GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID	GO Labels ▼	GO IDs
GL_001190	4-alpha-glucanotransferase	O32450	Thermococcus kodakarensis KOD1	69014	4-alpha-glucanotransferase activity beta-maltose 4-alpha-glucanotransferase activity carbohydrate binding carbohydrate metabolic process	GO:0004134 GO:0005975 GO:0030246 GO:0102500
GL_001189	4-alpha-glucanotransferase	O32462	Thermococcus litoralis DSM 5473	523849	4-alpha-glucanotransferase activity beta-maltose 4-alpha-glucanotransferase activity carbohydrate binding carbohydrate metabolic process	GO:0004134 GO:0005975 GO:0030246 GO:0102500
GL_001503	Galactose-3-O-sulfotransferase 3	Q96A11	Homo sapiens	9606	3'-phosphoadenosine 5'-phosphosulfate binding Golgi cisterna membrane carbohydrate binding galactose 3-O-sulfotransferase activity galactosylceramide sulfotransferase activity glycolipid biosynthetic process membrane monosaccharide metabolic process oligosaccharide metabolic process poly-N-acetyllactosamine metabolic process proteoglycan biosynthetic process proteoglycan sulfotransferase activity sulfur compound metabolic process	GO:0001733 GO:0005996 GO:0006790 GO:0009247 GO:0009311 GO:0016020 GO:0030166 GO:0030246 GO:0030309 GO:0032580 GO:0050656 GO:0050694 GO:0050698
GL_001731	Nigerose phosphorylase	A9KT32	Lachnoclostridium phytofermentans ISDg	357809	1,4-alpha-oligoglucan phosphorylase activity carbohydrate binding carbohydrate metabolic process cytoplasm	GO:0004645 GO:0005737 GO:0005975 GO:0030246
GL_001184	1,4-alpha-glucan-branching enzyme	Q9D6Y9	Mus musculus	10090	1,4-alpha-glucan branching enzyme activity 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) carbohydrate binding cation binding cytoplasm cytosol glycogen biosynthetic process hydrolase activity, hydrolyzing O-glycosyl compounds negative regulation of neuron apoptotic process	GO:0003844 GO:0004553 GO:0005737 GO:0005829 GO:0005978 GO:0030246 GO:0043169 GO:0043524 GO:0102752
GL_001183	1,4-alpha-glucan-branching enzyme	Q04446	Homo sapiens	9606	1,4-alpha-glucan branching enzyme activity 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) carbohydrate binding cation binding cytoplasm cytosol extracellular exosome generation of precursor metabolites and energy glycogen biosynthetic process glycogen metabolic process hydrolase activity, hydrolyzing O-glycosyl compounds negative regulation of neuron apoptotic process	GO:0003844 GO:0004553 GO:0005737 GO:0005829 GO:0005977 GO:0005978 GO:0006091 GO:0030246 GO:0043169 GO:0043524 GO:0070062 GO:0102752
GL_001835	Sorbitol dehydrogenase	Q00796	Homo sapiens	9606	(R,R)-butanediol dehydrogenase activity D-sorbitol dehydrogenase (acceptor) activity D-xylulose reductase activity L-iditol 2-dehydrogenase activity L-xylitol catabolic process L-xylitol metabolic process NAD binding carbohydrate binding cytosol extracellular exosome extracellular space flagellated sperm motility fructose biosynthetic process glucose metabolic process glucuronate catabolic process to xylulose 5-phosphate identical protein binding membrane mitochondrial membrane motile cilium ribitol 2-dehydrogenase activity sorbitol catabolic process zinc ion binding	GO:0000721 GO:0003939 GO:0005615 GO:0005829 GO:0006006 GO:0006062 GO:0008270 GO:0016020 GO:0019640 GO:0030246 GO:0030317 GO:0031514 GO:0031966 GO:0042802 GO:0046370 GO:0046526 GO:0047833 GO:0050255 GO:0051160 GO:0051164 GO:0051287 GO:0070062
GL_001832	Secreted beta-glucosidase sun1	Q4WGL5	Aspergillus fumigatus Af293	330879	(1->3)-beta-D-glucan catabolic process carbohydrate binding cell surface extracellular region fungal-type cell wall fungal-type cell wall organization hydrolase activity, acting on glycosyl bonds hyphal growth	GO:0005576 GO:0006076 GO:0009277 GO:0009986 GO:0016798 GO:0030246 GO:0030448 GO:0031505
GL_002359	Pentraxin-related protein PTX3	P26022	Homo sapiens	9606	(1->3)-beta-D-glucan binding complement component C1q complex binding extracellular matrix extracellular matrix organization extracellular region extracellular space identical protein binding inflammatory response innate immune response negative regulation by host of viral exo-alpha-sialidase activity negative regulation by host of viral glycoprotein metabolic process negative regulation by host of viral process negative regulation of exo-alpha-sialidase activity negative regulation of glycoprotein metabolic process negative regulation of viral entry into host cell opsonization ovarian cumulus expansion positive regulation of nitric oxide biosynthetic process positive regulation of phagocytosis response to yeast specific granule lumen tertiary granule lumen virion binding	GO:0001550 GO:0001849 GO:0001872 GO:0001878 GO:0005576 GO:0005615 GO:0006954 GO:0008228 GO:0030198 GO:0031012 GO:0035580 GO:0042802 GO:0044793 GO:0044869 GO:0044871 GO:0045087 GO:0045429 GO:0046597 GO:0046790 GO:0050766 GO:1903016 GO:1903019 GO:1904724
GL_001995	C-type lectin domain family 7 member A	Q8HZR8	Macaca mulatta	9544	(1->3)-beta-D-glucan binding antifungal innate immune response cell surface cellular response to molecule of fungal origin detection of fungus detection of molecule of fungal origin inflammatory response metal ion binding pattern recognition receptor activity phagocytosis, recognition plasma membrane positive regulation of T-helper 17 type immune response positive regulation of canonical NF-kappaB signal transduction positive regulation of cell migration positive regulation of cell population proliferation positive regulation of cytokine production involved in inflammatory response positive regulation of killing of cells of another organism positive regulation of lymphocyte activation positive regulation of phagocytosis positive regulation of wound healing	GO:0001872 GO:0005886 GO:0006910 GO:0006954 GO:0008284 GO:0009986 GO:0016046 GO:0030335 GO:0032491 GO:0038187 GO:0043123 GO:0046872 GO:0050766 GO:0051251 GO:0051712 GO:0061760 GO:0071226 GO:0090303 GO:1900017 GO:2000318