrobial peptide extracellular space hormone activity identical protein binding metal ion binding negative regulation of inflammatory response to wounding negative regulation of keratinocyte differentiation oligosaccharide binding peptidoglycan binding positive regulation of cell population proliferation positive regulation of keratinocyte proliferation positive regulation of wound healing response to peptide hormone response to wounding signaling receptor activity	GO:0005179 GO:0005615 GO:0006953 GO:0008284 GO:0009611 GO:0010838 GO:0038023 GO:0042802 GO:0042834 GO:0043434 GO:0045617 GO:0046872 GO:0061844 GO:0070492 GO:0090303 GO:0106015
GL_000795	N-acetylgalactosaminyltransferase 7	Q80VA0	Mus musculus	10090	Golgi apparatus Golgi membrane carbohydrate binding metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation	GO:0000139 GO:0004653 GO:0005794 GO:0006493 GO:0030246 GO:0046872
GL_000913	Polypeptide N-acetylgalactosaminyltransferase 3	P70419	Mus musculus	10090	Golgi apparatus Golgi cisterna membrane calcium ion binding carbohydrate binding manganese ion binding perinuclear region of cytoplasm polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation protein O-linked glycosylation via serine protein O-linked glycosylation via threonine spermatogenesis	GO:0004653 GO:0005509 GO:0005794 GO:0006493 GO:0007283 GO:0018242 GO:0018243 GO:0030145 GO:0030246 GO:0032580 GO:0048471
GL_001680	Laforin	Q9WUA5	Mus musculus	10090	L-glutamate transmembrane transport Wnt signaling pathway autophagosome assembly autophagy calcium ion transport carbohydrate binding carbohydrate phosphatase activity carbohydrate phosphorylation cytoplasm cytoplasmic side of endoplasmic reticulum membrane cytoplasmic side of rough endoplasmic reticulum membrane cytosol dendrite dephosphorylation glial cell proliferation glycogen (starch) synthase activity glycogen binding glycogen biosynthetic process glycogen metabolic process habituation identical protein binding macromolecule metabolic process mitochondrion organization myosin phosphatase activity negative regulation of TOR signaling negative regulation of cell cycle negative regulation of dephosphorylation negative regulation of gene expression negative regulation of peptidyl-serine phosphorylation nervous system development nucleoplasm nucleus perikaryon phosphatase activity phosphoprotein phosphatase activity plasma membrane polysaccharide binding polysome positive regulation of macroautophagy proteasome-mediated ubiquitin-dependent protein catabolic process protein dimerization activity protein homodimerization activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity protein tyrosine/serine/threonine phosphatase activity regulation of cell growth regulation of gene expression regulation of phosphorylation regulation of proteasomal protein catabolic process regulation of protein import into nucleus regulation of protein localization to plasma membrane regulation of protein phosphorylation regulation of protein ubiquitination starch binding	GO:0000045 GO:0001558 GO:0001932 GO:0004373 GO:0004721 GO:0004722 GO:0004725 GO:0005634 GO:0005654 GO:0005737 GO:0005829 GO:0005844 GO:0005886 GO:0005977 GO:0005978 GO:0006816 GO:0006914 GO:0007005 GO:0007399 GO:0008138 GO:0010468 GO:0010629 GO:0014009 GO:0015813 GO:0016055 GO:0016239 GO:0016311 GO:0016791 GO:0017018 GO:0019203 GO:0030246 GO:0030247 GO:0030425 GO:0031396 GO:0032007 GO:0033137 GO:0035305 GO:0042306 GO:0042325 GO:0042802 GO:0042803 GO:0043161 GO:0043170 GO:0043204 GO:0045786 GO:0046835 GO:0046959 GO:0046983 GO:0061136 GO:0098554 GO:0098556 GO:1903076 GO:2001069 GO:2001070
GL_000909	Polypeptide N-acetylgalactosaminyltransferase 18	Q8K1B9	Mus musculus	10090	Golgi apparatus Golgi membrane carbohydrate binding metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation	GO:0000139 GO:0004653 GO:0005794 GO:0006493 GO:0030246 GO:0046872
GL_001633	Glucose-6-phosphate 1-dehydrogenase X	Q00612	Mus musculus	10090	NADP binding NADP biosynthetic process NADP metabolic process NADPH regeneration angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure carbohydrate binding cellular response to oxidative stress centriolar satellite cholesterol biosynthetic process cytoplasm cytoplasmic side of plasma membrane cytosol erythrocyte development erythrocyte maturation glucose 6-phosphate metabolic process glucose binding glucose metabolic process glucose-6-phosphate dehydrogenase activity glutathione metabolic process identical protein binding intracellular membrane-bounded organelle negative regulation of cell growth involved in cardiac muscle cell development negative regulation of protein glutathionylation negative regulation of reactive oxygen species metabolic process pentose biosynthetic process pentose-phosphate shunt pentose-phosphate shunt, oxidative branch positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel protein homodimerization activity regulation of multicellular organism growth regulation of neuron apoptotic process response to ethanol response to oxidative stress ribose phosphate biosynthetic process	GO:0001998 GO:0002033 GO:0004345 GO:0005536 GO:0005737 GO:0005829 GO:0006006 GO:0006098 GO:0006695 GO:0006739 GO:0006740 GO:0006741 GO:0006749 GO:0006979 GO:0009051 GO:0009898 GO:0010734 GO:0019322 GO:0030246 GO:0034451 GO:0034599 GO:0040014 GO:0042802 GO:0042803 GO:0043231 GO:0043249 GO:0043523 GO:0045471 GO:0046390 GO:0048821 GO:0050661 GO:0051156 GO:0061052 GO:1904879 GO:2000378
GL_000471	Galectin-1	P16045	Mus musculus	10090	T cell costimulation apoptotic process carbohydrate binding cell surface cell-cell adhesion collagen-containing extracellular matrix cytosol extracellular region extracellular space galactose binding galectin complex heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules identical protein binding lactose binding laminin binding myoblast differentiation negative regulation of cell-substrate adhesion negative regulation of neuron projection development plasma cell differentiation positive regulation of apoptotic process positive regulation of erythrocyte aggregation positive regulation of inflammatory response positive regulation of viral entry into host cell	GO:0002317 GO:0005534 GO:0005576 GO:0005615 GO:0005829 GO:0006915 GO:0007157 GO:0009986 GO:0010812 GO:0010977 GO:0030246 GO:0030395 GO:0031295 GO:0034120 GO:0042802 GO:0043065 GO:0043236 GO:0045445 GO:0046598 GO:0050729 GO:0062023 GO:0098609 GO:1990724
GL_000628	Killer cell lectin-like receptor subfamily G member 1	O88713	Mus musculus	10090	carbohydrate binding cell surface receptor signaling pathway innate immune response intracellular membrane-bounded organelle plasma membrane	GO:0005886 GO:0007166 GO:0030246 GO:0043231 GO:0045087
GL_002023	Intelectin-1b	Q80ZA0	Mus musculus	10090	calcium ion binding defense response to nematode extracellular space identical protein binding oligosaccharide binding plasma membrane positive regulation of glucose import positive regulation of protein phosphorylation protein homotrimerization response to nematode side of membrane	GO:0001934 GO:0002215 GO:0005509 GO:0005615 GO:0005886 GO:0009624 GO:0042802 GO:0046326 GO:0070207 GO:0070492 GO:0098552