GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID ▲	GO Labels	GO IDs
GL_000290	Calreticulin (Fragment)	P28490	Canis lupus familiaris	9615	calcium ion binding carbohydrate binding cell surface cortical granule cytolytic granule cytosol extracellular region protein stabilization sarcoplasmic reticulum lumen	GO:0005509 GO:0005576 GO:0005829 GO:0009986 GO:0030246 GO:0033018 GO:0044194 GO:0050821 GO:0060473
GL_001681	Laforin	Q1M199	Canis lupus familiaris	9615	autophagy carbohydrate binding carbohydrate phosphatase activity cytoplasm cytoplasmic side of rough endoplasmic reticulum membrane dephosphorylation glycogen binding glycogen metabolic process myosin phosphatase activity nucleus plasma membrane protein tyrosine phosphatase activity protein tyrosine/serine/threonine phosphatase activity starch binding	GO:0004725 GO:0005634 GO:0005737 GO:0005886 GO:0005977 GO:0006914 GO:0008138 GO:0016311 GO:0017018 GO:0019203 GO:0030246 GO:0098556 GO:2001069 GO:2001070
GL_000248	Calnexin	P24643	Canis lupus familiaris	9615	calcium ion binding carbohydrate binding clathrin-dependent endocytosis endoplasmic reticulum endoplasmic reticulum membrane melanosome presynapse protein folding synaptic vesicle endocytosis ubiquitin-dependent ERAD pathway unfolded protein binding	GO:0005509 GO:0005783 GO:0005789 GO:0006457 GO:0030246 GO:0030433 GO:0042470 GO:0048488 GO:0051082 GO:0072583 GO:0098793
GL_002075	Vesicular integral-membrane protein VIP36	P49256	Canis lupus familiaris	9615	COPI-coated vesicle COPII-coated ER to Golgi transport vesicle Golgi apparatus Golgi membrane cell surface cytoplasmic vesicle endoplasmic reticulum membrane endoplasmic reticulum to Golgi vesicle-mediated transport endoplasmic reticulum-Golgi intermediate compartment exocytic vesicle extracellular space heat shock protein binding mannose binding metal ion binding perinuclear region of cytoplasm plasma membrane positive regulation of phagocytosis protein transport retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	GO:0000139 GO:0005537 GO:0005615 GO:0005789 GO:0005793 GO:0005794 GO:0005886 GO:0006888 GO:0006890 GO:0009986 GO:0015031 GO:0030134 GO:0030137 GO:0031072 GO:0031410 GO:0046872 GO:0048471 GO:0050766 GO:0070382
GL_000050	Aggrecan core protein	Q28343	Canis lupus familiaris	9615	calcium ion binding carbohydrate binding cell adhesion central nervous system development extracellular space glial cell differentiation hyaluronic acid binding perineuronal net positive regulation of neuroblast proliferation skeletal system development synapse	GO:0001501 GO:0002052 GO:0005509 GO:0005540 GO:0005615 GO:0007155 GO:0007417 GO:0010001 GO:0030246 GO:0045202 GO:0072534
GL_001365	Beta-glucuronidase	O18835	Canis lupus familiaris	9615	beta-glucuronidase activity carbohydrate binding carbohydrate metabolic process extracellular space glucuronoside catabolic process lysosome signaling receptor binding	GO:0004566 GO:0005102 GO:0005615 GO:0005764 GO:0005975 GO:0019391 GO:0030246
GL_001897	Zona pellucida sperm-binding protein 3	P48831	Canis lupus familiaris	9615	acrosin binding binding of sperm to zona pellucida blastocyst formation carbohydrate binding collagen-containing extracellular matrix egg coat egg coat formation extracellular matrix extracellular space humoral immune response mediated by circulating immunoglobulin negative regulation of DNA-templated transcription oocyte development plasma membrane positive regulation of DNA-templated transcription positive regulation of T cell proliferation positive regulation of acrosomal vesicle exocytosis positive regulation of acrosome reaction positive regulation of antral ovarian follicle growth positive regulation of humoral immune response positive regulation of inflammatory response positive regulation of interleukin-4 production positive regulation of leukocyte migration positive regulation of ovarian follicle development positive regulation of type II interferon production positive regulation of type IV hypersensitivity receptor ligand activity structural constituent of egg coat	GO:0001809 GO:0001825 GO:0002455 GO:0002687 GO:0002922 GO:0005615 GO:0005886 GO:0007339 GO:0030246 GO:0031012 GO:0032190 GO:0032729 GO:0032753 GO:0035803 GO:0035804 GO:0035805 GO:0042102 GO:0045892 GO:0045893 GO:0048018 GO:0048599 GO:0050729 GO:0062023 GO:2000344 GO:2000368 GO:2000386 GO:2000388
GL_002004	E-selectin	P33730	Canis lupus familiaris	9615	calcium ion binding external side of plasma membrane extracellular space heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules leukocyte tethering or rolling oligosaccharide binding positive regulation of leukocyte tethering or rolling response to cytokine sialic acid binding	GO:0005509 GO:0005615 GO:0007157 GO:0009897 GO:0033691 GO:0034097 GO:0050901 GO:0070492 GO:1903238
GL_001014	Pulmonary surfactant-associated protein A	P06908	Canis lupus familiaris	9615	carbohydrate binding collagen trimer extracellular space metal ion binding multivesicular body respiratory gaseous exchange by respiratory system	GO:0005581 GO:0005615 GO:0005771 GO:0007585 GO:0030246 GO:0046872
GL_000805	Natural killer cells antigen CD94	Q38HS3	Canis lupus familiaris	9615	adaptive immune response carbohydrate binding external side of plasma membrane innate immune response negative regulation of T cell mediated cytotoxicity negative regulation of natural killer cell mediated cytotoxicity plasma membrane positive regulation of natural killer cell mediated cytotoxicity stimulatory C-type lectin receptor signaling pathway transmembrane signaling receptor activity	GO:0001915 GO:0002223 GO:0002250 GO:0004888 GO:0005886 GO:0009897 GO:0030246 GO:0045087 GO:0045953 GO:0045954