GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID ▼	GO Labels	GO IDs
GL_001727	Neutral alpha-glucosidase AB	P79403	Sus scrofa	9823	Golgi apparatus N-glycan processing alpha-glucosidase activity carbohydrate binding carbohydrate metabolic process glucan 1,3-alpha-glucosidase activity glucosidase II complex intracellular membrane-bounded organelle melanosome	GO:0005794 GO:0005975 GO:0006491 GO:0017177 GO:0030246 GO:0033919 GO:0042470 GO:0043231 GO:0090599
GL_000386	Ficolin-1	Q29042	Sus scrofa	9823	antigen binding carbohydrate binding carbohydrate derivative binding collagen trimer collagen-containing extracellular matrix complement activation, lectin pathway extracellular space metal ion binding plasma membrane signaling receptor binding	GO:0001867 GO:0003823 GO:0005102 GO:0005581 GO:0005615 GO:0005886 GO:0030246 GO:0046872 GO:0062023 GO:0097367
GL_001895	Zona pellucida sperm-binding protein 3	P42098	Sus scrofa	9823	acrosin binding binding of sperm to zona pellucida blastocyst formation carbohydrate binding collagen-containing extracellular matrix egg coat egg coat formation extracellular matrix extracellular space humoral immune response mediated by circulating immunoglobulin negative regulation of DNA-templated transcription negative regulation of binding of sperm to zona pellucida oocyte development plasma membrane positive regulation of DNA-templated transcription positive regulation of T cell proliferation positive regulation of acrosomal vesicle exocytosis positive regulation of acrosome reaction positive regulation of antral ovarian follicle growth positive regulation of humoral immune response positive regulation of inflammatory response positive regulation of interleukin-4 production positive regulation of leukocyte migration positive regulation of ovarian follicle development positive regulation of type II interferon production positive regulation of type IV hypersensitivity receptor ligand activity structural constituent of egg coat	GO:0001809 GO:0001825 GO:0002455 GO:0002687 GO:0002922 GO:0005615 GO:0005886 GO:0007339 GO:0030246 GO:0031012 GO:0032190 GO:0032729 GO:0032753 GO:0035803 GO:0035804 GO:0035805 GO:0042102 GO:0045892 GO:0045893 GO:0048018 GO:0048599 GO:0050729 GO:0062023 GO:2000344 GO:2000360 GO:2000368 GO:2000386 GO:2000388
GL_002082	Heparin-binding protein WGA16	A0A0A8IK66	Sus scrofa	9823
GL_000191	C-type lectin domain family 5 member A	Q9GLF3	Sus scrofa	9823	carbohydrate binding cell surface cytosol innate immune response myeloid cell differentiation negative regulation of apoptotic process negative regulation of myeloid cell apoptotic process osteoblast development plasma membrane positive regulation of cytokine production virus receptor activity	GO:0001618 GO:0001819 GO:0002076 GO:0005829 GO:0005886 GO:0009986 GO:0030099 GO:0030246 GO:0033033 GO:0043066 GO:0045087
GL_000262	Calreticulin	P28491	Sus scrofa	9823	MHC class I peptide loading complex calcium ion binding carbohydrate binding cellular senescence complement component C1q complex binding cortical actin cytoskeleton organization cortical granule cytolytic granule cytosol endoplasmic reticulum membrane endoplasmic reticulum quality control compartment external side of plasma membrane extracellular space integrin binding mRNA binding negative regulation of intracellular steroid hormone receptor signaling pathway negative regulation of neuron differentiation negative regulation of retinoic acid receptor signaling pathway negative regulation of transcription by RNA polymerase II negative regulation of translation negative regulation of trophoblast cell migration nuclear androgen receptor binding nuclear envelope nuclear export signal receptor activity peptide antigen assembly with MHC class I protein complex perinuclear region of cytoplasm polysome positive regulation of cell cycle positive regulation of cell population proliferation positive regulation of dendritic cell chemotaxis positive regulation of endothelial cell migration positive regulation of gene expression positive regulation of non-canonical NF-kappaB signal transduction positive regulation of phagocytosis positive regulation of substrate adhesion-dependent cell spreading protein export from nucleus protein folding protein localization to nucleus protein stabilization regulation of meiotic nuclear division sarcoplasmic reticulum lumen ubiquitin protein ligase binding ubiquitin-dependent ERAD pathway unfolded protein binding	GO:0000122 GO:0001849 GO:0002502 GO:0003729 GO:0005049 GO:0005178 GO:0005509 GO:0005615 GO:0005635 GO:0005789 GO:0005829 GO:0005844 GO:0006457 GO:0006611 GO:0008284 GO:0009897 GO:0010595 GO:0010628 GO:0017148 GO:0030246 GO:0030433 GO:0030866 GO:0031625 GO:0033018 GO:0033144 GO:0034504 GO:0040020 GO:0042824 GO:0044194 GO:0044322 GO:0045665 GO:0045787 GO:0048387 GO:0048471 GO:0050681 GO:0050766 GO:0050821 GO:0051082 GO:0060473 GO:0090398 GO:1900026 GO:1901164 GO:1901224 GO:2000510
GL_000839	Oxidized low-density lipoprotein receptor 1	Q9TTK7	Sus scrofa	9823	carbohydrate binding extracellular region immune system process inflammatory response leukocyte cell-cell adhesion lipoprotein metabolic process low-density lipoprotein particle receptor activity membrane raft plasma membrane positive regulation of superoxide anion generation receptor complex vasoconstriction	GO:0002376 GO:0005041 GO:0005576 GO:0005886 GO:0006954 GO:0007159 GO:0030246 GO:0032930 GO:0042157 GO:0042310 GO:0043235 GO:0045121
GL_000310	Chitinase-3-like protein 1	Q29411	Sus scrofa	9823	activation of NF-kappaB-inducing kinase activity apoptotic process carbohydrate binding carbohydrate metabolic process cellular response to tumor necrosis factor chitin binding chitin catabolic process cytoplasm endoplasmic reticulum extracellular region extracellular space inflammatory response lung development perinuclear region of cytoplasm positive regulation of ERK1 and ERK2 cascade positive regulation of angiogenesis positive regulation of interleukin-8 production positive regulation of peptidyl-threonine phosphorylation positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction response to interleukin-1 response to interleukin-6 response to mechanical stimulus response to tumor necrosis factor	GO:0005576 GO:0005615 GO:0005737 GO:0005783 GO:0005975 GO:0006032 GO:0006915 GO:0006954 GO:0007250 GO:0008061 GO:0009612 GO:0010800 GO:0030246 GO:0030324 GO:0032757 GO:0034612 GO:0045766 GO:0048471 GO:0051897 GO:0070374 GO:0070555 GO:0070741 GO:0071356
GL_000391	Ficolin-2	Q29041	Sus scrofa	9823	antigen binding carbohydrate binding carbohydrate derivative binding collagen trimer collagen-containing extracellular matrix complement activation, lectin pathway extracellular space metal ion binding signaling receptor binding	GO:0001867 GO:0003823 GO:0005102 GO:0005581 GO:0005615 GO:0030246 GO:0046872 GO:0062023 GO:0097367
GL_001367	Beta-glucuronidase	Q4FAT7	Sus scrofa	9823	beta-glucuronidase activity carbohydrate binding carbohydrate metabolic process chondroitin sulfate catabolic process extracellular space glucuronoside catabolic process heparan sulfate proteoglycan catabolic process hyaluronan catabolic process lysosomal lumen protein domain specific binding signaling receptor binding	GO:0004566 GO:0005102 GO:0005615 GO:0005975 GO:0019391 GO:0019904 GO:0030200 GO:0030207 GO:0030214 GO:0030246 GO:0043202