GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID	GO Labels	GO IDs ▼
GL_001231	Alpha-mannosidase 2	Q16706	Homo sapiens	9606	Golgi medial cisterna Golgi membrane N-glycan processing alpha-mannosidase activity carbohydrate binding cis-Golgi network extracellular exosome hydrolase activity, hydrolyzing N-glycosyl compounds in utero embryonic development liver development lung alveolus development mannose metabolic process mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity membrane metal ion binding mitochondrion organization positive regulation of neurogenesis protein glycosylation protein homodimerization activity respiratory gaseous exchange by respiratory system retina morphogenesis in camera-type eye vacuole organization viral protein processing	GO:0000139 GO:0001701 GO:0001889 GO:0004559 GO:0004572 GO:0005797 GO:0005801 GO:0006013 GO:0006486 GO:0006491 GO:0007005 GO:0007033 GO:0007585 GO:0016020 GO:0016799 GO:0019082 GO:0030246 GO:0042803 GO:0046872 GO:0048286 GO:0050769 GO:0060042 GO:0070062
GL_001232	Alpha-mannosidase 2	P27046	Mus musculus	10090	Golgi apparatus Golgi medial cisterna Golgi membrane N-glycan processing alpha-mannosidase activity carbohydrate binding cis-Golgi network extracellular space hydrolase activity hydrolase activity, hydrolyzing N-glycosyl compounds identical protein binding in utero embryonic development liver development lung alveolus development mannose metabolic process mannosidase activity mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity metal ion binding mitochondrion organization positive regulation of neurogenesis protein glycosylation protein homodimerization activity respiratory gaseous exchange by respiratory system retina morphogenesis in camera-type eye vacuole organization	GO:0000139 GO:0001701 GO:0001889 GO:0004559 GO:0004572 GO:0005615 GO:0005794 GO:0005797 GO:0005801 GO:0006013 GO:0006486 GO:0006491 GO:0007005 GO:0007033 GO:0007585 GO:0015923 GO:0016787 GO:0016799 GO:0030246 GO:0042802 GO:0042803 GO:0046872 GO:0048286 GO:0050769 GO:0060042
GL_001230	Alpha-mannosidase 2	P28494	Rattus norvegicus	10116	Golgi apparatus Golgi medial cisterna Golgi membrane N-glycan processing alpha-mannosidase activity carbohydrate binding cis-Golgi network extracellular space hydrolase activity hydrolase activity, hydrolyzing N-glycosyl compounds identical protein binding in utero embryonic development liver development lung alveolus development mannose metabolic process mannosidase activity mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity mitochondrion organization positive regulation of neurogenesis protein glycosylation protein homodimerization activity respiratory gaseous exchange by respiratory system retina morphogenesis in camera-type eye vacuole organization zinc ion binding	GO:0000139 GO:0001701 GO:0001889 GO:0004559 GO:0004572 GO:0005615 GO:0005794 GO:0005797 GO:0005801 GO:0006013 GO:0006486 GO:0006491 GO:0007005 GO:0007033 GO:0007585 GO:0008270 GO:0015923 GO:0016787 GO:0016799 GO:0030246 GO:0042802 GO:0042803 GO:0048286 GO:0050769 GO:0060042
GL_002347	Neural cell adhesion molecule 1	P13591	Homo sapiens	9606	Golgi membrane cell adhesion cell surface collagen-containing extracellular matrix commissural neuron axon guidance cytosol epithelial to mesenchymal transition external side of plasma membrane extracellular region membrane plasma membrane regulation of semaphorin-plexin signaling pathway virus receptor activity	GO:0000139 GO:0001618 GO:0001837 GO:0005576 GO:0005829 GO:0005886 GO:0007155 GO:0009897 GO:0009986 GO:0016020 GO:0062023 GO:0071679 GO:2001260
GL_000876	Polycystin-1	P98161	Homo sapiens	9606	Golgi apparatus Golgi membrane Golgi-associated vesicle membrane Wnt receptor activity anatomical structure morphogenesis basolateral plasma membrane branching morphogenesis of an epithelial tube calcium channel activity calcium channel complex calcium ion transmembrane transport calcium ion transport calcium-independent cell-matrix adhesion carbohydrate binding cartilage condensation cartilage development cation channel complex cell surface cell-cell signaling by wnt cell-matrix adhesion ciliary membrane cilium cytoplasm detection of mechanical stimulus digestive tract development embryonic placenta development endoplasmic reticulum establishment of epithelial cell polarity extracellular exosome genitalia development heart development homophilic cell adhesion via plasma membrane adhesion molecules in utero embryonic development kidney development lateral plasma membrane liver development lung epithelium development lymph vessel morphogenesis membrane mesonephric duct development mesonephric tubule development metanephric ascending thin limb development metanephric collecting duct development metanephric distal tubule morphogenesis metanephric proximal tubule development motile cilium neural tube development nucleus peptidyl-serine phosphorylation placenta blood vessel development plasma membrane polycystin complex positive regulation of cytosolic calcium ion concentration positive regulation of transcription by RNA polymerase II protein domain specific binding protein export from nucleus protein heterotetramerization protein kinase binding receptor signaling pathway via JAK-STAT regulation of G1/S transition of mitotic cell cycle regulation of cell adhesion regulation of cell cycle regulation of mitotic spindle organization regulation of proteasomal protein catabolic process response to fluid shear stress skin development spinal cord development transcription regulator inhibitor activity transmembrane transporter binding	GO:0000139 GO:0001502 GO:0001701 GO:0001822 GO:0001889 GO:0001892 GO:0002133 GO:0005262 GO:0005634 GO:0005737 GO:0005783 GO:0005794 GO:0005886 GO:0005929 GO:0006611 GO:0006816 GO:0007156 GO:0007160 GO:0007161 GO:0007204 GO:0007259 GO:0007507 GO:0009653 GO:0009986 GO:0016020 GO:0016323 GO:0016328 GO:0018105 GO:0019901 GO:0019904 GO:0021510 GO:0021915 GO:0030155 GO:0030246 GO:0030660 GO:0031514 GO:0034405 GO:0034703 GO:0034704 GO:0036303 GO:0042813 GO:0043588 GO:0044325 GO:0045944 GO:0048565 GO:0048754 GO:0048806 GO:0050982 GO:0051216 GO:0051290 GO:0051726 GO:0060170 GO:0060236 GO:0060428 GO:0060674 GO:0061136 GO:0070062 GO:0070588 GO:0072164 GO:0072177 GO:0072205 GO:0072218 GO:0072237 GO:0072287 GO:0090162 GO:0140416 GO:0198738 GO:2000045
GL_002052	Protein EMP47	P43555	Saccharomyces cerevisiae S288C	559292	COPII-coated ER to Golgi transport vesicle Golgi membrane carbohydrate derivative binding endoplasmic reticulum membrane endoplasmic reticulum to Golgi vesicle-mediated transport endoplasmic reticulum-Golgi intermediate compartment fungal-type vacuole membrane mannose binding	GO:0000139 GO:0000329 GO:0005537 GO:0005789 GO:0005793 GO:0006888 GO:0030134 GO:0097367
GL_001229	Alpha-mannosidase 2	Q9LFR0	Arabidopsis thaliana	3702	Golgi apparatus Golgi cis cisterna Golgi membrane alpha-mannosidase activity carbohydrate binding endosome hyperosmotic salinity response mannose metabolic process mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity metal ion binding protein N-linked glycosylation trans-Golgi network	GO:0000137 GO:0000139 GO:0004559 GO:0004572 GO:0005768 GO:0005794 GO:0005802 GO:0006013 GO:0006487 GO:0030246 GO:0042538 GO:0046872
GL_002122	Flocculin	B3IUA8	Saccharomyces pastorianus	27292	flocculation metal ion binding side of membrane	GO:0000128 GO:0046872 GO:0098552
GL_002368	Flocculation protein FLO5	P38894	Saccharomyces cerevisiae S288C	559292	cell periphery cell-substrate adhesion extracellular region flocculation fungal-type cell wall mannose binding side of membrane	GO:0000128 GO:0005537 GO:0005576 GO:0009277 GO:0031589 GO:0071944 GO:0098552
GL_002364	Flocculation protein FLO1	P32768	Saccharomyces cerevisiae S288C	559292	cell periphery extracellular region flocculation fungal-type cell wall mannose binding plasma membrane side of membrane	GO:0000128 GO:0005537 GO:0005576 GO:0005886 GO:0009277 GO:0071944 GO:0098552