GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID	GO Labels	GO IDs
GL_002003	E-selectin	P98107	Bos taurus	9913	actin filament-based process calcium ion binding caveola clathrin-coated pit cortical cytoskeleton external side of plasma membrane extracellular space heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules leukocyte tethering or rolling oligosaccharide binding perinuclear region of cytoplasm phospholipase binding positive regulation of leukocyte migration positive regulation of leukocyte tethering or rolling positive regulation of receptor internalization response to cytokine response to interleukin-1 sialic acid binding transmembrane signaling receptor activity	GO:0002092 GO:0002687 GO:0004888 GO:0005509 GO:0005615 GO:0005901 GO:0005905 GO:0007157 GO:0009897 GO:0030029 GO:0030863 GO:0033691 GO:0034097 GO:0043274 GO:0048471 GO:0050901 GO:0070492 GO:0070555 GO:1903238
GL_002242	Agglutinin	Q7Y041	Hippeastrum vittatum	231486	response to other organism	GO:0051707
GL_001022	Pulmonary surfactant-associated protein D	P35247	Homo sapiens	9606	carbohydrate binding clathrin-coated endocytic vesicle collagen trimer defense response to bacterium endocytic vesicle endoplasmic reticulum membrane extracellular region extracellular space identical protein binding innate immune response lung alveolus development lysosome macrophage chemotaxis multivesicular body negative regulation of T cell proliferation negative regulation of interleukin-2 production positive regulation of phagocytosis reactive oxygen species metabolic process receptor-mediated endocytosis regulation of cytokine production respiratory gaseous exchange by respiratory system surfactant homeostasis	GO:0001817 GO:0005576 GO:0005581 GO:0005615 GO:0005764 GO:0005771 GO:0005789 GO:0006898 GO:0007585 GO:0030139 GO:0030246 GO:0032703 GO:0042130 GO:0042742 GO:0042802 GO:0043129 GO:0045087 GO:0045334 GO:0048246 GO:0048286 GO:0050766 GO:0072593
GL_001880	Uncharacterized isomerase YNR071C	P53757	Saccharomyces cerevisiae S288C	559292	aldose 1-epimerase activity carbohydrate binding galactose catabolic process via UDP-galactose glucose metabolic process	GO:0004034 GO:0006006 GO:0030246 GO:0033499
GL_002054	Protein ERGIC-53	Q62902	Rattus norvegicus	10116	COPII-coated ER to Golgi transport vesicle Golgi apparatus Golgi membrane Golgi organization calcium ion binding endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum organization endoplasmic reticulum to Golgi vesicle-mediated transport endoplasmic reticulum-Golgi intermediate compartment endoplasmic reticulum-Golgi intermediate compartment membrane identical protein binding mannose binding metal ion binding positive regulation of organelle organization protein transport sarcomere	GO:0000139 GO:0005509 GO:0005537 GO:0005783 GO:0005789 GO:0005793 GO:0005794 GO:0006888 GO:0007029 GO:0007030 GO:0010638 GO:0015031 GO:0030017 GO:0030134 GO:0033116 GO:0042802 GO:0046872
GL_001319	Beta-galactosidase	B7UJI9	Escherichia coli O127:H6 str. E2348/69	574521	beta-galactosidase activity beta-galactosidase complex carbohydrate binding carbohydrate metabolic process magnesium ion binding organic substance catabolic process	GO:0000287 GO:0004565 GO:0005975 GO:0009341 GO:0030246 GO:1901575
GL_001094	Seed lectin	P81371	Vatairea macrocarpa	77050	carbohydrate binding metal ion binding	GO:0030246 GO:0046872
GL_001539	Glucans biosynthesis protein D	Q4KHN0	Pseudomonas protegens Pf-5	220664	carbohydrate binding catalytic activity glucan biosynthetic process periplasmic space	GO:0003824 GO:0009250 GO:0030246 GO:0042597
GL_000557	Intelectin-1a	O88310	Mus musculus	10090	brush border membrane calcium ion binding carbohydrate binding collagen-containing extracellular matrix extracellular space identical protein binding membrane raft oligosaccharide binding positive regulation of glucose import positive regulation of protein phosphorylation protein homotrimerization receptor complex response to nematode side of membrane	GO:0001934 GO:0005509 GO:0005615 GO:0009624 GO:0030246 GO:0031526 GO:0042802 GO:0043235 GO:0045121 GO:0046326 GO:0062023 GO:0070207 GO:0070492 GO:0098552
GL_001483	F-box protein PP2-A14	Q9FJ80	Arabidopsis thaliana	3702	carbohydrate binding nucleus protein ubiquitination	GO:0005634 GO:0016567 GO:0030246