GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database Last Updated
MCAW-DB July 10, 2019
UniLectin June 14, 2023
UniProt February 16, 2024
Lectin Frontier DataBase (LfDB) February 16, 2024
CarboGrove June 14, 2023
GlyCosmos Lectin Lectin Name UniProt ID Monosaccharide Specificities Species Taxonomy ID ▼ GO Labels GO IDs
Pulmonary surfactant-associated protein A
9986
  • carbohydrate binding
  • collagen trimer
  • extracellular region
  • metal ion binding
  • respiratory gaseous exchange by respiratory system
  • GO:0005576
  • GO:0005581
  • GO:0007585
  • GO:0030246
  • GO:0046872
E-selectin
9986
  • carbohydrate binding
  • cell adhesion
  • metal ion binding
  • plasma membrane
  • positive regulation of leukocyte tethering or rolling
  • GO:0005886
  • GO:0007155
  • GO:0030246
  • GO:0046872
  • GO:1903238
Calreticulin
9986
  • calcium ion binding
  • carbohydrate binding
  • cell surface
  • cortical granule
  • cytolytic granule
  • cytosol
  • extracellular region
  • protein folding
  • protein stabilization
  • sarcoplasmic reticulum
  • sarcoplasmic reticulum lumen
  • unfolded protein binding
  • GO:0005509
  • GO:0005576
  • GO:0005829
  • GO:0006457
  • GO:0009986
  • GO:0016529
  • GO:0030246
  • GO:0033018
  • GO:0044194
  • GO:0050821
  • GO:0051082
  • GO:0060473
Zona pellucida sperm-binding protein 3 (Fragment)
9986
  • binding of sperm to zona pellucida
  • blastocyst formation
  • carbohydrate binding
  • collagen-containing extracellular matrix
  • egg coat
  • egg coat formation
  • extracellular space
  • humoral immune response mediated by circulating immunoglobulin
  • negative regulation of DNA-templated transcription
  • negative regulation of binding of sperm to zona pellucida
  • oocyte development
  • plasma membrane
  • positive regulation of DNA-templated transcription
  • positive regulation of T cell proliferation
  • positive regulation of acrosomal vesicle exocytosis
  • positive regulation of acrosome reaction
  • positive regulation of antral ovarian follicle growth
  • positive regulation of humoral immune response
  • positive regulation of inflammatory response
  • positive regulation of interleukin-4 production
  • positive regulation of leukocyte migration
  • positive regulation of ovarian follicle development
  • positive regulation of type II interferon production
  • positive regulation of type IV hypersensitivity
  • receptor ligand activity
  • structural constituent of egg coat
  • GO:0001809
  • GO:0001825
  • GO:0002455
  • GO:0002687
  • GO:0002922
  • GO:0005615
  • GO:0005886
  • GO:0007339
  • GO:0030246
  • GO:0032729
  • GO:0032753
  • GO:0035803
  • GO:0035804
  • GO:0035805
  • GO:0042102
  • GO:0045892
  • GO:0045893
  • GO:0048018
  • GO:0048599
  • GO:0050729
  • GO:0062023
  • GO:2000344
  • GO:2000360
  • GO:2000368
  • GO:2000386
  • GO:2000388
Galectin-3
9986
  • IgE binding
  • RNA splicing
  • carbohydrate binding
  • cell differentiation
  • cytoplasm
  • extracellular region
  • innate immune response
  • mRNA processing
  • spliceosomal complex
  • GO:0005576
  • GO:0005681
  • GO:0005737
  • GO:0006397
  • GO:0008380
  • GO:0019863
  • GO:0030154
  • GO:0030246
  • GO:0045087
Sucrase-isomaltase, intestinal
9986
  • apical plasma membrane
  • carbohydrate binding
  • carbohydrate metabolic process
  • oligo-1,6-glucosidase activity
  • sucrose alpha-glucosidase activity
  • GO:0004574
  • GO:0004575
  • GO:0005975
  • GO:0016324
  • GO:0030246
Secretory phospholipase A2 receptor
9986
  • carbohydrate binding
  • extracellular region
  • oxidative stress-induced premature senescence
  • phospholipase binding
  • plasma membrane
  • positive regulation of DNA damage response, signal transduction by p53 class mediator
  • positive regulation of arachidonic acid secretion
  • positive regulation of cytokine production
  • reactive oxygen species metabolic process
  • receptor-mediated endocytosis
  • replicative senescence
  • signaling receptor activity
  • GO:0001819
  • GO:0005576
  • GO:0005886
  • GO:0006898
  • GO:0030246
  • GO:0038023
  • GO:0043274
  • GO:0043517
  • GO:0072593
  • GO:0090238
  • GO:0090399
  • GO:0090403
Oxidized low-density lipoprotein receptor 1
9986
  • carbohydrate binding
  • cell adhesion
  • extracellular region
  • immune system process
  • inflammatory response
  • membrane raft
  • plasma membrane
  • GO:0002376
  • GO:0005576
  • GO:0005886
  • GO:0006954
  • GO:0007155
  • GO:0030246
  • GO:0045121
Lectin alpha chain
99571
  • carbohydrate binding
  • mannose binding
  • metal ion binding
  • toxin activity
  • GO:0005537
  • GO:0030246
  • GO:0046872
  • GO:0090729
Pulmonary surfactant-associated protein A
9940
  • carbohydrate binding
  • collagen trimer
  • extracellular region
  • metal ion binding
  • respiratory gaseous exchange by respiratory system
  • GO:0005576
  • GO:0005581
  • GO:0007585
  • GO:0030246
  • GO:0046872
Displaying entries 1 - 10 of 2433 in total

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01