GlyCosmos Portal

GlyCosmos Lectins

Integrated list of Lectins, including proteins with carbohydrate binding function obtained from UniProt and lectin data from Lectin Frontier DataBase (LfDB), UniLectin and CarboGrove. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Source	Last Updated
MCAW	July 10, 2019
UniLectin	June 14, 2023
UniProt	March 3, 2025
Lectin Frontier DataBase (LfDB)	April 6, 2018
CarboGrove	June 14, 2023

Displaying entries **26 - 50** of **297** in total

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GlyCosmos Lectin	Lectin Name	UniProt ID	PDB IDs	Organism	Taxonomy ID	Gene Ontology	Gene Ontology ID ▲
GL_000888	Polypeptide N-acetylgalactosaminyltransferase 10	Q86SR1	2D7I 2D7R	Homo sapiens (human)	9606	Golgi apparatus Golgi membrane O-glycan processing carbohydrate binding metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation	GO:0000139 GO:0004653 GO:0005794 GO:0006493 GO:0016266 GO:0030246 GO:0046872
GL_000895	Polypeptide N-acetylgalactosaminyltransferase 12	Q8IXK2	6PXU	Homo sapiens (human)	9606	Golgi apparatus Golgi membrane O-glycan processing carbohydrate binding metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation	GO:0000139 GO:0004653 GO:0005794 GO:0006493 GO:0016266 GO:0030246 GO:0046872
GL_000931	Polypeptide N-acetylgalactosaminyltransferase 9	Q9HCQ5		Homo sapiens (human)	9606	Golgi apparatus Golgi membrane O-glycan processing carbohydrate binding metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation	GO:0000139 GO:0004653 GO:0005794 GO:0006493 GO:0016266 GO:0030246 GO:0046872
GL_000957	Probable polypeptide N-acetylgalactosaminyltransferase 8	Q9NY28		Homo sapiens (human)	9606	Golgi apparatus Golgi membrane O-glycan processing carbohydrate binding metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation	GO:0000139 GO:0004653 GO:0005794 GO:0006493 GO:0016266 GO:0030246 GO:0046872
GL_000900	Polypeptide N-acetylgalactosaminyltransferase 14	Q96FL9		Homo sapiens (human)	9606	Golgi apparatus Golgi membrane O-glycan processing carbohydrate binding metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation	GO:0000139 GO:0004653 GO:0005794 GO:0006493 GO:0016266 GO:0030246 GO:0046872
GL_000904	Polypeptide N-acetylgalactosaminyltransferase 16	Q8N428		Homo sapiens (human)	9606	Golgi apparatus Golgi membrane carbohydrate binding metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation via serine protein O-linked glycosylation via threonine protein O-linked glycosylation	GO:0000139 GO:0004653 GO:0005794 GO:0006493 GO:0018242 GO:0018243 GO:0030246 GO:0046872
GL_000933	Polypeptide N-acetylgalactosaminyltransferase-like 6	Q49A17		Homo sapiens (human)	9606	Golgi apparatus Golgi membrane carbohydrate binding metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation via threonine protein O-linked glycosylation	GO:0000139 GO:0004653 GO:0005794 GO:0006493 GO:0018243 GO:0030246 GO:0046872
GL_000908	Polypeptide N-acetylgalactosaminyltransferase 18	Q6P9A2		Homo sapiens (human)	9606	Golgi apparatus Golgi membrane carbohydrate binding metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation	GO:0000139 GO:0004653 GO:0005794 GO:0006493 GO:0030246 GO:0046872
GL_000907	Polypeptide N-acetylgalactosaminyltransferase 17	Q6IS24		Homo sapiens (human)	9606	Golgi apparatus Golgi membrane carbohydrate binding metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation	GO:0000139 GO:0004653 GO:0005794 GO:0006493 GO:0030246 GO:0046872
GL_000919	Polypeptide N-acetylgalactosaminyltransferase 4	Q8N4A0	5NQA 6H0B	Homo sapiens (human)	9606	Golgi membrane O-glycan processing carbohydrate binding extracellular exosome manganese ion binding perinuclear region of cytoplasm polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation via serine protein O-linked glycosylation via threonine protein O-linked glycosylation	GO:0000139 GO:0004653 GO:0006493 GO:0016266 GO:0018242 GO:0018243 GO:0030145 GO:0030246 GO:0048471 GO:0070062
GL_001174	Vesicular integral-membrane protein VIP36	Q12907		Homo sapiens (human)	9606	COPII-coated ER to Golgi transport vesicle Golgi apparatus Golgi membrane carbohydrate binding cell surface endoplasmic reticulum membrane endoplasmic reticulum to Golgi vesicle-mediated transport endoplasmic reticulum-Golgi intermediate compartment membrane endoplasmic reticulum-Golgi intermediate compartment extracellular exosome extracellular space heat shock protein binding mannose binding metal ion binding plasma membrane positive regulation of phagocytosis protein transport retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	GO:0000139 GO:0005537 GO:0005615 GO:0005789 GO:0005793 GO:0005794 GO:0005886 GO:0006888 GO:0006890 GO:0009986 GO:0015031 GO:0030134 GO:0030246 GO:0031072 GO:0033116 GO:0046872 GO:0050766 GO:0070062
GL_002053	Protein ERGIC-53	P49257	3A4U 3LCP 3WHT 3WHU 3WNX 4GKX 4GKY 4YGB 4YGC 4YGD 4YGE 8JP4 8JP5 8JP6 8JP7 8JP8 8JP9 8JPG	Homo sapiens (human)	9606	COPII-coated ER to Golgi transport vesicle ER to Golgi transport vesicle membrane Golgi membrane Golgi organization blood coagulation collagen-containing extracellular matrix endoplasmic reticulum membrane endoplasmic reticulum organization endoplasmic reticulum to Golgi vesicle-mediated transport endoplasmic reticulum-Golgi intermediate compartment membrane endoplasmic reticulum-Golgi intermediate compartment endoplasmic reticulum extracellular exosome mannose binding membrane metal ion binding negative regulation of protein targeting to mitochondrion positive regulation of organelle organization protein folding protein transport sarcomere unfolded protein binding	GO:0000139 GO:0005537 GO:0005783 GO:0005789 GO:0005793 GO:0006457 GO:0006888 GO:0007029 GO:0007030 GO:0007596 GO:0010638 GO:0012507 GO:0015031 GO:0016020 GO:0030017 GO:0030134 GO:0033116 GO:0046872 GO:0051082 GO:0062023 GO:0070062 GO:1903215
GL_002077	VIP36-like protein	Q9H0V9		Homo sapiens (human)	9606	COPII-coated ER to Golgi transport vesicle Golgi apparatus Golgi membrane endoplasmic reticulum membrane endoplasmic reticulum to Golgi vesicle-mediated transport endoplasmic reticulum-Golgi intermediate compartment mannose binding membrane metal ion binding protein folding protein transport	GO:0000139 GO:0005537 GO:0005789 GO:0005793 GO:0005794 GO:0006457 GO:0006888 GO:0015031 GO:0016020 GO:0030134 GO:0046872
GL_002057	Protein ERGIC-53-like	Q9HAT1		Homo sapiens (human)	9606	COPII-coated ER to Golgi transport vesicle Golgi membrane collagen-containing extracellular matrix endoplasmic reticulum membrane endoplasmic reticulum to Golgi vesicle-mediated transport endoplasmic reticulum-Golgi intermediate compartment membrane endoplasmic reticulum-Golgi intermediate compartment mannose binding	GO:0000139 GO:0005537 GO:0005789 GO:0005793 GO:0006888 GO:0030134 GO:0033116 GO:0062023
GL_000152	C-type lectin domain family 2 member B	Q92478		Homo sapiens (human)	9606	Golgi membrane NK T cell activation carbohydrate binding external side of plasma membrane identical protein binding plasma membrane receptor ligand activity	GO:0000139 GO:0005886 GO:0009897 GO:0030246 GO:0042802 GO:0048018 GO:0051132
GL_000985	Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1	Q8WZA1	5GGF 5GGG 5GGI 5GGJ 5GGK 5GGL 5GGN 5GGO 5GGP 5XFC	Homo sapiens (human)	9606	Golgi membrane O-glycan processing acetylglucosaminyltransferase activity basement membrane organization beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity carbohydrate binding dentate gyrus development gene expression localization of cell manganese ion binding membrane myelination protein O-linked glycosylation protein O-linked mannosylation reactive gliosis sensory perception of sound	GO:0000139 GO:0006493 GO:0007605 GO:0008375 GO:0010467 GO:0016020 GO:0016266 GO:0021542 GO:0030145 GO:0030246 GO:0035269 GO:0042552 GO:0047223 GO:0051674 GO:0071711 GO:0150103
GL_003145	Protein phosphatase 1 regulatory subunit 3C	Q9UQK1	7QF7 7QFA 7QFB 7QM2	Homo sapiens (human)	9606	cytosol glycogen binding glycogen biosynthetic process glycogen metabolic process molecular adaptor activity protein phosphatase 1 binding protein phosphatase binding protein phosphatase type 1 complex protein serine/threonine phosphatase activity regulation of glycogen biosynthetic process	GO:0000164 GO:0004722 GO:0005829 GO:0005977 GO:0005978 GO:0005979 GO:0008157 GO:0019903 GO:0060090 GO:2001069
GL_003161	Protein phosphatase 1 regulatory subunit 3D	O95685		Homo sapiens (human)	9606	glycogen binding glycogen granule glycogen metabolic process protein phosphatase 1 binding protein phosphatase type 1 complex protein serine/threonine phosphatase activity regulation of glycogen biosynthetic process regulation of glycogen catabolic process	GO:0000164 GO:0004722 GO:0005977 GO:0005979 GO:0005981 GO:0008157 GO:0042587 GO:2001069
GL_003157	Protein phosphatase 1 regulatory subunit 3A	Q16821	5ZQV	Homo sapiens (human)	9606	glycogen binding glycogen metabolic process membrane protein phosphatase 1 binding protein phosphatase type 1 complex regulation of glycogen biosynthetic process	GO:0000164 GO:0005977 GO:0005979 GO:0008157 GO:0016020 GO:2001069
GL_003160	Protein phosphatase 1 regulatory subunit 3B	Q86XI6	2EEF 5ZT0	Homo sapiens (human)	9606	[phosphorylase] phosphatase activity glycogen binding glycogen granule glycogen metabolic process negative regulation of glycogen catabolic process positive regulation of glycogen biosynthetic process protein phosphatase 1 binding protein phosphatase regulator activity protein phosphatase type 1 complex regulation of glycogen biosynthetic process	GO:0000164 GO:0005977 GO:0005979 GO:0008157 GO:0019888 GO:0042587 GO:0045725 GO:0045818 GO:0050196 GO:2001069
GL_003155	Protein phosphatase 1 regulatory subunit 3E	Q9H7J1		Homo sapiens (human)	9606	[phosphorylase] phosphatase activity glycogen binding glycogen granule glycogen metabolic process positive regulation of glycogen biosynthetic process protein phosphatase 1 binding protein phosphatase type 1 complex regulation of glycogen biosynthetic process	GO:0000164 GO:0005977 GO:0005979 GO:0008157 GO:0042587 GO:0045725 GO:0050196 GO:2001069
GL_003163	Protein phosphatase 1 regulatory subunit 3G	B7ZBB8		Homo sapiens (human)	9606	glucose homeostasis glycogen binding glycogen biosynthetic process positive regulation of glycogen biosynthetic process protein phosphatase 1 binding protein phosphatase type 1 complex regulation of glycogen biosynthetic process	GO:0000164 GO:0005978 GO:0005979 GO:0008157 GO:0042593 GO:0045725 GO:2001069
GL_003151	Protein phosphatase 1 regulatory subunit 3F	Q6ZSY5		Homo sapiens (human)	9606	glycogen binding membrane protein phosphatase 1 binding protein phosphatase binding protein phosphatase type 1 complex regulation of glycogen (starch) synthase activity regulation of glycogen biosynthetic process	GO:0000164 GO:0005979 GO:0008157 GO:0016020 GO:0019903 GO:2000465 GO:2001069
GL_005296	Contactin-2	Q02246	2OM5 8K3J 8K53 9BA4 9BA5	Homo sapiens (human)	9606	G protein-coupled adenosine receptor signaling pathway adult walking behavior axon guidance axon initial segment axon axonal fasciculation carbohydrate binding cell adhesion cell surface cell-cell adhesion mediator activity central nervous system myelination cerebral cortex GABAergic interneuron migration clustering of voltage-gated potassium channels dendrite self-avoidance establishment of localization in cell establishment of protein localization to juxtaparanode region of axon fat cell differentiation homophilic cell adhesion via plasma membrane adhesion molecules juxtaparanode region of axon learning microtubule cytoskeleton organization myelin sheath negative regulation of neuron differentiation neuronal cell body node of Ranvier plasma membrane positive regulation of adenosine receptor signaling pathway positive regulation of protein processing postsynaptic membrane presynaptic membrane organization protein localization to juxtaparanode region of axon protein processing receptor internalization reduction of food intake in response to dietary excess regulation of astrocyte differentiation regulation of axon diameter regulation of cell morphogenesis regulation of neuronal synaptic plasticity side of membrane synapse organization synapse	GO:0000226 GO:0001973 GO:0002023 GO:0005886 GO:0007155 GO:0007156 GO:0007411 GO:0007413 GO:0007612 GO:0007628 GO:0009986 GO:0010954 GO:0016485 GO:0021853 GO:0022010 GO:0022604 GO:0030246 GO:0030424 GO:0031133 GO:0031623 GO:0033268 GO:0043025 GO:0043194 GO:0043209 GO:0044224 GO:0045163 GO:0045202 GO:0045211 GO:0045444 GO:0045665 GO:0048168 GO:0048710 GO:0050808 GO:0051649 GO:0060168 GO:0070593 GO:0071205 GO:0071206 GO:0097090 GO:0098552 GO:0098632
GL_003353	Pyruvate kinase PKLR	P30613	2VGB 2VGF 2VGG 2VGI 4IMA 4IP7 5SC8 5SC9 5SCA 5SCB 5SCC 5SCD 5SCE 5SCF 5SCG 5SCH 5SCI 5SCJ 5SCK 5SCL 5SDT 6NN4 6NN5 6NN7 6NN8 7FRV 7FRW 7FRX 7FRY 7FRZ 7FS0 7FS1 7FS2 7FS3 7FS4 7FS5 7FS6 7FS7 7FS8 7FS9 7FSA 7FSB 7FSC 7FSD 7QDN 7QZU 8TBS 8TBT 8TBU 8XFD	Homo sapiens (human)	9606	ATP binding cellular response to epinephrine stimulus cellular response to insulin stimulus cytoplasm cytosol extracellular exosome glycolytic process kinase activity magnesium ion binding monosaccharide binding phosphorylation potassium ion binding pyruvate biosynthetic process pyruvate kinase activity pyruvate kinase complex response to ATP response to cAMP response to glucose response to hypoxia response to metal ion response to nutrient	GO:0000287 GO:0001666 GO:0004743 GO:0005524 GO:0005737 GO:0005829 GO:0006096 GO:0007584 GO:0009749 GO:0010038 GO:0016301 GO:0016310 GO:0030955 GO:0032869 GO:0033198 GO:0042866 GO:0048029 GO:0051591 GO:0070062 GO:0071872 GO:1902912

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