GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID	GO Labels	GO IDs
GL_000266	Calreticulin	P83003	Entamoeba histolytica HM-1:IMSS	294381	calcium ion binding carbohydrate binding cell surface complement component C1q complex binding cytosol endoplasmic reticulum endoplasmic reticulum lumen evasion of host immune response via modulation of host complement system host cell surface binding phagocytic cup positive regulation of phagocytosis protein export from nucleus protein folding unfolded protein binding uropod	GO:0001849 GO:0001891 GO:0001931 GO:0005509 GO:0005783 GO:0005788 GO:0005829 GO:0006457 GO:0006611 GO:0009986 GO:0030246 GO:0042784 GO:0046812 GO:0050766 GO:0051082
GL_000327	Collectin-12	A6QP79	Bos taurus	9913	carbohydrate binding collagen trimer collagen-containing extracellular matrix extracellular space low-density lipoprotein particle binding membrane metal ion binding pattern recognition receptor activity phagocytosis, recognition	GO:0005581 GO:0005615 GO:0006910 GO:0016020 GO:0030169 GO:0030246 GO:0038187 GO:0046872 GO:0062023
GL_001694	Lysosomal alpha-glucosidase	Q6P7A9	Rattus norvegicus	10116	alpha-1,4-glucosidase activity alpha-glucosidase activity aorta development autolysosome lumen carbohydrate binding cardiac muscle contraction diaphragm contraction glycogen catabolic process glycogen metabolic process glycophagy heart morphogenesis locomotory behavior lysosomal membrane lysosome lysosome organization maltose alpha-glucosidase activity membrane muscle cell cellular homeostasis neuromuscular process controlling balance neuromuscular process controlling posture regulation of the force of heart contraction striated muscle contraction tissue development vacuolar sequestering	GO:0002026 GO:0002086 GO:0003007 GO:0004558 GO:0005764 GO:0005765 GO:0005977 GO:0005980 GO:0006941 GO:0007040 GO:0007626 GO:0009888 GO:0016020 GO:0030246 GO:0032450 GO:0035904 GO:0043181 GO:0046716 GO:0050884 GO:0050885 GO:0060048 GO:0061723 GO:0090599 GO:0120282
GL_001248	Alpha-xylosidase	Q9P999	Saccharolobus solfataricus P2	273057	alpha-D-xyloside xylohydrolase carbohydrate binding carbohydrate metabolic process	GO:0005975 GO:0030246 GO:0061634
GL_002381	Lectin OAA	P84330	Planktothrix agardhii	1160	mannose binding	GO:0005537
GL_001051	Putative L-type lectin-domain containing receptor kinase V.2	O04533	Arabidopsis thaliana	3702	ATP binding carbohydrate binding phosphorylation plasma membrane protein serine kinase activity protein serine/threonine kinase activity response to stimulus	GO:0004674 GO:0005524 GO:0005886 GO:0016310 GO:0030246 GO:0050896 GO:0106310
GL_002160	Genome polyprotein	F5BXG7	Rabbit hemorrhagic disease virus	11976	ATP binding DNA-templated transcription RNA binding RNA helicase activity RNA-dependent RNA polymerase activity cysteine-type endopeptidase activity cytoplasm host cell cytoplasm membrane proteolysis ribonucleoside triphosphate phosphatase activity viral RNA genome replication viral capsid	GO:0003723 GO:0003724 GO:0003968 GO:0004197 GO:0005524 GO:0005737 GO:0006351 GO:0006508 GO:0016020 GO:0017111 GO:0019028 GO:0030430 GO:0039694
GL_001134	Struthiocalcin-2	P83515	Struthio camelus	8801	carbohydrate binding extracellular region	GO:0005576 GO:0030246
GL_001891	Zona pellucida sperm-binding protein 3	P21754	Homo sapiens	9606	acrosin binding binding of sperm to zona pellucida blastocyst formation carbohydrate binding collagen-containing extracellular matrix egg coat egg coat formation extracellular matrix extracellular matrix structural constituent extracellular region extracellular space humoral immune response mediated by circulating immunoglobulin identical protein binding negative regulation of DNA-templated transcription negative regulation of binding of sperm to zona pellucida oocyte development plasma membrane positive regulation of DNA-templated transcription positive regulation of T cell proliferation positive regulation of acrosomal vesicle exocytosis positive regulation of acrosome reaction positive regulation of antral ovarian follicle growth positive regulation of humoral immune response positive regulation of inflammatory response positive regulation of interleukin-4 production positive regulation of leukocyte migration positive regulation of ovarian follicle development positive regulation of type II interferon production positive regulation of type IV hypersensitivity receptor ligand activity structural constituent of egg coat	GO:0001809 GO:0001825 GO:0002455 GO:0002687 GO:0002922 GO:0005201 GO:0005576 GO:0005615 GO:0005886 GO:0007339 GO:0030246 GO:0031012 GO:0032190 GO:0032729 GO:0032753 GO:0035803 GO:0035804 GO:0035805 GO:0042102 GO:0042802 GO:0045892 GO:0045893 GO:0048018 GO:0048599 GO:0050729 GO:0062023 GO:2000344 GO:2000360 GO:2000368 GO:2000386 GO:2000388
GL_000255	Calnexin homolog	Q6Q487	Aspergillus fumigatus Af293	330879	calcium ion binding carbohydrate binding cellular response to heat cellular response to starvation endoplasmic reticulum membrane protein folding ubiquitin-dependent ERAD pathway unfolded protein binding	GO:0005509 GO:0005789 GO:0006457 GO:0009267 GO:0030246 GO:0030433 GO:0034605 GO:0051082