GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID	GO Labels ▲	GO IDs
GL_000182	C-type lectin domain family 4 member E	Q9R0Q8	Mus musculus	10090	Fc-gamma receptor signaling pathway T cell differentiation involved in immune response antifungal innate immune response calcium ion binding carbohydrate binding cell projection defense response to bacterium external side of plasma membrane glycolipid binding immune response innate immune response membrane pattern recognition receptor activity pattern recognition receptor signaling pathway phagocytic cup phagocytic vesicle membrane plasma membrane positive regulation of cytokine production signaling receptor activity	GO:0001819 GO:0001891 GO:0002221 GO:0002292 GO:0005509 GO:0005886 GO:0006955 GO:0009897 GO:0016020 GO:0030246 GO:0030670 GO:0038023 GO:0038094 GO:0038187 GO:0042742 GO:0042995 GO:0045087 GO:0051861 GO:0061760
GL_000181	C-type lectin domain family 4 member E	Q67EQ1	Rattus norvegicus	10116	Fc-gamma receptor signaling pathway T cell differentiation involved in immune response antifungal innate immune response calcium ion binding carbohydrate binding cell projection defense response to bacterium external side of plasma membrane glycolipid binding immune response innate immune response membrane pattern recognition receptor activity pattern recognition receptor signaling pathway phagocytic cup phagocytic vesicle membrane plasma membrane positive regulation of cytokine production signaling receptor activity	GO:0001819 GO:0001891 GO:0002221 GO:0002292 GO:0005509 GO:0005886 GO:0006955 GO:0009897 GO:0016020 GO:0030246 GO:0030670 GO:0038023 GO:0038094 GO:0038187 GO:0042742 GO:0042995 GO:0045087 GO:0051861 GO:0061760
GL_000180	C-type lectin domain family 4 member E	Q9ULY5	Homo sapiens	9606	Fc-gamma receptor signaling pathway T cell differentiation involved in immune response antifungal innate immune response calcium ion binding carbohydrate binding cell projection defense response to bacterium external side of plasma membrane glycolipid binding innate immune response membrane pattern recognition receptor activity pattern recognition receptor signaling pathway phagocytic cup phagocytic vesicle membrane plasma membrane positive regulation of cytokine production	GO:0001819 GO:0001891 GO:0002221 GO:0002292 GO:0005509 GO:0005886 GO:0009897 GO:0016020 GO:0030246 GO:0030670 GO:0038094 GO:0038187 GO:0042742 GO:0042995 GO:0045087 GO:0051861 GO:0061760
GL_001925	C-type lectin domain family 4 member E	E1BHM0	Bos taurus	9913	Fc-gamma receptor signaling pathway T cell differentiation involved in immune response antifungal innate immune response calcium ion binding carbohydrate binding defense response to bacterium external side of plasma membrane glycolipid binding pattern recognition receptor activity pattern recognition receptor signaling pathway phagocytic vesicle membrane positive regulation of cytokine production	GO:0001819 GO:0002221 GO:0002292 GO:0005509 GO:0009897 GO:0030246 GO:0030670 GO:0038094 GO:0038187 GO:0042742 GO:0051861 GO:0061760
GL_000353	Doublecortin domain-containing protein 1	M0R2J8	Homo sapiens	9606	Flemming body carbohydrate binding cell cycle cell division cytoplasm intracellular signal transduction microtubule microtubule binding midbody mitotic spindle regulation of mitotic cytokinesis	GO:0005737 GO:0005874 GO:0007049 GO:0008017 GO:0030246 GO:0030496 GO:0035556 GO:0051301 GO:0072686 GO:0090543 GO:1902412
GL_001417	Contactin-2	P22063	Rattus norvegicus	10116	G protein-coupled adenosine receptor signaling pathway adult walking behavior axon axon guidance axon initial segment axonal fasciculation axonogenesis brain development carbohydrate binding cell surface cell-cell adhesion cell-cell adhesion mediator activity cell-matrix adhesion central nervous system myelination cerebral cortex GABAergic interneuron migration clustering of voltage-gated potassium channels establishment of localization in cell establishment of protein localization to juxtaparanode region of axon fat cell differentiation juxtaparanode region of axon learning microtubule cytoskeleton organization myelin sheath negative regulation of neuron differentiation neuron differentiation neuron migration neuron projection neuron projection development neuronal cell body node of Ranvier plasma membrane positive regulation of adenosine receptor signaling pathway positive regulation of protein processing postsynaptic membrane presynaptic membrane organization protein localization to juxtaparanode region of axon protein processing protein self-association receptor internalization reduction of food intake in response to dietary excess regulation of astrocyte differentiation regulation of axon diameter regulation of cell morphogenesis regulation of neuronal synaptic plasticity response to dietary excess side of membrane synapse	GO:0000226 GO:0001764 GO:0001973 GO:0002021 GO:0002023 GO:0005886 GO:0007160 GO:0007409 GO:0007411 GO:0007413 GO:0007420 GO:0007612 GO:0007628 GO:0009986 GO:0010954 GO:0016485 GO:0021853 GO:0022010 GO:0022604 GO:0030182 GO:0030246 GO:0030424 GO:0031133 GO:0031175 GO:0031623 GO:0033268 GO:0043005 GO:0043025 GO:0043194 GO:0043209 GO:0043621 GO:0044224 GO:0045163 GO:0045202 GO:0045211 GO:0045444 GO:0045665 GO:0048168 GO:0048710 GO:0051649 GO:0060168 GO:0071205 GO:0071206 GO:0097090 GO:0098552 GO:0098609 GO:0098632
GL_000022	Adhesion G protein-coupled receptor L3	Q9HAR2	Homo sapiens	9606	G protein-coupled receptor activity G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway axon calcium ion binding carbohydrate binding cell surface receptor signaling pathway cell-cell adhesion via plasma-membrane adhesion molecules cell-cell junction glutamatergic synapse membrane neuron migration plasma membrane synapse assembly	GO:0001764 GO:0004930 GO:0005509 GO:0005886 GO:0005911 GO:0007166 GO:0007186 GO:0007189 GO:0007416 GO:0016020 GO:0030246 GO:0030424 GO:0098742 GO:0098978
GL_000017	Adhesion G protein-coupled receptor L1	O94910	Homo sapiens	9606	G protein-coupled receptor activity G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway axon calcium-mediated signaling using intracellular calcium source carbohydrate binding cell adhesion molecule binding cell surface receptor signaling pathway growth cone heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules latrotoxin receptor activity membrane neuron projection plasma membrane positive regulation of synapse maturation presynaptic membrane synapse	GO:0004930 GO:0005886 GO:0007157 GO:0007166 GO:0007186 GO:0007189 GO:0016020 GO:0016524 GO:0030246 GO:0030424 GO:0030426 GO:0035584 GO:0042734 GO:0043005 GO:0045202 GO:0050839 GO:0090129
GL_000020	Adhesion G protein-coupled receptor L2	O95490	Homo sapiens	9606	G protein-coupled receptor activity G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway carbohydrate binding cell surface receptor signaling pathway latrotoxin receptor activity membrane	GO:0004930 GO:0007166 GO:0007186 GO:0007189 GO:0016020 GO:0016524 GO:0030246
GL_001195	Adhesion G protein-coupled receptor L2	Q8JZZ7	Mus musculus	10090	G protein-coupled receptor activity PDZ domain binding adenylate cyclase-activating G protein-coupled receptor signaling pathway carbohydrate binding cell surface receptor signaling pathway glutamatergic synapse positive regulation of synapse assembly postsynaptic membrane response to bacterium synapse organization	GO:0004930 GO:0007166 GO:0007189 GO:0009617 GO:0030165 GO:0030246 GO:0045211 GO:0050808 GO:0051965 GO:0098978