GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID	GO Labels	GO IDs
GL_001251	Alpha-xylosidase BoGH31A	A7LXT0	Bacteroides ovatus ATCC 8483	411476	alpha-D-xyloside xylohydrolase carbohydrate binding hydrolase activity, hydrolyzing O-glycosyl compounds plasma membrane symbiotic process benefiting host xyloglucan catabolic process	GO:0004553 GO:0005886 GO:0030246 GO:0061634 GO:0085030 GO:2000899
GL_000513	Galectin-9	P97840	Rattus norvegicus	10116	ERK1 and ERK2 cascade carbohydrate binding cellular response to type II interferon cellular response to virus cytoplasm cytosol disaccharide binding enzyme binding extracellular space female pregnancy galactoside binding inflammatory response maintenance of protein location maternal process involved in female pregnancy monoatomic ion transport natural killer cell tolerance induction negative regulation of CD4-positive, alpha-beta T cell proliferation negative regulation of activated T cell proliferation negative regulation of chemokine production negative regulation of gene expression negative regulation of inflammatory response negative regulation of mast cell degranulation negative regulation of natural killer cell activation negative regulation of natural killer cell degranulation negative regulation of natural killer cell mediated cytotoxicity negative regulation of tumor necrosis factor production negative regulation of type II interferon production nucleus p38MAPK cascade plasma membrane positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response positive regulation of CD4-positive, alpha-beta T cell proliferation positive regulation of ERK1 and ERK2 cascade positive regulation of SMAD protein signal transduction positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell positive regulation of T cell migration positive regulation of activated T cell autonomous cell death positive regulation of chemokine production positive regulation of cytokine production positive regulation of defense response to bacterium positive regulation of dendritic cell apoptotic process positive regulation of dendritic cell chemotaxis positive regulation of dendritic cell differentiation positive regulation of gene expression positive regulation of innate immune response positive regulation of interleukin-1 beta production positive regulation of interleukin-1 production positive regulation of interleukin-10 production positive regulation of interleukin-12 production positive regulation of interleukin-13 production positive regulation of interleukin-4 production positive regulation of interleukin-6 production positive regulation of interleukin-8 production positive regulation of macrophage activation positive regulation of monocyte chemotactic protein-1 production positive regulation of non-canonical NF-kappaB signal transduction positive regulation of regulatory T cell differentiation positive regulation of transforming growth factor beta production positive regulation of tumor necrosis factor production positive regulation of type II interferon production positive regulation of viral entry into host cell protein serine/threonine kinase activator activity receptor clustering regulation of natural killer cell differentiation response to interleukin-1 response to lipopolysaccharide signaling receptor binding toll-like receptor 3 signaling pathway transforming growth factor beta receptor signaling pathway	GO:0001819 GO:0002519 GO:0005102 GO:0005615 GO:0005634 GO:0005737 GO:0005829 GO:0005886 GO:0006811 GO:0006954 GO:0007179 GO:0007565 GO:0010628 GO:0010629 GO:0016936 GO:0019899 GO:0030246 GO:0032496 GO:0032682 GO:0032689 GO:0032720 GO:0032722 GO:0032729 GO:0032731 GO:0032732 GO:0032733 GO:0032735 GO:0032736 GO:0032753 GO:0032755 GO:0032757 GO:0032760 GO:0032815 GO:0032823 GO:0032834 GO:0034138 GO:0038066 GO:0043032 GO:0043113 GO:0043305 GO:0043322 GO:0043539 GO:0045089 GO:0045185 GO:0045591 GO:0045953 GO:0046007 GO:0046598 GO:0048030 GO:0050728 GO:0060135 GO:0060391 GO:0070241 GO:0070371 GO:0070374 GO:0070555 GO:0071346 GO:0071636 GO:0071639 GO:0098586 GO:1900426 GO:1901224 GO:2000406 GO:2000510 GO:2000562 GO:2000563 GO:2000670 GO:2001190 GO:2001200
GL_000501	Galectin-4	P56470	Homo sapiens	9606	antibacterial peptide biosynthetic process carbohydrate binding cell adhesion collagen-containing extracellular matrix cytosol extracellular space galactoside binding plasma membrane	GO:0002780 GO:0005615 GO:0005829 GO:0005886 GO:0007155 GO:0016936 GO:0030246 GO:0062023
GL_000974	Protein FAM3C	Q7ZYY4	Danio rerio	7955	carbohydrate binding extracellular space	GO:0005615 GO:0030246
GL_001404	Chondroitin sulfate ABC endolyase	P59807	Proteus vulgaris	585	carbohydrate binding carbohydrate metabolic process chondroitin-sulfate-ABC endolyase activity extracellular region glycosaminoglycan catabolic process metal ion binding periplasmic space	GO:0005576 GO:0005975 GO:0006027 GO:0030246 GO:0034000 GO:0042597 GO:0046872
GL_001618	Glucans biosynthesis protein G	Q87UY0	Pseudomonas syringae pv. tomato str. DC3000	223283	carbohydrate binding catalytic activity glucan biosynthetic process periplasmic space	GO:0003824 GO:0009250 GO:0030246 GO:0042597
GL_000031	Agglutinin alpha chain (Fragment)	P84762	Artocarpus tonkinensis	3492	IgA binding carbohydrate binding	GO:0019862 GO:0030246
GL_002226	Capsid protein	Q6B7R3	Norovirus NLV/IF1998/2003/Iraq	286545
GL_002191	Spike glycoprotein (Fragment)	Q1HLC5	Bovine coronavirus	11128	endocytosis involved in viral entry into host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane host cell plasma membrane membrane receptor-mediated virion attachment to host cell viral envelope virion membrane	GO:0016020 GO:0019031 GO:0019064 GO:0020002 GO:0039654 GO:0046813 GO:0055036 GO:0075509
GL_000814	Nigrin b	P33183	Sambucus nigra	4202	carbohydrate binding defense response negative regulation of translation rRNA N-glycosylase activity toxin activity	GO:0006952 GO:0017148 GO:0030246 GO:0030598 GO:0090729