GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin ▼	Lectin Name	UniProt ID	Species	Taxonomy ID	GO Labels	GO IDs
GL_002353	Botulinum neurotoxin type D	P19321	Clostridium botulinum D phage	29342	extracellular region ganglioside GT1b binding metalloendopeptidase activity protein transmembrane transporter activity proteolysis toxin activity zinc ion binding	GO:0004222 GO:0005576 GO:0006508 GO:0008270 GO:0008320 GO:0090729 GO:1905576
GL_002352	Botulinum neurotoxin type C	P18640	Clostridium phage c-st	12336	extracellular region ganglioside binding membrane protein proteolysis metalloendopeptidase activity negative regulation by symbiont of host neurotransmitter secretion negative regulation of calcium ion-dependent exocytosis protein transmembrane transporter activity toxin activity zinc ion binding	GO:0004222 GO:0005576 GO:0008270 GO:0008320 GO:0033619 GO:0035594 GO:0044762 GO:0045955 GO:0090729
GL_002351	Toxin A	P16154	Clostridioides difficile	1496	cysteine-type peptidase activity extracellular region glycosyltransferase activity host cell cytosol host cell endosome membrane host cell plasma membrane lipid binding membrane metal ion binding proteolysis toxin activity	GO:0005576 GO:0006508 GO:0008234 GO:0008289 GO:0016020 GO:0016757 GO:0020002 GO:0044164 GO:0044175 GO:0046872 GO:0090729
GL_002350	Hemagglutinin-esterase	P15776	Bovine coronavirus Mebus	11132	fusion of virus membrane with host plasma membrane host cell plasma membrane host cell surface receptor binding identical protein binding membrane negative regulation of immune system process protein homodimerization activity receptor-mediated virion attachment to host cell sialate 4-O-acetylesterase activity sialate 9-O-acetylesterase activity sialate O-acetylesterase activity signaling receptor binding viral envelope virion membrane	GO:0001681 GO:0002683 GO:0005102 GO:0016020 GO:0019031 GO:0019064 GO:0020002 GO:0042802 GO:0042803 GO:0046789 GO:0046813 GO:0055036 GO:0106330 GO:0106331
GL_002349	Concanavalin-A	P14894	Canavalia gladiata	3824	mannose binding metal ion binding monosaccharide binding negative regulation of DNA-templated transcription positive regulation of cell division positive regulation of mitotic nuclear division regulation of defense response to virus	GO:0005537 GO:0045840 GO:0045892 GO:0046872 GO:0048029 GO:0050688 GO:0051781
GL_002348	K88 fimbrial protein AD	P14191	Escherichia coli	562	pilus	GO:0009289
GL_002347	Neural cell adhesion molecule 1	P13591	Homo sapiens	9606	Golgi membrane cell adhesion cell surface collagen-containing extracellular matrix commissural neuron axon guidance cytosol epithelial to mesenchymal transition external side of plasma membrane extracellular region membrane plasma membrane regulation of semaphorin-plexin signaling pathway virus receptor activity	GO:0000139 GO:0001618 GO:0001837 GO:0005576 GO:0005829 GO:0005886 GO:0007155 GO:0009897 GO:0009986 GO:0016020 GO:0062023 GO:0071679 GO:2001260
GL_002346	Tail spike protein	P12528	Lederbergvirus P22	10754	adhesion receptor-mediated virion attachment to host cell disruption by virus of host envelope lipopolysaccharide during virus entry disruption of host cell envelope during viral entry endo-1,3-alpha-L-rhamnosidase activity entry into host metabolic process virion attachment to host cell virus tail, fiber	GO:0008152 GO:0019062 GO:0044409 GO:0052775 GO:0098024 GO:0098671 GO:0098994 GO:0098995
GL_002345	Outer capsid protein VP4	P12473	Simian rotavirus A strain RRV	444185	host cell endoplasmic reticulum-Golgi intermediate compartment host cell plasma membrane host cell rough endoplasmic reticulum host cytoskeleton membrane permeabilization of host organelle membrane involved in viral entry into host cell viral entry via permeabilization of inner membrane viral outer capsid virion attachment to host cell	GO:0016020 GO:0019062 GO:0020002 GO:0039624 GO:0039665 GO:0044163 GO:0044168 GO:0044172 GO:0099008
GL_002344	Mannose/glucose-specific lectin alpha 1 chain	P12306	Lathyrus ochrus	3858	mannose binding	GO:0005537