GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID ▼	Species	Taxonomy ID	GO Labels	GO IDs
GL_000174	C-type lectin domain family 4 member A	Q9UMR7	Homo sapiens	9606	CD8-positive, alpha-beta T cell activation adaptive immune response antifungal innate immune response antigen processing and presentation of exogenous peptide antigen via MHC class I calcium ion binding carbohydrate binding cell adhesion cell surface receptor signaling pathway external side of plasma membrane mannose binding negative regulation of cytokine production negative regulation of tumor necrosis factor production plasma membrane plasmacytoid dendritic cell antigen processing and presentation transmembrane signaling receptor activity	GO:0001818 GO:0002250 GO:0002470 GO:0004888 GO:0005509 GO:0005537 GO:0005886 GO:0007155 GO:0007166 GO:0009897 GO:0030246 GO:0032720 GO:0036037 GO:0042590 GO:0061760
GL_000180	C-type lectin domain family 4 member E	Q9ULY5	Homo sapiens	9606	Fc-gamma receptor signaling pathway T cell differentiation involved in immune response antifungal innate immune response calcium ion binding carbohydrate binding cell projection defense response to bacterium external side of plasma membrane glycolipid binding innate immune response membrane pattern recognition receptor activity pattern recognition receptor signaling pathway phagocytic cup phagocytic vesicle membrane plasma membrane positive regulation of cytokine production	GO:0001819 GO:0001891 GO:0002221 GO:0002292 GO:0005509 GO:0005886 GO:0009897 GO:0016020 GO:0030246 GO:0030670 GO:0038094 GO:0038187 GO:0042742 GO:0042995 GO:0045087 GO:0051861 GO:0061760
GL_002411	Paired immunoglobulin-like type 2 receptor alpha	Q9UKJ1	Homo sapiens	9606	MHC class I protein binding extracellular exosome plasma membrane signal transduction	GO:0005886 GO:0007165 GO:0042288 GO:0070062
GL_002410	Paired immunoglobulin-like type 2 receptor beta	Q9UKJ0	Homo sapiens	9606	MHC class I protein binding activation of transmembrane receptor protein tyrosine kinase activity plasma membrane transmembrane receptor protein tyrosine kinase signaling pathway	GO:0005886 GO:0007169 GO:0007171 GO:0042288
GL_000373	F-box only protein 2	Q9UK22	Homo sapiens	9606	SCF ubiquitin ligase complex SCF-dependent proteasomal ubiquitin-dependent protein catabolic process amyloid-beta binding carbohydrate binding cytoplasm cytosol denatured protein binding dendritic spine endoplasmic reticulum extrinsic component of postsynaptic membrane glutamatergic synapse glycoprotein catabolic process negative regulation of cell population proliferation protein modification process protein ubiquitination proteolysis regulation of protein catabolic process at postsynapse, modulating synaptic transmission regulation of protein ubiquitination ubiquitin-dependent ERAD pathway ubiquitin-protein transferase activity	GO:0001540 GO:0004842 GO:0005737 GO:0005783 GO:0005829 GO:0006508 GO:0006516 GO:0008285 GO:0016567 GO:0019005 GO:0030246 GO:0030433 GO:0031146 GO:0031249 GO:0031396 GO:0036211 GO:0043197 GO:0098890 GO:0098978 GO:0099576
GL_000189	C-type lectin domain family 4 member K	Q9UJ71	Homo sapiens	9606	carbohydrate binding clathrin-coated endocytic vesicle membrane defense response to virus early endosome membrane endocytic vesicle external side of plasma membrane mannose binding plasma membrane	GO:0005537 GO:0005886 GO:0009897 GO:0030139 GO:0030246 GO:0030669 GO:0031901 GO:0051607
GL_000466	Galactoside-binding soluble lectin 13	Q9UHV8	Homo sapiens	9606	apoptotic process carbohydrate binding cytoplasm lysophospholipase activity nuclear body nuclear matrix nucleoplasm phospholipid metabolic process	GO:0004622 GO:0005654 GO:0005737 GO:0006644 GO:0006915 GO:0016363 GO:0016604 GO:0030246
GL_000153	C-type lectin domain family 2 member D	Q9UHP7	Homo sapiens	9606	carbohydrate binding cell surface cell surface receptor signaling pathway endoplasmic reticulum external side of plasma membrane membrane plasma membrane transmembrane signaling receptor activity	GO:0004888 GO:0005783 GO:0005886 GO:0007166 GO:0009897 GO:0009986 GO:0016020 GO:0030246
GL_000551	Inactive cell surface hyaluronidase CEMIP2	Q9UHN6	Homo sapiens	9606	angiogenesis cadherin binding calcium ion binding carbohydrate binding cytosol extracellular exosome hyaluronan catabolic process intracellular membrane-bounded organelle membrane nucleolus plasma membrane regulation of sprouting angiogenesis	GO:0001525 GO:0005509 GO:0005730 GO:0005829 GO:0005886 GO:0016020 GO:0030214 GO:0030246 GO:0043231 GO:0045296 GO:0070062 GO:1903670
GL_000239	C-type mannose receptor 2	Q9UBG0	Homo sapiens	9606	carbohydrate binding collagen binding collagen catabolic process endocytosis focal adhesion membrane osteoblast differentiation signaling receptor activity	GO:0001649 GO:0005518 GO:0005925 GO:0006897 GO:0016020 GO:0030246 GO:0030574 GO:0038023