GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Monosaccharide Specificities	Species	Taxonomy ID	GO Labels ▼	GO IDs
GL_002284	Genome polyprotein	V9VEF3		Coxsackievirus A24	12089	ATP binding DNA-templated transcription RNA binding RNA helicase activity RNA-dependent RNA polymerase activity T=pseudo3 icosahedral viral capsid cysteine-type endopeptidase activity cytoplasmic vesicle membrane endocytosis involved in viral entry into host cell host cell cytoplasmic vesicle membrane host cell nucleus induction by virus of host autophagy metal ion binding monoatomic ion channel activity pore-mediated entry of viral genome into host cell protein complex oligomerization proteolysis ribonucleoside triphosphate phosphatase activity structural molecule activity suppression by virus of host gene expression suppression by virus of host innate immune response suppression by virus of host mRNA export from nucleus viral RNA genome replication virion attachment to host cell virus-mediated pore formation in host cell membrane	GO:0003723 GO:0003724 GO:0003968 GO:0004197 GO:0005198 GO:0005216 GO:0005524 GO:0006351 GO:0006508 GO:0017111 GO:0019062 GO:0030659 GO:0039503 GO:0039520 GO:0039522 GO:0039618 GO:0039657 GO:0039694 GO:0039707 GO:0042025 GO:0044162 GO:0044694 GO:0046872 GO:0051259 GO:0075509
GL_002310	Genome polyprotein	P03305		Foot-and-mouth disease virus (strain O1)	73482	ATP binding DNA-templated transcription RNA binding RNA helicase activity RNA-dependent RNA polymerase activity T=pseudo3 icosahedral viral capsid clathrin-dependent endocytosis of virus by host cell cysteine-type endopeptidase activity host cell cytoplasmic vesicle membrane host cell endoplasmic reticulum membrane host cell nucleus induction by virus of host autophagy membrane modulation by virus of host chromatin organization molecular adaptor activity monoatomic ion channel activity protein complex oligomerization proteolysis regulation of translation ribonucleoside triphosphate phosphatase activity structural molecule activity suppression by virus of host type I interferon production viral RNA genome replication viral protein processing virion attachment to host cell virus-mediated pore formation in host cell membrane	GO:0003723 GO:0003724 GO:0003968 GO:0004197 GO:0005198 GO:0005216 GO:0005524 GO:0006351 GO:0006417 GO:0006508 GO:0016020 GO:0017111 GO:0019062 GO:0019082 GO:0039501 GO:0039520 GO:0039525 GO:0039618 GO:0039694 GO:0039707 GO:0042025 GO:0044162 GO:0044167 GO:0051259 GO:0060090 GO:0075512
GL_002207	Genome polyprotein	Q3HNQ2		Rabbit hemorrhagic disease virus	11976	ATP binding ATP hydrolysis activity DNA-templated transcription RNA binding RNA helicase activity RNA-dependent RNA polymerase activity cysteine-type endopeptidase activity cytoplasm host cell cytoplasm membrane proteolysis viral RNA genome replication viral capsid	GO:0003723 GO:0003724 GO:0003968 GO:0004197 GO:0005524 GO:0005737 GO:0006351 GO:0006508 GO:0016020 GO:0016887 GO:0019028 GO:0030430 GO:0039694
GL_002396	Genome polyprotein	Q68T42		enterovirus D68	42789	ATP binding ATP hydrolysis activity DNA-templated transcription RNA binding RNA helicase activity RNA-dependent RNA polymerase activity T=pseudo3 icosahedral viral capsid cysteine-type endopeptidase activity cytoplasm endocytosis involved in viral entry into host cell host cell cytoplasmic vesicle membrane host cell nucleus induction by virus of host autophagy membrane metal ion binding monoatomic ion channel activity pore-mediated entry of viral genome into host cell protein complex oligomerization protein sequestering activity proteolysis structural molecule activity suppression by virus of host NF-kappaB cascade suppression by virus of host gene expression suppression by virus of host mRNA export from nucleus suppression by virus of host toll-like receptor signaling pathway suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity viral RNA genome replication virion attachment to host cell virus-mediated pore formation in host cell membrane	GO:0003723 GO:0003724 GO:0003968 GO:0004197 GO:0005198 GO:0005216 GO:0005524 GO:0005737 GO:0006351 GO:0006508 GO:0016020 GO:0016887 GO:0019062 GO:0039520 GO:0039522 GO:0039537 GO:0039554 GO:0039618 GO:0039644 GO:0039657 GO:0039694 GO:0039707 GO:0039722 GO:0042025 GO:0044162 GO:0044694 GO:0046872 GO:0051259 GO:0075509 GO:0140311
GL_001077	Ricin	P02879	Gal	Ricinus communis	3988	AMP binding carbohydrate binding defense response killing of cells of another organism negative regulation of translation rRNA N-glycosylase activity toxin activity	GO:0006952 GO:0016208 GO:0017148 GO:0030246 GO:0030598 GO:0031640 GO:0090729
GL_001643	Glycogen phosphorylase, muscle form	P09812		Rattus norvegicus	10116	AMP binding SHG alpha-glucan phosphorylase activity carbohydrate binding cytoplasm glycogen catabolic process glycogen metabolic process glycogen phosphorylase activity intracellular calcium ion homeostasis linear malto-oligosaccharide phosphorylase activity organic cyclic compound binding pyridoxal phosphate binding response to cAMP response to hypoxia response to organic substance sarcoplasmic reticulum	GO:0001666 GO:0005737 GO:0005977 GO:0005980 GO:0006874 GO:0008184 GO:0010033 GO:0016208 GO:0016529 GO:0030170 GO:0030246 GO:0051591 GO:0097159 GO:0102250 GO:0102499
GL_001644	Glycogen phosphorylase, muscle form	Q9WUB3		Mus musculus	10090	AMP binding SHG alpha-glucan phosphorylase activity Z disc carbohydrate binding cytoplasm glycogen catabolic process glycogen metabolic process glycogen phosphorylase activity intracellular calcium ion homeostasis linear malto-oligosaccharide phosphorylase activity organic cyclic compound binding pyridoxal phosphate binding response to cAMP response to hypoxia response to organic substance sarcoplasmic reticulum	GO:0001666 GO:0005737 GO:0005977 GO:0005980 GO:0006874 GO:0008184 GO:0010033 GO:0016208 GO:0016529 GO:0030018 GO:0030170 GO:0030246 GO:0051591 GO:0097159 GO:0102250 GO:0102499
GL_001675	L-arabinose-binding periplasmic protein	P02924		Escherichia coli K-12	83333	ABC-type monosaccharide transporter activity ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing L-arabinose transmembrane transport carbohydrate binding membrane monosaccharide binding outer membrane-bounded periplasmic space	GO:0015407 GO:0016020 GO:0030246 GO:0030288 GO:0042882 GO:0048029 GO:0055052
GL_001884	Uncharacterized protein YihR	P32139		Escherichia coli K-12	83333	6-sulfoquinovose(1-) catabolic process aldose 1-epimerase activity carbohydrate binding galactose catabolic process via UDP-galactose glucose metabolic process single-species biofilm formation	GO:0004034 GO:0006006 GO:0030246 GO:0033499 GO:0044010 GO:1902777
GL_001844	Sulfoquinovosidase	P32138		Escherichia coli K-12	83333	6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde carbohydrate binding carbohydrate metabolic process hydrolase activity, hydrolyzing O-glycosyl compounds sulfoquinovosidase activity	GO:0004553 GO:0005975 GO:0030246 GO:0061720 GO:1990929