GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID ▼	GO Labels	GO IDs
GL_000140	C-type lectin domain family 11 member A	Q9Y240	Homo sapiens	9606	carbohydrate binding cytoplasm extracellular region extracellular space growth factor activity ossification positive regulation of cell population proliferation	GO:0001503 GO:0005576 GO:0005615 GO:0005737 GO:0008083 GO:0008284 GO:0030246
GL_001840	Sucrase-isomaltase, intestinal	P14410	Homo sapiens	9606	Golgi apparatus alpha-1,4-glucosidase activity apical plasma membrane brush border carbohydrate binding extracellular exosome oligo-1,6-glucosidase activity plasma membrane polysaccharide digestion sucrose alpha-glucosidase activity sucrose catabolic process	GO:0004558 GO:0004574 GO:0004575 GO:0005794 GO:0005886 GO:0005903 GO:0005987 GO:0016324 GO:0030246 GO:0044245 GO:0070062
GL_000317	Chitinase-3-like protein 2	Q15782	Homo sapiens	9606	carbohydrate binding carbohydrate metabolic process chitin binding chitin catabolic process extracellular region extracellular space hydrolase activity	GO:0005576 GO:0005615 GO:0005975 GO:0006032 GO:0008061 GO:0016787 GO:0030246
GL_002404	Collectin-11	Q9BWP8	Homo sapiens	9606	DNA binding antimicrobial humoral response calcium ion binding calcium-dependent carbohydrate binding cell surface pattern recognition receptor signaling pathway collagen trimer complement activation complement activation, lectin pathway developmental process execution phase of apoptosis external side of plasma membrane extracellular region extracellular space fucose binding identical protein binding mannose binding oligosaccharide binding positive regulation of opsonization proteolysis serine-type endopeptidase complex	GO:0001867 GO:0002752 GO:0003677 GO:0005509 GO:0005537 GO:0005576 GO:0005581 GO:0005615 GO:0006508 GO:0006956 GO:0009897 GO:0019730 GO:0032502 GO:0042802 GO:0042806 GO:0070492 GO:0097194 GO:0120153 GO:1903028 GO:1905370
GL_000150	C-type lectin domain family 19 member A	Q6UXS0	Homo sapiens	9606	carbohydrate binding extracellular region	GO:0005576 GO:0030246
GL_002411	Paired immunoglobulin-like type 2 receptor alpha	Q9UKJ1	Homo sapiens	9606	MHC class I protein binding extracellular exosome plasma membrane signal transduction	GO:0005886 GO:0007165 GO:0042288 GO:0070062
GL_000627	Killer cell lectin-like receptor subfamily F member 2	D3W0D1	Homo sapiens	9606	carbohydrate binding natural killer cell degranulation plasma membrane positive regulation of cytokine production protein homodimerization activity	GO:0001819 GO:0005886 GO:0030246 GO:0042803 GO:0043320
GL_000195	C-type lectin domain family 6 member A	Q6EIG7	Homo sapiens	9606	adaptive immune response antifungal innate immune response calcium ion binding carbohydrate binding defense response to fungus detection of yeast external side of plasma membrane innate immune response mannose binding pattern recognition receptor activity phospholipase binding plasma membrane positive regulation of T-helper 17 type immune response positive regulation of canonical NF-kappaB signal transduction positive regulation of cytokine production positive regulation of intracellular signal transduction positive regulation of peptidyl-tyrosine phosphorylation response to yeast stimulatory C-type lectin receptor signaling pathway	GO:0001819 GO:0001878 GO:0001879 GO:0002223 GO:0002250 GO:0005509 GO:0005537 GO:0005886 GO:0009897 GO:0030246 GO:0038187 GO:0043123 GO:0043274 GO:0045087 GO:0050731 GO:0050832 GO:0061760 GO:1902533 GO:2000318
GL_002047	P-selectin	P16109	Homo sapiens	9606	calcium ion binding calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules calcium-dependent protein binding calcium-mediated signaling using intracellular calcium source cell adhesion defense response to Gram-negative bacterium external side of plasma membrane extracellular space fucose binding glycosphingolipid binding heparin binding heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules inflammatory response leukocyte cell-cell adhesion leukocyte tethering or rolling lipopolysaccharide binding oligosaccharide binding plasma membrane platelet alpha granule membrane platelet dense granule membrane positive regulation of leukocyte migration positive regulation of leukocyte tethering or rolling positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of platelet activation regulation of integrin activation response to cytokine response to lipopolysaccharide sialic acid binding	GO:0001530 GO:0002687 GO:0005509 GO:0005615 GO:0005886 GO:0006954 GO:0007155 GO:0007157 GO:0007159 GO:0008201 GO:0009897 GO:0010572 GO:0016339 GO:0031088 GO:0031092 GO:0032496 GO:0033623 GO:0033691 GO:0034097 GO:0035584 GO:0042806 GO:0043208 GO:0048306 GO:0050829 GO:0050901 GO:0051897 GO:0070492 GO:1903238
GL_000555	Integral membrane protein DGCR2/IDD	P98153	Homo sapiens	9606	animal organ morphogenesis carbohydrate binding cell adhesion cognition membrane	GO:0007155 GO:0009887 GO:0016020 GO:0030246 GO:0050890