GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database Last Updated
MCAW-DB July 10, 2019
UniLectin June 14, 2023
UniProt February 16, 2024
Lectin Frontier DataBase (LfDB) February 16, 2024
CarboGrove June 14, 2023
GlyCosmos Lectin Lectin Name UniProt ID Monosaccharide Specificities Species Taxonomy ID GO Labels ▲ GO IDs
Polycystin-1-like protein 2
10090
  • G-protein alpha-subunit binding
  • calcium channel activity
  • calcium ion binding
  • carbohydrate binding
  • detection of mechanical stimulus
  • membrane
  • GO:0001965
  • GO:0005262
  • GO:0005509
  • GO:0016020
  • GO:0030246
  • GO:0050982
Brevican core protein
10090
  • GABA-ergic synapse
  • axon
  • axon initial segment
  • calcium ion binding
  • carbohydrate binding
  • cell surface
  • cell-matrix adhesion
  • central nervous system development
  • dendrite
  • extracellular matrix
  • extracellular space
  • glial cell differentiation
  • glutamatergic synapse
  • hippocampus development
  • hyaluronic acid binding
  • neuron projection extension
  • node of Ranvier
  • perineuronal net
  • perisynaptic extracellular matrix
  • positive regulation of neuroblast proliferation
  • skeletal system development
  • synapse
  • synapse maturation
  • synaptic membrane
  • GO:0001501
  • GO:0002052
  • GO:0005509
  • GO:0005540
  • GO:0005615
  • GO:0007160
  • GO:0007417
  • GO:0009986
  • GO:0010001
  • GO:0021766
  • GO:0030246
  • GO:0030424
  • GO:0030425
  • GO:0031012
  • GO:0033268
  • GO:0043194
  • GO:0045202
  • GO:0060074
  • GO:0072534
  • GO:0097060
  • GO:0098966
  • GO:0098978
  • GO:0098982
  • GO:1990138
Brevican core protein
10116
  • GABA-ergic synapse
  • axon
  • axon initial segment
  • carbohydrate binding
  • cell surface
  • cell-matrix adhesion
  • central nervous system development
  • dendrite
  • extracellular matrix
  • extracellular space
  • glial cell differentiation
  • gliogenesis
  • glutamatergic synapse
  • hippocampus development
  • hyaluronic acid binding
  • neuron projection extension
  • node of Ranvier
  • perineuronal net
  • perisynaptic extracellular matrix
  • positive regulation of neuroblast proliferation
  • regulation of neuronal synaptic plasticity
  • side of membrane
  • skeletal system development
  • synapse
  • synapse maturation
  • synaptic membrane
  • GO:0001501
  • GO:0002052
  • GO:0005540
  • GO:0005615
  • GO:0007160
  • GO:0007417
  • GO:0009986
  • GO:0010001
  • GO:0021766
  • GO:0030246
  • GO:0030424
  • GO:0030425
  • GO:0031012
  • GO:0033268
  • GO:0042063
  • GO:0043194
  • GO:0045202
  • GO:0048168
  • GO:0060074
  • GO:0072534
  • GO:0097060
  • GO:0098552
  • GO:0098966
  • GO:0098978
  • GO:0098982
  • GO:1990138
Aggrecan core protein
10116
  • GABA-ergic synapse
  • basement membrane
  • calcium ion binding
  • carbohydrate binding
  • cartilage condensation
  • cell adhesion
  • cellular response to growth factor stimulus
  • central nervous system development
  • chondroblast differentiation
  • chondrocyte development
  • collagen fibril organization
  • extracellular matrix
  • extracellular space
  • glial cell differentiation
  • glutamatergic synapse
  • heart development
  • hyaluronic acid binding
  • negative regulation of cell migration
  • neuronal cell body
  • ossification
  • perineuronal net
  • perisynaptic extracellular matrix
  • positive regulation of neuroblast proliferation
  • proteoglycan biosynthetic process
  • response to acidic pH
  • response to glucose
  • response to gravity
  • response to mechanical stimulus
  • response to organic cyclic compound
  • response to xenobiotic stimulus
  • skeletal system development
  • spinal cord development
  • synapse
  • GO:0001501
  • GO:0001502
  • GO:0001503
  • GO:0002052
  • GO:0002063
  • GO:0005509
  • GO:0005540
  • GO:0005604
  • GO:0005615
  • GO:0007155
  • GO:0007417
  • GO:0007507
  • GO:0009410
  • GO:0009612
  • GO:0009629
  • GO:0009749
  • GO:0010001
  • GO:0010447
  • GO:0014070
  • GO:0021510
  • GO:0030166
  • GO:0030199
  • GO:0030246
  • GO:0030336
  • GO:0031012
  • GO:0043025
  • GO:0045202
  • GO:0060591
  • GO:0071363
  • GO:0072534
  • GO:0098966
  • GO:0098978
  • GO:0098982
Aggrecan core protein
10090
  • GABA-ergic synapse
  • basement membrane
  • calcium ion binding
  • carbohydrate binding
  • cartilage condensation
  • cell adhesion
  • central nervous system development
  • chondrocyte development
  • collagen fibril organization
  • extracellular matrix
  • extracellular space
  • glial cell differentiation
  • glutamatergic synapse
  • heart development
  • hyaluronic acid binding
  • negative regulation of cell migration
  • neuronal cell body
  • perineuronal net
  • perisynaptic extracellular matrix
  • positive regulation of neuroblast proliferation
  • proteoglycan biosynthetic process
  • skeletal system development
  • synapse
  • GO:0001501
  • GO:0001502
  • GO:0002052
  • GO:0002063
  • GO:0005509
  • GO:0005540
  • GO:0005604
  • GO:0005615
  • GO:0007155
  • GO:0007417
  • GO:0007507
  • GO:0010001
  • GO:0030166
  • GO:0030199
  • GO:0030246
  • GO:0030336
  • GO:0031012
  • GO:0043025
  • GO:0045202
  • GO:0072534
  • GO:0098966
  • GO:0098978
  • GO:0098982
Neurocan core protein
10116
  • GABA-ergic synapse
  • calcium ion binding
  • carbohydrate binding
  • cell adhesion
  • central nervous system development
  • extracellular space
  • glial cell differentiation
  • glutamatergic synapse
  • hyaluronic acid binding
  • modulation of chemical synaptic transmission
  • perineuronal net
  • perisynaptic extracellular matrix
  • plasma membrane
  • positive regulation of neuroblast proliferation
  • regulation of postsynapse organization
  • regulation of synapse structural plasticity
  • skeletal system development
  • synapse
  • GO:0001501
  • GO:0002052
  • GO:0005509
  • GO:0005540
  • GO:0005615
  • GO:0005886
  • GO:0007155
  • GO:0007417
  • GO:0010001
  • GO:0030246
  • GO:0045202
  • GO:0050804
  • GO:0051823
  • GO:0072534
  • GO:0098966
  • GO:0098978
  • GO:0098982
  • GO:0099175
Neurocan core protein
10090
  • GABA-ergic synapse
  • calcium ion binding
  • carbohydrate binding
  • cell adhesion
  • central nervous system development
  • extracellular space
  • glial cell differentiation
  • glutamatergic synapse
  • hyaluronic acid binding
  • modulation of chemical synaptic transmission
  • perineuronal net
  • perisynaptic extracellular matrix
  • plasma membrane
  • positive regulation of neuroblast proliferation
  • regulation of postsynapse organization
  • regulation of synapse structural plasticity
  • skeletal system development
  • synapse
  • GO:0001501
  • GO:0002052
  • GO:0005509
  • GO:0005540
  • GO:0005615
  • GO:0005886
  • GO:0007155
  • GO:0007417
  • GO:0010001
  • GO:0030246
  • GO:0045202
  • GO:0050804
  • GO:0051823
  • GO:0072534
  • GO:0098966
  • GO:0098978
  • GO:0098982
  • GO:0099175
Immune-associated nucleotide-binding protein 10
3702
  • GTP binding
  • carbohydrate binding
  • GO:0005525
  • GO:0030246
Glucosidase 2 subunit alpha
284812
  • Glc2Man9GlcNAc2 oligosaccharide glucosidase activity
  • N-glycan processing
  • alpha-glucosidase activity
  • carbohydrate binding
  • carbohydrate metabolic process
  • endoplasmic reticulum
  • glucosidase II complex
  • protein N-linked glycosylation
  • GO:0005783
  • GO:0005975
  • GO:0006487
  • GO:0006491
  • GO:0017177
  • GO:0030246
  • GO:0090599
  • GO:0106407
Alpha-mannosidase 2
3702
  • Golgi apparatus
  • Golgi cis cisterna
  • Golgi membrane
  • alpha-mannosidase activity
  • carbohydrate binding
  • endosome
  • hyperosmotic salinity response
  • mannose metabolic process
  • mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity
  • metal ion binding
  • protein N-linked glycosylation
  • trans-Golgi network
  • GO:0000137
  • GO:0000139
  • GO:0004559
  • GO:0004572
  • GO:0005768
  • GO:0005794
  • GO:0005802
  • GO:0006013
  • GO:0006487
  • GO:0030246
  • GO:0042538
  • GO:0046872
Displaying entries 271 - 280 of 2433 in total

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01