GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database Last Updated
MCAW-DB July 10, 2019
UniLectin June 14, 2023
UniProt February 16, 2024
Lectin Frontier DataBase (LfDB) February 16, 2024
CarboGrove June 14, 2023
GlyCosmos Lectin Lectin Name UniProt ID Monosaccharide Specificities Species Taxonomy ID ▼ GO Labels GO IDs
Cation-dependent mannose-6-phosphate receptor
9913
  • Golgi apparatus
  • endosome
  • lysosomal membrane
  • lysosomal transport
  • protein domain specific binding
  • protein targeting to lysosome
  • trans-Golgi network
  • GO:0005765
  • GO:0005768
  • GO:0005794
  • GO:0005802
  • GO:0006622
  • GO:0007041
  • GO:0019904
Secretory phospholipase A2 receptor
9913
  • carbohydrate binding
  • cell surface
  • extracellular region
  • oxidative stress-induced premature senescence
  • phospholipase binding
  • plasma membrane
  • positive regulation of DNA damage response, signal transduction by p53 class mediator
  • positive regulation of arachidonic acid secretion
  • positive regulation of cytokine production
  • positive regulation of podocyte apoptotic process
  • reactive oxygen species metabolic process
  • receptor complex
  • receptor-mediated endocytosis
  • replicative senescence
  • signaling receptor activity
  • GO:0001819
  • GO:0005576
  • GO:0005886
  • GO:0006898
  • GO:0009986
  • GO:0030246
  • GO:0038023
  • GO:0043235
  • GO:0043274
  • GO:0043517
  • GO:0072593
  • GO:0090238
  • GO:0090399
  • GO:0090403
  • GO:1904635
P-selectin
9913
  • calcium ion binding
  • calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
  • external side of plasma membrane
  • extracellular space
  • heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
  • leukocyte tethering or rolling
  • oligosaccharide binding
  • plasma membrane
  • positive regulation of leukocyte tethering or rolling
  • response to cytokine
  • sialic acid binding
  • GO:0005509
  • GO:0005615
  • GO:0005886
  • GO:0007157
  • GO:0009897
  • GO:0016339
  • GO:0033691
  • GO:0034097
  • GO:0050901
  • GO:0070492
  • GO:1903238
C-type lectin domain family 4 member E
9913
  • Fc-gamma receptor signaling pathway
  • T cell differentiation involved in immune response
  • antifungal innate immune response
  • calcium ion binding
  • carbohydrate binding
  • defense response to bacterium
  • external side of plasma membrane
  • glycolipid binding
  • pattern recognition receptor activity
  • pattern recognition receptor signaling pathway
  • phagocytic vesicle membrane
  • positive regulation of cytokine production
  • GO:0001819
  • GO:0002221
  • GO:0002292
  • GO:0005509
  • GO:0009897
  • GO:0030246
  • GO:0030670
  • GO:0038094
  • GO:0038187
  • GO:0042742
  • GO:0051861
  • GO:0061760
Adhesion G protein-coupled receptor L2
9913
  • G protein-coupled receptor activity
  • carbohydrate binding
  • cell surface receptor signaling pathway
  • extracellular space
  • membrane
  • signal transduction
  • GO:0004930
  • GO:0005615
  • GO:0007165
  • GO:0007166
  • GO:0016020
  • GO:0030246
F-box only protein 2
9913
  • SCF ubiquitin ligase complex
  • SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
  • carbohydrate binding
  • cytoplasm
  • cytosol
  • endoplasmic reticulum
  • glycoprotein catabolic process
  • membrane
  • protein ubiquitination
  • ubiquitin-dependent ERAD pathway
  • GO:0005737
  • GO:0005783
  • GO:0005829
  • GO:0006516
  • GO:0016020
  • GO:0016567
  • GO:0019005
  • GO:0030246
  • GO:0030433
  • GO:0031146
Pulmonary surfactant-associated protein A
9913
  • carbohydrate binding
  • collagen trimer
  • extracellular space
  • metal ion binding
  • multivesicular body
  • respiratory gaseous exchange by respiratory system
  • GO:0005581
  • GO:0005615
  • GO:0005771
  • GO:0007585
  • GO:0030246
  • GO:0046872
Lithostathine
9913
  • antimicrobial humoral immune response mediated by antimicrobial peptide
  • extracellular space
  • oligosaccharide binding
  • peptidoglycan binding
  • positive regulation of cell population proliferation
  • response to peptide hormone
  • signaling receptor activity
  • GO:0005615
  • GO:0008284
  • GO:0038023
  • GO:0042834
  • GO:0043434
  • GO:0061844
  • GO:0070492
Serum amyloid P-component
9913
  • calcium ion binding
  • carbohydrate binding
  • complement component C1q complex binding
  • extracellular space
  • identical protein binding
  • innate immune response
  • negative regulation by host of viral exo-alpha-sialidase activity
  • negative regulation by host of viral glycoprotein metabolic process
  • negative regulation of monocyte differentiation
  • negative regulation of viral entry into host cell
  • virion binding
  • GO:0001849
  • GO:0005509
  • GO:0005615
  • GO:0030246
  • GO:0042802
  • GO:0044869
  • GO:0044871
  • GO:0045087
  • GO:0045656
  • GO:0046597
  • GO:0046790
F-box only protein 6
9913
  • DNA repair
  • SCF ubiquitin ligase complex
  • SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
  • carbohydrate binding
  • cytoplasm
  • endoplasmic reticulum quality control compartment
  • glycoprotein catabolic process
  • protein ubiquitination
  • response to unfolded protein
  • ubiquitin protein ligase activity
  • ubiquitin-dependent ERAD pathway
  • GO:0005737
  • GO:0006281
  • GO:0006516
  • GO:0006986
  • GO:0016567
  • GO:0019005
  • GO:0030246
  • GO:0030433
  • GO:0031146
  • GO:0044322
  • GO:0061630
Displaying entries 31 - 40 of 2433 in total

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01