GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database Last Updated
MCAW-DB July 10, 2019
UniLectin June 14, 2023
UniProt February 16, 2024
Lectin Frontier DataBase (LfDB) February 16, 2024
CarboGrove June 14, 2023
GlyCosmos Lectin Lectin Name UniProt ID Monosaccharide Specificities Species Taxonomy ID ▼ GO Labels GO IDs
Chitinase-like protein 3
10090
  • N-acetyl-beta-D-galactosaminidase activity
  • beta-N-acetylhexosaminidase activity
  • carbohydrate binding
  • chitin binding
  • chitin catabolic process
  • cytoplasm
  • cytoplasmic vesicle
  • extracellular region
  • extracellular space
  • inflammatory response
  • kinase binding
  • nuclear envelope
  • polysaccharide catabolic process
  • positive regulation of chemokine production
  • production of molecular mediator involved in inflammatory response
  • rough endoplasmic reticulum lumen
  • GO:0000272
  • GO:0002532
  • GO:0004563
  • GO:0005576
  • GO:0005615
  • GO:0005635
  • GO:0005737
  • GO:0006032
  • GO:0006954
  • GO:0008061
  • GO:0019900
  • GO:0030246
  • GO:0031410
  • GO:0032722
  • GO:0048237
  • GO:0102148
Galectin-related protein
10090
  • carbohydrate binding
  • collagen-containing extracellular matrix
  • GO:0030246
  • GO:0062023
Neurocan core protein
10090
  • GABA-ergic synapse
  • calcium ion binding
  • carbohydrate binding
  • cell adhesion
  • central nervous system development
  • extracellular space
  • glial cell differentiation
  • glutamatergic synapse
  • hyaluronic acid binding
  • modulation of chemical synaptic transmission
  • perineuronal net
  • perisynaptic extracellular matrix
  • plasma membrane
  • positive regulation of neuroblast proliferation
  • regulation of postsynapse organization
  • regulation of synapse structural plasticity
  • skeletal system development
  • synapse
  • GO:0001501
  • GO:0002052
  • GO:0005509
  • GO:0005540
  • GO:0005615
  • GO:0005886
  • GO:0007155
  • GO:0007417
  • GO:0010001
  • GO:0030246
  • GO:0045202
  • GO:0050804
  • GO:0051823
  • GO:0072534
  • GO:0098966
  • GO:0098978
  • GO:0098982
  • GO:0099175
CD209 antigen-like protein A
10090
  • B cell adhesion
  • calcium-dependent protein binding
  • carbohydrate binding
  • carbohydrate derivative binding
  • cell surface
  • endocytosis
  • external side of plasma membrane
  • immune response
  • mannose binding
  • membrane
  • metal ion binding
  • plasma membrane
  • positive regulation of T cell proliferation
  • positive regulation of viral life cycle
  • regulation of T cell proliferation
  • viral entry into host cell
  • virus receptor activity
  • GO:0001618
  • GO:0005537
  • GO:0005886
  • GO:0006897
  • GO:0006955
  • GO:0009897
  • GO:0009986
  • GO:0016020
  • GO:0030246
  • GO:0042102
  • GO:0042129
  • GO:0046718
  • GO:0046872
  • GO:0048306
  • GO:0097323
  • GO:0097367
  • GO:1903902
Calreticulin
10090
  • MHC class I peptide loading complex
  • acrosomal vesicle
  • calcium ion binding
  • carbohydrate binding
  • cardiac muscle cell differentiation
  • cell surface
  • cellular response to electrical stimulus
  • cellular response to lithium ion
  • cellular response to organic substance
  • cellular response to virus
  • cellular senescence
  • collagen-containing extracellular matrix
  • complement component C1q complex binding
  • cortical actin cytoskeleton organization
  • cortical granule
  • cytolytic granule
  • cytoplasm
  • cytosol
  • endoplasmic reticulum
  • endoplasmic reticulum lumen
  • endoplasmic reticulum membrane
  • endoplasmic reticulum quality control compartment
  • external side of plasma membrane
  • extracellular region
  • extracellular space
  • hormone binding
  • integrin binding
  • iron ion binding
  • mRNA binding
  • membrane
  • negative regulation of DNA-templated transcription
  • negative regulation of intracellular steroid hormone receptor signaling pathway
  • negative regulation of neuron differentiation
  • negative regulation of retinoic acid receptor signaling pathway
  • negative regulation of transcription by RNA polymerase II
  • negative regulation of translation
  • negative regulation of trophoblast cell migration
  • nuclear androgen receptor binding
  • nuclear envelope
  • nuclear export signal receptor activity
  • nucleus
  • obsolete selective autophagy
  • peptide antigen assembly with MHC class I protein complex
  • peptide binding
  • perinuclear region of cytoplasm
  • phagocytic vesicle
  • polysome
  • positive regulation of cell cycle
  • positive regulation of cell population proliferation
  • positive regulation of dendritic cell chemotaxis
  • positive regulation of endothelial cell migration
  • positive regulation of gene expression
  • positive regulation of non-canonical NF-kappaB signal transduction
  • positive regulation of phagocytosis
  • positive regulation of substrate adhesion-dependent cell spreading
  • protein export from nucleus
  • protein folding
  • protein localization to nucleus
  • protein stabilization
  • protein-containing complex
  • regulation of meiotic nuclear division
  • response to estradiol
  • response to glycoside
  • response to testosterone
  • response to xenobiotic stimulus
  • sarcoplasmic reticulum
  • sarcoplasmic reticulum lumen
  • smooth endoplasmic reticulum
  • spermatogenesis
  • ubiquitin protein ligase binding
  • ubiquitin-dependent ERAD pathway
  • unfolded protein binding
  • GO:0000122
  • GO:0001669
  • GO:0001849
  • GO:0002502
  • GO:0003729
  • GO:0005049
  • GO:0005178
  • GO:0005506
  • GO:0005509
  • GO:0005576
  • GO:0005615
  • GO:0005634
  • GO:0005635
  • GO:0005737
  • GO:0005783
  • GO:0005788
  • GO:0005789
  • GO:0005790
  • GO:0005829
  • GO:0005844
  • GO:0006457
  • GO:0006611
  • GO:0007283
  • GO:0008284
  • GO:0009410
  • GO:0009897
  • GO:0009986
  • GO:0010595
  • GO:0010628
  • GO:0016020
  • GO:0016529
  • GO:0017148
  • GO:0030246
  • GO:0030433
  • GO:0030866
  • GO:0031625
  • GO:0032355
  • GO:0032991
  • GO:0033018
  • GO:0033144
  • GO:0033574
  • GO:0034504
  • GO:0040020
  • GO:0042277
  • GO:0042562
  • GO:0042824
  • GO:0044194
  • GO:0044322
  • GO:0045335
  • GO:0045665
  • GO:0045787
  • GO:0045892
  • GO:0048387
  • GO:0048471
  • GO:0050681
  • GO:0050766
  • GO:0050821
  • GO:0051082
  • GO:0055007
  • GO:0060473
  • GO:0061912
  • GO:0062023
  • GO:0071257
  • GO:0071285
  • GO:0071310
  • GO:0090398
  • GO:0098586
  • GO:1900026
  • GO:1901164
  • GO:1901224
  • GO:1903416
  • GO:2000510
C-type lectin domain family 2 member I
10090
  • T cell receptor signaling pathway
  • carbohydrate binding
  • cell surface
  • endoplasmic reticulum
  • external side of plasma membrane
  • membrane raft assembly
  • natural killer cell lectin-like receptor binding
  • negative regulation of osteoclast differentiation
  • positive regulation of immunological synapse formation
  • receptor clustering
  • regulation of T cell proliferation
  • regulation of actin filament polymerization
  • regulation of interleukin-2 production
  • transmembrane signaling receptor activity
  • GO:0001765
  • GO:0004888
  • GO:0005783
  • GO:0009897
  • GO:0009986
  • GO:0030246
  • GO:0030833
  • GO:0032663
  • GO:0042129
  • GO:0043113
  • GO:0045671
  • GO:0046703
  • GO:0050852
  • GO:2000522
Glycogen phosphorylase, liver form
10090
  • 5-phosphoribose 1-diphosphate biosynthetic process
  • AMP binding
  • ATP binding
  • SHG alpha-glucan phosphorylase activity
  • bile acid binding
  • carbohydrate binding
  • cytoplasm
  • cytosol
  • glucose binding
  • glucose homeostasis
  • glycogen catabolic process
  • glycogen metabolic process
  • glycogen phosphorylase activity
  • identical protein binding
  • linear malto-oligosaccharide phosphorylase activity
  • necroptotic process
  • purine nucleobase binding
  • pyridoxal phosphate binding
  • response to bacterium
  • vitamin binding
  • GO:0002060
  • GO:0005524
  • GO:0005536
  • GO:0005737
  • GO:0005829
  • GO:0005977
  • GO:0005980
  • GO:0006015
  • GO:0008184
  • GO:0009617
  • GO:0016208
  • GO:0019842
  • GO:0030170
  • GO:0030246
  • GO:0032052
  • GO:0042593
  • GO:0042802
  • GO:0070266
  • GO:0102250
  • GO:0102499
Cell migration-inducing and hyaluronan-binding protein
10090
  • ER retention sequence binding
  • carbohydrate binding
  • clathrin heavy chain binding
  • clathrin-coated endocytic vesicle
  • clathrin-coated pit
  • clathrin-coated vesicle membrane
  • cytoplasm
  • endoplasmic reticulum
  • extracellular region
  • fibrillar center
  • hyaluronan catabolic process
  • hyaluronan metabolic process
  • hyaluronic acid binding
  • hyalurononglucosaminidase activity
  • nuclear membrane
  • plasma membrane
  • positive regulation of cell migration
  • positive regulation of peptidyl-threonine phosphorylation
  • positive regulation of protein kinase C activity
  • positive regulation of protein targeting to membrane
  • positive regulation of release of sequestered calcium ion into cytosol
  • sensory perception of sound
  • GO:0001650
  • GO:0004415
  • GO:0005540
  • GO:0005576
  • GO:0005737
  • GO:0005783
  • GO:0005886
  • GO:0005905
  • GO:0007605
  • GO:0010800
  • GO:0030212
  • GO:0030214
  • GO:0030246
  • GO:0030335
  • GO:0030665
  • GO:0031965
  • GO:0032050
  • GO:0045334
  • GO:0046923
  • GO:0051281
  • GO:0090314
  • GO:1900020
Malectin
10090
  • carbohydrate binding
  • carbohydrate metabolic process
  • endoplasmic reticulum
  • endoplasmic reticulum membrane
  • enzyme binding
  • membrane
  • oligosaccharyltransferase complex
  • protein N-linked glycosylation
  • GO:0005783
  • GO:0005789
  • GO:0005975
  • GO:0006487
  • GO:0008250
  • GO:0016020
  • GO:0019899
  • GO:0030246
Brevican core protein
10090
  • GABA-ergic synapse
  • axon
  • axon initial segment
  • calcium ion binding
  • carbohydrate binding
  • cell surface
  • cell-matrix adhesion
  • central nervous system development
  • dendrite
  • extracellular matrix
  • extracellular space
  • glial cell differentiation
  • glutamatergic synapse
  • hippocampus development
  • hyaluronic acid binding
  • neuron projection extension
  • node of Ranvier
  • perineuronal net
  • perisynaptic extracellular matrix
  • positive regulation of neuroblast proliferation
  • skeletal system development
  • synapse
  • synapse maturation
  • synaptic membrane
  • GO:0001501
  • GO:0002052
  • GO:0005509
  • GO:0005540
  • GO:0005615
  • GO:0007160
  • GO:0007417
  • GO:0009986
  • GO:0010001
  • GO:0021766
  • GO:0030246
  • GO:0030424
  • GO:0030425
  • GO:0031012
  • GO:0033268
  • GO:0043194
  • GO:0045202
  • GO:0060074
  • GO:0072534
  • GO:0097060
  • GO:0098966
  • GO:0098978
  • GO:0098982
  • GO:1990138
Displaying entries 2391 - 2400 of 2433 in total

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01