GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID ▲	GO Labels	GO IDs
GL_000503	Galectin-4	Q3T0D6	Bos taurus	9913	carbohydrate binding	GO:0030246
GL_001696	Lysosomal alpha-mannosidase	Q29451	Bos taurus	9913	alpha-mannosidase activity carbohydrate binding extracellular space learning or memory lysosomal lumen lysosome mannose metabolic process nucleoplasm oligosaccharide catabolic process protein modification process zinc ion binding	GO:0004559 GO:0005615 GO:0005654 GO:0005764 GO:0006013 GO:0007611 GO:0008270 GO:0009313 GO:0030246 GO:0036211 GO:0043202
GL_000988	Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1	Q5EAB6	Bos taurus	9913	Golgi membrane O-glycan processing acetylglucosaminyltransferase activity beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity carbohydrate binding manganese ion binding membrane protein O-linked glycosylation	GO:0000139 GO:0006493 GO:0008375 GO:0016020 GO:0016266 GO:0030145 GO:0030246 GO:0047223
GL_001256	Annexin A4	P13214	Bos taurus	9913	NF-kappaB binding Notch signaling pathway apical plasma membrane calcium ion binding calcium-dependent phospholipid binding calcium-dependent protein binding carbohydrate binding cell surface chondroitin sulfate binding chromaffin granule membrane cytoplasm cytosol epithelial cell differentiation heparin binding identical protein binding membrane negative regulation of interleukin-8 production nuclear membrane nucleus perinuclear region of cytoplasm regulation of transcription by RNA polymerase II zymogen granule membrane	GO:0005509 GO:0005544 GO:0005634 GO:0005737 GO:0005829 GO:0006357 GO:0007219 GO:0008201 GO:0009986 GO:0016020 GO:0016324 GO:0030246 GO:0030855 GO:0031965 GO:0032717 GO:0035374 GO:0042584 GO:0042589 GO:0042802 GO:0048306 GO:0048471 GO:0051059
GL_000392	Ficolin-2	Q5I2E5	Bos taurus	9913	antigen binding carbohydrate binding carbohydrate derivative binding collagen trimer collagen-containing extracellular matrix complement activation, lectin pathway extracellular space metal ion binding signaling receptor binding	GO:0001867 GO:0003823 GO:0005102 GO:0005581 GO:0005615 GO:0030246 GO:0046872 GO:0062023 GO:0097367
GL_000803	Natural killer cells antigen CD94	Q863H3	Bos taurus	9913	adaptive immune response carbohydrate binding external side of plasma membrane innate immune response negative regulation of T cell mediated cytotoxicity negative regulation of natural killer cell mediated cytotoxicity plasma membrane positive regulation of natural killer cell mediated cytotoxicity stimulatory C-type lectin receptor signaling pathway transmembrane signaling receptor activity	GO:0001915 GO:0002223 GO:0002250 GO:0004888 GO:0005886 GO:0009897 GO:0030246 GO:0045087 GO:0045953 GO:0045954
GL_001695	Lysosomal alpha-glucosidase	Q9MYM4	Bos taurus	9913	alpha-1,4-glucosidase activity aorta development autolysosome lumen carbohydrate binding cardiac muscle contraction diaphragm contraction glycogen catabolic process glycophagy heart morphogenesis locomotory behavior lysosomal membrane lysosome organization maltose alpha-glucosidase activity muscle cell cellular homeostasis neuromuscular process controlling balance neuromuscular process controlling posture regulation of the force of heart contraction tissue development vacuolar sequestering	GO:0002026 GO:0002086 GO:0003007 GO:0004558 GO:0005765 GO:0005980 GO:0007040 GO:0007626 GO:0009888 GO:0030246 GO:0032450 GO:0035904 GO:0043181 GO:0046716 GO:0050884 GO:0050885 GO:0060048 GO:0061723 GO:0120282
GL_002342	Cation-dependent mannose-6-phosphate receptor	P11456	Bos taurus	9913	Golgi apparatus endosome lysosomal membrane lysosomal transport protein domain specific binding protein targeting to lysosome trans-Golgi network	GO:0005765 GO:0005768 GO:0005794 GO:0005802 GO:0006622 GO:0007041 GO:0019904
GL_001089	Secretory phospholipase A2 receptor	P49259	Bos taurus	9913	carbohydrate binding cell surface extracellular region oxidative stress-induced premature senescence phospholipase binding plasma membrane positive regulation of DNA damage response, signal transduction by p53 class mediator positive regulation of arachidonic acid secretion positive regulation of cytokine production positive regulation of podocyte apoptotic process reactive oxygen species metabolic process receptor complex receptor-mediated endocytosis replicative senescence signaling receptor activity	GO:0001819 GO:0005576 GO:0005886 GO:0006898 GO:0009986 GO:0030246 GO:0038023 GO:0043235 GO:0043274 GO:0043517 GO:0072593 GO:0090238 GO:0090399 GO:0090403 GO:1904635
GL_002049	P-selectin	P42201	Bos taurus	9913	calcium ion binding calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules external side of plasma membrane extracellular space heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules leukocyte tethering or rolling oligosaccharide binding plasma membrane positive regulation of leukocyte tethering or rolling response to cytokine sialic acid binding	GO:0005509 GO:0005615 GO:0005886 GO:0007157 GO:0009897 GO:0016339 GO:0033691 GO:0034097 GO:0050901 GO:0070492 GO:1903238