GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database Last Updated
MCAW-DB July 10, 2019
UniLectin June 14, 2023
UniProt February 16, 2024
Lectin Frontier DataBase (LfDB) February 16, 2024
CarboGrove June 14, 2023
GlyCosmos Lectin Lectin Name UniProt ID Monosaccharide Specificities ▼ Species Taxonomy ID GO Labels GO IDs
Beta-galactoside-binding lectin
  • Gal
9031
  • carbohydrate binding
  • extracellular space
  • laminin binding
  • GO:0005615
  • GO:0030246
  • GO:0043236
Galactose-binding lectin
  • Gal
3818
  • carbohydrate binding
  • metal ion binding
  • GO:0030246
  • GO:0046872
Galectin-3
  • Gal
9606
  • IgE binding
  • RNA binding
  • RNA splicing
  • carbohydrate binding
  • cell surface
  • chemoattractant activity
  • collagen-containing extracellular matrix
  • cytoplasm
  • cytosol
  • eosinophil chemotaxis
  • epithelial cell differentiation
  • extracellular exosome
  • extracellular region
  • extracellular space
  • ficolin-1-rich granule membrane
  • immunological synapse
  • innate immune response
  • laminin binding
  • mRNA processing
  • macrophage chemotaxis
  • membrane
  • mitochondrial inner membrane
  • molecular condensate scaffold activity
  • monocyte chemotaxis
  • mononuclear cell migration
  • negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
  • negative regulation of T cell receptor signaling pathway
  • negative regulation of endocytosis
  • negative regulation of extrinsic apoptotic signaling pathway
  • negative regulation of immunological synapse formation
  • negative regulation of protein tyrosine phosphatase activity
  • neutrophil chemotaxis
  • nucleoplasm
  • nucleus
  • plasma membrane
  • positive chemotaxis
  • positive regulation of calcium ion import
  • positive regulation of mononuclear cell migration
  • positive regulation of protein localization to plasma membrane
  • positive regulation of protein-containing complex assembly
  • protein phosphatase binding
  • protein phosphatase inhibitor activity
  • regulation of T cell apoptotic process
  • regulation of T cell proliferation
  • regulation of extrinsic apoptotic signaling pathway via death domain receptors
  • secretory granule membrane
  • spliceosomal complex
  • GO:0001772
  • GO:0002548
  • GO:0003723
  • GO:0004864
  • GO:0005576
  • GO:0005615
  • GO:0005634
  • GO:0005654
  • GO:0005681
  • GO:0005737
  • GO:0005743
  • GO:0005829
  • GO:0005886
  • GO:0006397
  • GO:0008380
  • GO:0009986
  • GO:0016020
  • GO:0019863
  • GO:0019903
  • GO:0030246
  • GO:0030593
  • GO:0030667
  • GO:0030855
  • GO:0031334
  • GO:0042056
  • GO:0042129
  • GO:0043236
  • GO:0045087
  • GO:0045806
  • GO:0048245
  • GO:0048246
  • GO:0050860
  • GO:0050918
  • GO:0062023
  • GO:0070062
  • GO:0070232
  • GO:0071674
  • GO:0071677
  • GO:0090280
  • GO:0101003
  • GO:0140693
  • GO:1902041
  • GO:1903078
  • GO:1903614
  • GO:2000521
  • GO:2001189
  • GO:2001237
Galectin-7
  • Gal
9606
  • apoptotic process
  • carbohydrate binding
  • cytoplasm
  • extracellular exosome
  • extracellular space
  • heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
  • nucleus
  • GO:0005615
  • GO:0005634
  • GO:0005737
  • GO:0006915
  • GO:0007157
  • GO:0030246
  • GO:0070062
Lectin
  • Gal
3806
  • carbohydrate binding
  • defense response
  • metal ion binding
  • regulation of defense response to virus
  • GO:0006952
  • GO:0030246
  • GO:0046872
  • GO:0050688
Agglutinin alpha chain
  • Gal
3496
  • carbohydrate binding
  • GO:0030246
Galectin
  • Gal
64608
  • carbohydrate binding
  • GO:0030246
Ricin
  • Gal
3988
  • AMP binding
  • carbohydrate binding
  • defense response
  • killing of cells of another organism
  • negative regulation of translation
  • rRNA N-glycosylase activity
  • toxin activity
  • GO:0006952
  • GO:0016208
  • GO:0017148
  • GO:0030246
  • GO:0030598
  • GO:0031640
  • GO:0090729
Agglutinin alpha chain
  • Gal
3490
  • IgA binding
  • carbohydrate binding
  • GO:0019862
  • GO:0030246
Galectin-2
  • Gal
9606
  • T cell homeostasis
  • carbohydrate binding
  • cell-cell adhesion
  • galactoside binding
  • galectin complex
  • positive regulation of apoptotic process
  • positive regulation of inflammatory response
  • GO:0016936
  • GO:0030246
  • GO:0043029
  • GO:0043065
  • GO:0050729
  • GO:0098609
  • GO:1990724
Displaying entries 41 - 50 of 2433 in total

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01