GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID ▼	GO Labels	GO IDs
GL_000318	Chitinase-like protein 3	O35744	Mus musculus	10090	N-acetyl-beta-D-galactosaminidase activity beta-N-acetylhexosaminidase activity carbohydrate binding chitin binding chitin catabolic process cytoplasm cytoplasmic vesicle extracellular region extracellular space inflammatory response kinase binding nuclear envelope polysaccharide catabolic process positive regulation of chemokine production production of molecular mediator involved in inflammatory response rough endoplasmic reticulum lumen	GO:0000272 GO:0002532 GO:0004563 GO:0005576 GO:0005615 GO:0005635 GO:0005737 GO:0006032 GO:0006954 GO:0008061 GO:0019900 GO:0030246 GO:0031410 GO:0032722 GO:0048237 GO:0102148
GL_000520	Galectin-related protein	Q8VED9	Mus musculus	10090	carbohydrate binding collagen-containing extracellular matrix	GO:0030246 GO:0062023
GL_000808	Neurocan core protein	P55066	Mus musculus	10090	GABA-ergic synapse calcium ion binding carbohydrate binding cell adhesion central nervous system development extracellular space glial cell differentiation glutamatergic synapse hyaluronic acid binding modulation of chemical synaptic transmission perineuronal net perisynaptic extracellular matrix plasma membrane positive regulation of neuroblast proliferation regulation of postsynapse organization regulation of synapse structural plasticity skeletal system development synapse	GO:0001501 GO:0002052 GO:0005509 GO:0005540 GO:0005615 GO:0005886 GO:0007155 GO:0007417 GO:0010001 GO:0030246 GO:0045202 GO:0050804 GO:0051823 GO:0072534 GO:0098966 GO:0098978 GO:0098982 GO:0099175
GL_001383	CD209 antigen-like protein A	Q91ZX1	Mus musculus	10090	B cell adhesion calcium-dependent protein binding carbohydrate binding carbohydrate derivative binding cell surface endocytosis external side of plasma membrane immune response mannose binding membrane metal ion binding plasma membrane positive regulation of T cell proliferation positive regulation of viral life cycle regulation of T cell proliferation viral entry into host cell virus receptor activity	GO:0001618 GO:0005537 GO:0005886 GO:0006897 GO:0006955 GO:0009897 GO:0009986 GO:0016020 GO:0030246 GO:0042102 GO:0042129 GO:0046718 GO:0046872 GO:0048306 GO:0097323 GO:0097367 GO:1903902
GL_000271	Calreticulin	P14211	Mus musculus	10090	MHC class I peptide loading complex acrosomal vesicle calcium ion binding carbohydrate binding cardiac muscle cell differentiation cell surface cellular response to electrical stimulus cellular response to lithium ion cellular response to organic substance cellular response to virus cellular senescence collagen-containing extracellular matrix complement component C1q complex binding cortical actin cytoskeleton organization cortical granule cytolytic granule cytoplasm cytosol endoplasmic reticulum endoplasmic reticulum lumen endoplasmic reticulum membrane endoplasmic reticulum quality control compartment external side of plasma membrane extracellular region extracellular space hormone binding integrin binding iron ion binding mRNA binding membrane negative regulation of DNA-templated transcription negative regulation of intracellular steroid hormone receptor signaling pathway negative regulation of neuron differentiation negative regulation of retinoic acid receptor signaling pathway negative regulation of transcription by RNA polymerase II negative regulation of translation negative regulation of trophoblast cell migration nuclear androgen receptor binding nuclear envelope nuclear export signal receptor activity nucleus obsolete selective autophagy peptide antigen assembly with MHC class I protein complex peptide binding perinuclear region of cytoplasm phagocytic vesicle polysome positive regulation of cell cycle positive regulation of cell population proliferation positive regulation of dendritic cell chemotaxis positive regulation of endothelial cell migration positive regulation of gene expression positive regulation of non-canonical NF-kappaB signal transduction positive regulation of phagocytosis positive regulation of substrate adhesion-dependent cell spreading protein export from nucleus protein folding protein localization to nucleus protein stabilization protein-containing complex regulation of meiotic nuclear division response to estradiol response to glycoside response to testosterone response to xenobiotic stimulus sarcoplasmic reticulum sarcoplasmic reticulum lumen smooth endoplasmic reticulum spermatogenesis ubiquitin protein ligase binding ubiquitin-dependent ERAD pathway unfolded protein binding	GO:0000122 GO:0001669 GO:0001849 GO:0002502 GO:0003729 GO:0005049 GO:0005178 GO:0005506 GO:0005509 GO:0005576 GO:0005615 GO:0005634 GO:0005635 GO:0005737 GO:0005783 GO:0005788 GO:0005789 GO:0005790 GO:0005829 GO:0005844 GO:0006457 GO:0006611 GO:0007283 GO:0008284 GO:0009410 GO:0009897 GO:0009986 GO:0010595 GO:0010628 GO:0016020 GO:0016529 GO:0017148 GO:0030246 GO:0030433 GO:0030866 GO:0031625 GO:0032355 GO:0032991 GO:0033018 GO:0033144 GO:0033574 GO:0034504 GO:0040020 GO:0042277 GO:0042562 GO:0042824 GO:0044194 GO:0044322 GO:0045335 GO:0045665 GO:0045787 GO:0045892 GO:0048387 GO:0048471 GO:0050681 GO:0050766 GO:0050821 GO:0051082 GO:0055007 GO:0060473 GO:0061912 GO:0062023 GO:0071257 GO:0071285 GO:0071310 GO:0090398 GO:0098586 GO:1900026 GO:1901164 GO:1901224 GO:1903416 GO:2000510
GL_000165	C-type lectin domain family 2 member I	Q9WVF9	Mus musculus	10090	T cell receptor signaling pathway carbohydrate binding cell surface endoplasmic reticulum external side of plasma membrane membrane raft assembly natural killer cell lectin-like receptor binding negative regulation of osteoclast differentiation positive regulation of immunological synapse formation receptor clustering regulation of T cell proliferation regulation of actin filament polymerization regulation of interleukin-2 production transmembrane signaling receptor activity	GO:0001765 GO:0004888 GO:0005783 GO:0009897 GO:0009986 GO:0030246 GO:0030833 GO:0032663 GO:0042129 GO:0043113 GO:0045671 GO:0046703 GO:0050852 GO:2000522
GL_001641	Glycogen phosphorylase, liver form	Q9ET01	Mus musculus	10090	5-phosphoribose 1-diphosphate biosynthetic process AMP binding ATP binding SHG alpha-glucan phosphorylase activity bile acid binding carbohydrate binding cytoplasm cytosol glucose binding glucose homeostasis glycogen catabolic process glycogen metabolic process glycogen phosphorylase activity identical protein binding linear malto-oligosaccharide phosphorylase activity necroptotic process purine nucleobase binding pyridoxal phosphate binding response to bacterium vitamin binding	GO:0002060 GO:0005524 GO:0005536 GO:0005737 GO:0005829 GO:0005977 GO:0005980 GO:0006015 GO:0008184 GO:0009617 GO:0016208 GO:0019842 GO:0030170 GO:0030246 GO:0032052 GO:0042593 GO:0042802 GO:0070266 GO:0102250 GO:0102499
GL_000303	Cell migration-inducing and hyaluronan-binding protein	Q8BI06	Mus musculus	10090	ER retention sequence binding carbohydrate binding clathrin heavy chain binding clathrin-coated endocytic vesicle clathrin-coated pit clathrin-coated vesicle membrane cytoplasm endoplasmic reticulum extracellular region fibrillar center hyaluronan catabolic process hyaluronan metabolic process hyaluronic acid binding hyalurononglucosaminidase activity nuclear membrane plasma membrane positive regulation of cell migration positive regulation of peptidyl-threonine phosphorylation positive regulation of protein kinase C activity positive regulation of protein targeting to membrane positive regulation of release of sequestered calcium ion into cytosol sensory perception of sound	GO:0001650 GO:0004415 GO:0005540 GO:0005576 GO:0005737 GO:0005783 GO:0005886 GO:0005905 GO:0007605 GO:0010800 GO:0030212 GO:0030214 GO:0030246 GO:0030335 GO:0030665 GO:0031965 GO:0032050 GO:0045334 GO:0046923 GO:0051281 GO:0090314 GO:1900020
GL_001702	Malectin	Q6ZQI3	Mus musculus	10090	carbohydrate binding carbohydrate metabolic process endoplasmic reticulum endoplasmic reticulum membrane enzyme binding membrane oligosaccharyltransferase complex protein N-linked glycosylation	GO:0005783 GO:0005789 GO:0005975 GO:0006487 GO:0008250 GO:0016020 GO:0019899 GO:0030246
GL_000111	Brevican core protein	Q61361	Mus musculus	10090	GABA-ergic synapse axon axon initial segment calcium ion binding carbohydrate binding cell surface cell-matrix adhesion central nervous system development dendrite extracellular matrix extracellular space glial cell differentiation glutamatergic synapse hippocampus development hyaluronic acid binding neuron projection extension node of Ranvier perineuronal net perisynaptic extracellular matrix positive regulation of neuroblast proliferation skeletal system development synapse synapse maturation synaptic membrane	GO:0001501 GO:0002052 GO:0005509 GO:0005540 GO:0005615 GO:0007160 GO:0007417 GO:0009986 GO:0010001 GO:0021766 GO:0030246 GO:0030424 GO:0030425 GO:0031012 GO:0033268 GO:0043194 GO:0045202 GO:0060074 GO:0072534 GO:0097060 GO:0098966 GO:0098978 GO:0098982 GO:1990138