GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID ▼	GO Labels	GO IDs
GL_002061	Pulmonary surfactant-associated protein D	P50404	Mus musculus	10090	collagen trimer collagen-containing extracellular matrix cytoplasm extracellular space identical protein binding innate immune response lipopolysaccharide binding lung alveolus development monosaccharide binding multivesicular body negative regulation of T cell proliferation negative regulation of interleukin-2 production negative regulation of phagocytosis opsonization positive regulation of phagocytosis respiratory gaseous exchange by respiratory system surfactant homeostasis	GO:0001530 GO:0005581 GO:0005615 GO:0005737 GO:0005771 GO:0007585 GO:0008228 GO:0032703 GO:0042130 GO:0042802 GO:0043129 GO:0045087 GO:0048029 GO:0048286 GO:0050765 GO:0050766 GO:0062023
GL_000252	Calnexin	P35564	Mus musculus	10090	apolipoprotein binding axon calcium ion binding carbohydrate binding clathrin-dependent endocytosis dendrite cytoplasm dendritic spine endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum quality control compartment glutamatergic synapse ionotropic glutamate receptor binding lumenal side of endoplasmic reticulum membrane melanosome membrane mitochondria-associated endoplasmic reticulum membrane myelin sheath neuronal cell body nuclear membrane postsynaptic membrane presynaptic active zone membrane protein folding protein-containing complex ribosome smooth endoplasmic reticulum synaptic vesicle endocytosis ubiquitin-dependent ERAD pathway unfolded protein binding	GO:0005509 GO:0005783 GO:0005789 GO:0005790 GO:0005840 GO:0006457 GO:0016020 GO:0030246 GO:0030424 GO:0030433 GO:0031965 GO:0032839 GO:0032991 GO:0034185 GO:0035255 GO:0042470 GO:0043025 GO:0043197 GO:0043209 GO:0044233 GO:0044322 GO:0045211 GO:0048488 GO:0048787 GO:0051082 GO:0072583 GO:0098553 GO:0098978
GL_001381	Cartilage intermediate layer protein 2	D3Z7H8	Mus musculus	10090	carbohydrate binding extracellular space	GO:0005615 GO:0030246
GL_000398	FRAS1-related extracellular matrix protein 1	Q684R7	Mus musculus	10090	anatomical structure morphogenesis basement membrane carbohydrate binding cell communication cell-matrix adhesion collagen-containing extracellular matrix craniofacial suture morphogenesis extracellular region membrane metal ion binding	GO:0005576 GO:0005604 GO:0007154 GO:0007160 GO:0009653 GO:0016020 GO:0030246 GO:0046872 GO:0062023 GO:0097094
GL_000607	Killer cell lectin-like receptor 6	Q60653	Mus musculus	10090	carbohydrate binding cell adhesion plasma membrane	GO:0005886 GO:0007155 GO:0030246
GL_000141	C-type lectin domain family 11 member A	O88200	Mus musculus	10090	carbohydrate binding cytoplasm extracellular region extracellular space growth factor activity ossification positive regulation of cell population proliferation	GO:0001503 GO:0005576 GO:0005615 GO:0005737 GO:0008083 GO:0008284 GO:0030246
GL_000905	Polypeptide N-acetylgalactosaminyltransferase 16	Q9JJ61	Mus musculus	10090	Golgi apparatus Golgi membrane carbohydrate binding metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation protein O-linked glycosylation via serine protein O-linked glycosylation via threonine	GO:0000139 GO:0004653 GO:0005794 GO:0006493 GO:0018242 GO:0018243 GO:0030246 GO:0046872
GL_001830	Sclerostin	Q99P68	Mus musculus	10090	BMP binding BMP signaling pathway DNA-binding transcription factor binding Golgi apparatus canonical Wnt signaling pathway carbohydrate binding cellular response to parathyroid hormone stimulus extracellular space heparin binding localization molecular function inhibitor activity negative regulation of BMP signaling pathway negative regulation of Wnt signaling pathway negative regulation of canonical Wnt signaling pathway negative regulation of ossification negative regulation of protein-containing complex assembly ossification positive regulation of DNA-templated transcription protein-containing complex response to mechanical stimulus	GO:0001503 GO:0005615 GO:0005794 GO:0008201 GO:0009612 GO:0030178 GO:0030246 GO:0030279 GO:0030509 GO:0030514 GO:0031333 GO:0032991 GO:0036122 GO:0045893 GO:0051179 GO:0060070 GO:0071374 GO:0090090 GO:0140297 GO:0140678
GL_000986	Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1	Q91X88	Mus musculus	10090	Golgi membrane O-glycan processing acetylglucosaminyltransferase activity basement membrane organization beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity brain development carbohydrate binding dentate gyrus development gene expression localization of cell manganese ion binding membrane myelination protein O-linked glycosylation protein O-linked mannosylation protein glycosylation protein modification process reactive gliosis sensory perception of sound	GO:0000139 GO:0006486 GO:0006493 GO:0007420 GO:0007605 GO:0008375 GO:0010467 GO:0016020 GO:0016266 GO:0021542 GO:0030145 GO:0030246 GO:0035269 GO:0036211 GO:0042552 GO:0047223 GO:0051674 GO:0071711 GO:0150103
GL_000896	Polypeptide N-acetylgalactosaminyltransferase 12	Q8BGT9	Mus musculus	10090	Golgi apparatus Golgi membrane carbohydrate binding metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation	GO:0000139 GO:0004653 GO:0005794 GO:0006493 GO:0030246 GO:0046872