GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Monosaccharide Specificities	Species	Taxonomy ID	GO Labels ▲	GO IDs
GL_001261	ATP-dependent 6-phosphofructokinase, muscle type	P47858		Rattus norvegicus	10116	6-phosphofructokinase activity 6-phosphofructokinase complex AMP binding ATP binding apical plasma membrane canonical glycolysis carbohydrate binding cytosol fructose 1,6-bisphosphate metabolic process fructose 6-phosphate metabolic process fructose binding fructose-6-phosphate binding glucose homeostasis glycogen catabolic process glycolysis from storage polysaccharide through glucose-1-phosphate glycolytic process glycolytic process through fructose-6-phosphate identical protein binding intracellular glucose homeostasis kinase binding membrane metal ion binding monosaccharide binding muscle cell cellular homeostasis nucleus phosphofructokinase activity positive regulation of insulin secretion positive regulation of transcription by RNA polymerase II sperm principal piece	GO:0001678 GO:0003872 GO:0005524 GO:0005634 GO:0005829 GO:0005945 GO:0005980 GO:0006002 GO:0006096 GO:0008443 GO:0016020 GO:0016208 GO:0016324 GO:0019900 GO:0030246 GO:0030388 GO:0032024 GO:0042593 GO:0042802 GO:0045944 GO:0046716 GO:0046872 GO:0048029 GO:0061615 GO:0061621 GO:0070061 GO:0070095 GO:0093001 GO:0097228
GL_001262	ATP-dependent 6-phosphofructokinase, muscle type	P47857		Mus musculus	10090	6-phosphofructokinase activity 6-phosphofructokinase complex AMP binding ATP binding apical plasma membrane canonical glycolysis carbohydrate binding cytosol fructose 1,6-bisphosphate metabolic process fructose 6-phosphate metabolic process fructose binding fructose-6-phosphate binding glucose homeostasis glycogen catabolic process glycolysis from storage polysaccharide through glucose-1-phosphate glycolytic process glycolytic process through fructose-6-phosphate identical protein binding kinase binding membrane metal ion binding monosaccharide binding muscle cell cellular homeostasis nucleus phosphofructokinase activity positive regulation of insulin secretion positive regulation of transcription by RNA polymerase II sperm principal piece	GO:0003872 GO:0005524 GO:0005634 GO:0005829 GO:0005945 GO:0005980 GO:0006002 GO:0006096 GO:0008443 GO:0016020 GO:0016208 GO:0016324 GO:0019900 GO:0030246 GO:0030388 GO:0032024 GO:0042593 GO:0042802 GO:0045944 GO:0046716 GO:0046872 GO:0048029 GO:0061615 GO:0061621 GO:0070061 GO:0070095 GO:0093001 GO:0097228
GL_001505	GDH/6PGL endoplasmic bifunctional protein	Q8CFX1		Mus musculus	10090	6-phosphogluconolactonase activity NADP binding NADP metabolic process carbohydrate binding endoplasmic reticulum endoplasmic reticulum lumen glucose 1-dehydrogenase (NAD+) activity glucose 1-dehydrogenase (NADP+) activity glucose 1-dehydrogenase [NAD(P)] activity glucose metabolic process glucose-6-phosphate dehydrogenase activity pentose-phosphate shunt pentose-phosphate shunt, oxidative branch regulation of cortisol biosynthetic process sarcoplasmic reticulum	GO:0004345 GO:0005783 GO:0005788 GO:0006006 GO:0006098 GO:0006739 GO:0009051 GO:0016529 GO:0017057 GO:0030246 GO:0047934 GO:0047935 GO:0047936 GO:0050661 GO:2000064
GL_001504	GDH/6PGL endoplasmic bifunctional protein	O95479		Homo sapiens	9606	6-phosphogluconolactonase activity NADP binding carbohydrate binding endoplasmic reticulum endoplasmic reticulum lumen glucose 1-dehydrogenase (NAD+) activity glucose 1-dehydrogenase (NADP+) activity glucose 1-dehydrogenase [NAD(P)] activity glucose metabolic process glucose-6-phosphate dehydrogenase activity pentose-phosphate shunt, oxidative branch regulation of cortisol biosynthetic process response to alcohol response to nutrient levels	GO:0004345 GO:0005783 GO:0005788 GO:0006006 GO:0009051 GO:0017057 GO:0030246 GO:0031667 GO:0047934 GO:0047935 GO:0047936 GO:0050661 GO:0097305 GO:2000064
GL_001844	Sulfoquinovosidase	P32138		Escherichia coli K-12	83333	6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde carbohydrate binding carbohydrate metabolic process hydrolase activity, hydrolyzing O-glycosyl compounds sulfoquinovosidase activity	GO:0004553 GO:0005975 GO:0030246 GO:0061720 GO:1990929
GL_001884	Uncharacterized protein YihR	P32139		Escherichia coli K-12	83333	6-sulfoquinovose(1-) catabolic process aldose 1-epimerase activity carbohydrate binding galactose catabolic process via UDP-galactose glucose metabolic process single-species biofilm formation	GO:0004034 GO:0006006 GO:0030246 GO:0033499 GO:0044010 GO:1902777
GL_001675	L-arabinose-binding periplasmic protein	P02924		Escherichia coli K-12	83333	ABC-type monosaccharide transporter activity ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing L-arabinose transmembrane transport carbohydrate binding membrane monosaccharide binding outer membrane-bounded periplasmic space	GO:0015407 GO:0016020 GO:0030246 GO:0030288 GO:0042882 GO:0048029 GO:0055052
GL_001644	Glycogen phosphorylase, muscle form	Q9WUB3		Mus musculus	10090	AMP binding SHG alpha-glucan phosphorylase activity Z disc carbohydrate binding cytoplasm glycogen catabolic process glycogen metabolic process glycogen phosphorylase activity intracellular calcium ion homeostasis linear malto-oligosaccharide phosphorylase activity organic cyclic compound binding pyridoxal phosphate binding response to cAMP response to hypoxia response to organic substance sarcoplasmic reticulum	GO:0001666 GO:0005737 GO:0005977 GO:0005980 GO:0006874 GO:0008184 GO:0010033 GO:0016208 GO:0016529 GO:0030018 GO:0030170 GO:0030246 GO:0051591 GO:0097159 GO:0102250 GO:0102499
GL_001643	Glycogen phosphorylase, muscle form	P09812		Rattus norvegicus	10116	AMP binding SHG alpha-glucan phosphorylase activity carbohydrate binding cytoplasm glycogen catabolic process glycogen metabolic process glycogen phosphorylase activity intracellular calcium ion homeostasis linear malto-oligosaccharide phosphorylase activity organic cyclic compound binding pyridoxal phosphate binding response to cAMP response to hypoxia response to organic substance sarcoplasmic reticulum	GO:0001666 GO:0005737 GO:0005977 GO:0005980 GO:0006874 GO:0008184 GO:0010033 GO:0016208 GO:0016529 GO:0030170 GO:0030246 GO:0051591 GO:0097159 GO:0102250 GO:0102499
GL_001077	Ricin	P02879	Gal	Ricinus communis	3988	AMP binding carbohydrate binding defense response killing of cells of another organism negative regulation of translation rRNA N-glycosylase activity toxin activity	GO:0006952 GO:0016208 GO:0017148 GO:0030246 GO:0030598 GO:0031640 GO:0090729