GlyCosmos Portal

GlyCosmos Lectins

Integrated list of Lectins, including proteins with carbohydrate binding function obtained from UniProt and lectin data from Lectin Frontier DataBase (LfDB), UniLectin and CarboGrove. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Source	Last Updated
MCAW	July 10, 2019
UniLectin	June 14, 2023
UniProt	June 6, 2024
Lectin Frontier DataBase (LfDB)	April 6, 2018
CarboGrove	June 14, 2023

Displaying entries **51 - 75** of **298** in total

« First

‹ Prev

1

2

3

4

5

6

7

…

Next ›

Last »
GlyCosmos Lectin	Lectin Name	UniProt ID	PDB IDs	Organism	Taxonomy ID	Gene Ontology	Gene Ontology ID ▲
GL_001835	Sorbitol dehydrogenase	Q00796	1PL6 1PL7 1PL8	Homo sapiens (human)	9606	(R,R)-butanediol dehydrogenase activity D-sorbitol dehydrogenase (acceptor) activity D-xylulose reductase activity L-iditol 2-dehydrogenase activity L-xylitol catabolic process L-xylitol metabolic process NAD binding carbohydrate binding cytosol extracellular exosome extracellular space flagellated sperm motility fructose biosynthetic process glucose metabolic process glucuronate catabolic process to xylulose 5-phosphate identical protein binding membrane mitochondrial membrane motile cilium ribitol 2-dehydrogenase activity sorbitol catabolic process zinc ion binding	GO:0000721 GO:0003939 GO:0005615 GO:0005829 GO:0006006 GO:0006062 GO:0008270 GO:0016020 GO:0019640 GO:0030246 GO:0030317 GO:0031514 GO:0031966 GO:0042802 GO:0046370 GO:0046526 GO:0047833 GO:0050255 GO:0051160 GO:0051164 GO:0051287 GO:0070062
GL_000990	Protein OS-9	Q13438	3AIH	Homo sapiens (human)	9606	ERAD pathway Hrd1p ubiquitin ligase complex carbohydrate binding endoplasmic reticulum lumen endoplasmic reticulum membrane endoplasmic reticulum unfolded protein response endoplasmic reticulum negative regulation of retrograde protein transport, ER to cytosol protease binding protein retention in ER lumen protein targeting protein ubiquitination response to endoplasmic reticulum stress retrograde protein transport, ER to cytosol ubiquitin-dependent protein catabolic process	GO:0000836 GO:0002020 GO:0005783 GO:0005788 GO:0005789 GO:0006511 GO:0006605 GO:0006621 GO:0016567 GO:0030246 GO:0030968 GO:0030970 GO:0034976 GO:0036503 GO:1904153
GL_003444	Alpha-protein kinase 1	Q96QP1	5Z2C	Homo sapiens (human)	9606	ATP binding centrosome cilium assembly cilium cytoplasmic pattern recognition receptor signaling pathway cytosol innate immune response monosaccharide binding phosphorylation positive regulation of canonical NF-kappaB signal transduction protein serine kinase activity protein serine/threonine kinase activity spindle pole	GO:0000922 GO:0002753 GO:0004674 GO:0005524 GO:0005813 GO:0005829 GO:0005929 GO:0016310 GO:0043123 GO:0045087 GO:0048029 GO:0060271 GO:0106310
GL_000169	C-type lectin domain family 3 member A	O75596		Homo sapiens (human)	9606	carbohydrate binding extracellular space ossification skeletal system development	GO:0001501 GO:0001503 GO:0005615 GO:0030246
GL_001169	Versican core protein	P13611		Homo sapiens (human)	9606	Golgi lumen calcium ion binding carbohydrate binding cell adhesion cell recognition central nervous system development collagen-containing extracellular matrix endoplasmic reticulum lumen extracellular matrix structural constituent conferring compression resistance extracellular matrix extracellular region extracellular space glial cell differentiation glial cell migration glycosaminoglycan binding hyaluronic acid binding interphotoreceptor matrix lysosomal lumen membrane osteoblast differentiation perineuronal net photoreceptor outer segment positive regulation of neuroblast proliferation skeletal system development synapse	GO:0001501 GO:0001649 GO:0001750 GO:0002052 GO:0005509 GO:0005539 GO:0005540 GO:0005576 GO:0005615 GO:0005788 GO:0005796 GO:0007155 GO:0007417 GO:0008037 GO:0008347 GO:0010001 GO:0016020 GO:0030021 GO:0030246 GO:0031012 GO:0033165 GO:0043202 GO:0045202 GO:0062023 GO:0072534
GL_000051	Aggrecan core protein	P16112	4MD4 7RDV	Homo sapiens (human)	9606	Golgi lumen carbohydrate binding cell adhesion central nervous system development collagen-containing extracellular matrix extracellular matrix structural constituent extracellular region extracellular space glial cell differentiation hyaluronic acid binding lysosomal lumen metal ion binding perineuronal net positive regulation of neuroblast proliferation proteolysis skeletal system development synapse	GO:0001501 GO:0002052 GO:0005201 GO:0005540 GO:0005576 GO:0005615 GO:0005796 GO:0006508 GO:0007155 GO:0007417 GO:0010001 GO:0030246 GO:0043202 GO:0045202 GO:0046872 GO:0062023 GO:0072534
GL_000807	Neurocan core protein	O14594		Homo sapiens (human)	9606	Golgi lumen calcium ion binding carbohydrate binding cell adhesion central nervous system development extracellular region extracellular space glial cell differentiation hyaluronic acid binding lysosomal lumen perineuronal net positive regulation of neuroblast proliferation skeletal system development synapse	GO:0001501 GO:0002052 GO:0005509 GO:0005540 GO:0005576 GO:0005615 GO:0005796 GO:0007155 GO:0007417 GO:0010001 GO:0030246 GO:0043202 GO:0045202 GO:0072534
GL_000109	Brevican core protein	Q96GW7		Homo sapiens (human)	9606	Golgi lumen carbohydrate binding cell adhesion central nervous system development extracellular region extracellular space glial cell differentiation glutamatergic synapse hippocampus development hyaluronic acid binding lysosomal lumen perineuronal net positive regulation of neuroblast proliferation side of membrane skeletal system development synapse maturation synapse	GO:0001501 GO:0002052 GO:0005540 GO:0005576 GO:0005615 GO:0005796 GO:0007155 GO:0007417 GO:0010001 GO:0021766 GO:0030246 GO:0043202 GO:0045202 GO:0060074 GO:0072534 GO:0098552 GO:0098978
GL_004706	Putative inactive beta-glucuronidase-like protein SMA3	Q15486		Homo sapiens (human)	9606	beta-glucuronidase activity carbohydrate binding extracellular space glucuronoside catabolic process nervous system development signaling receptor binding skeletal system development	GO:0001501 GO:0004566 GO:0005102 GO:0005615 GO:0007399 GO:0019391 GO:0030246
GL_001143	Tetranectin	P05452	1HTN 1RJH 1TN3 3L9J	Homo sapiens (human)	9606	bone mineralization calcium ion binding carbohydrate binding cellular response to organic substance cellular response to transforming growth factor beta stimulus collagen-containing extracellular matrix cytoplasm extracellular exosome extracellular region extracellular space granular component heparin binding kringle domain binding ossification platelet dense granule lumen positive regulation of plasminogen activation	GO:0001503 GO:0001652 GO:0005509 GO:0005576 GO:0005615 GO:0005737 GO:0008201 GO:0010756 GO:0030246 GO:0030282 GO:0031089 GO:0036143 GO:0062023 GO:0070062 GO:0071310 GO:0071560
GL_000140	C-type lectin domain family 11 member A	Q9Y240		Homo sapiens (human)	9606	carbohydrate binding cytoplasm extracellular region extracellular space growth factor activity ossification positive regulation of cell population proliferation	GO:0001503 GO:0005576 GO:0005615 GO:0005737 GO:0008083 GO:0008284 GO:0030246
GL_001829	Sclerostin	Q9BQB4	2K8P 3SOV 6L6R	Homo sapiens (human)	9606	BMP binding BMP signaling pathway DNA-binding transcription factor binding Golgi apparatus canonical Wnt signaling pathway carbohydrate binding cellular response to parathyroid hormone stimulus extracellular region extracellular space heparin binding localization molecular function inhibitor activity negative regulation of BMP signaling pathway negative regulation of Wnt signaling pathway negative regulation of canonical Wnt signaling pathway negative regulation of ossification negative regulation of protein-containing complex assembly ossification positive regulation of DNA-templated transcription protein-containing complex response to mechanical stimulus	GO:0001503 GO:0005576 GO:0005615 GO:0005794 GO:0008201 GO:0009612 GO:0030178 GO:0030246 GO:0030279 GO:0030509 GO:0030514 GO:0031333 GO:0032991 GO:0036122 GO:0045893 GO:0051179 GO:0060070 GO:0071374 GO:0090090 GO:0140297 GO:0140678
GL_005165	Peptidyl-glycine alpha-amidating monooxygenase	P19021		Homo sapiens (human)	9606	L-ascorbic acid binding calcium ion binding copper ion binding extracellular exosome extracellular region fatty acid primary amide biosynthetic process membrane peptide amidation peptidylamidoglycolate lyase activity peptidylglycine monooxygenase activity response to zinc ion secretory granule membrane transport vesicle membrane zinc ion binding	GO:0001519 GO:0004504 GO:0004598 GO:0005507 GO:0005509 GO:0005576 GO:0008270 GO:0010043 GO:0016020 GO:0030658 GO:0030667 GO:0031418 GO:0062112 GO:0070062
GL_000551	Inactive cell surface hyaluronidase CEMIP2	Q9UHN6	8C6I	Homo sapiens (human)	9606	angiogenesis cadherin binding calcium ion binding carbohydrate binding cytosol extracellular exosome hyaluronan catabolic process intracellular membrane-bounded organelle membrane nucleolus plasma membrane regulation of sprouting angiogenesis	GO:0001525 GO:0005509 GO:0005730 GO:0005829 GO:0005886 GO:0016020 GO:0030214 GO:0030246 GO:0043231 GO:0045296 GO:0070062 GO:1903670
GL_002047	P-selectin	P16109	1FSB 1G1Q 1G1R 1G1S 1HES	Homo sapiens (human)	9606	calcium ion binding calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules calcium-dependent protein binding calcium-mediated signaling using intracellular calcium source cell adhesion cell-cell adhesion defense response to Gram-negative bacterium external side of plasma membrane extracellular space fucose binding glycosphingolipid binding heparin binding heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules inflammatory response integrin binding leukocyte cell-cell adhesion leukocyte tethering or rolling lipopolysaccharide binding oligosaccharide binding plasma membrane platelet alpha granule membrane platelet dense granule membrane positive regulation of leukocyte migration positive regulation of leukocyte tethering or rolling positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of platelet activation regulation of integrin activation response to cytokine response to lipopolysaccharide sialic acid binding	GO:0001530 GO:0002687 GO:0005178 GO:0005509 GO:0005615 GO:0005886 GO:0006954 GO:0007155 GO:0007157 GO:0007159 GO:0008201 GO:0009897 GO:0010572 GO:0016339 GO:0031088 GO:0031092 GO:0032496 GO:0033623 GO:0033691 GO:0034097 GO:0035584 GO:0042806 GO:0043208 GO:0048306 GO:0050829 GO:0050901 GO:0051897 GO:0070492 GO:0098609 GO:1903238
GL_001669	Keratin, type II cytoskeletal 1	P04264	4ZRY 6E2J 6UUI	Homo sapiens (human)	9606	blood microparticle carbohydrate binding collagen-containing extracellular matrix complement activation, lectin pathway cornified envelope cytoplasm cytoskeleton cytosol establishment of skin barrier extracellular exosome extracellular region extracellular space fibrinolysis ficolin-1-rich granule lumen intermediate filament organization keratin filament keratinization membrane negative regulation of inflammatory response nucleus peptide cross-linking protein heterodimerization activity protein heterotetramerization regulation of angiogenesis response to oxidative stress signaling receptor activity structural constituent of skin epidermis	GO:0001533 GO:0001867 GO:0005576 GO:0005615 GO:0005634 GO:0005737 GO:0005829 GO:0005856 GO:0006979 GO:0016020 GO:0018149 GO:0030246 GO:0030280 GO:0031424 GO:0038023 GO:0042730 GO:0045095 GO:0045109 GO:0045765 GO:0046982 GO:0050728 GO:0051290 GO:0061436 GO:0062023 GO:0070062 GO:0072562 GO:1904813
GL_000373	F-box only protein 2	Q9UK22		Homo sapiens (human)	9606	ERAD pathway SCF ubiquitin ligase complex SCF-dependent proteasomal ubiquitin-dependent protein catabolic process amyloid-beta binding carbohydrate binding cytoplasm cytosol denatured protein binding dendritic spine endoplasmic reticulum extrinsic component of postsynaptic membrane glutamatergic synapse glycoprotein catabolic process negative regulation of cell population proliferation protein modification process protein ubiquitination proteolysis regulation of protein catabolic process at postsynapse, modulating synaptic transmission regulation of protein ubiquitination ubiquitin protein ligase activity ubiquitin-protein transferase activity	GO:0001540 GO:0004842 GO:0005737 GO:0005783 GO:0005829 GO:0006508 GO:0006516 GO:0008285 GO:0016567 GO:0019005 GO:0030246 GO:0031146 GO:0031249 GO:0031396 GO:0036211 GO:0036503 GO:0043197 GO:0061630 GO:0098890 GO:0098978 GO:0099576
GL_002359	Pentraxin-related protein PTX3	P26022	7ZL1	Homo sapiens (human)	9606	(1->3)-beta-D-glucan binding complement component C1q complex binding extracellular matrix organization extracellular matrix extracellular region extracellular space identical protein binding inflammatory response innate immune response negative regulation by host of viral exo-alpha-sialidase activity negative regulation by host of viral glycoprotein metabolic process negative regulation by host of viral process negative regulation of exo-alpha-sialidase activity negative regulation of glycoprotein metabolic process negative regulation of viral entry into host cell opsonization ovarian cumulus expansion positive regulation of nitric oxide biosynthetic process positive regulation of phagocytosis response to yeast specific granule lumen tertiary granule lumen virion binding	GO:0001550 GO:0001849 GO:0001872 GO:0001878 GO:0005576 GO:0005615 GO:0006954 GO:0008228 GO:0030198 GO:0031012 GO:0035580 GO:0042802 GO:0044793 GO:0044869 GO:0044871 GO:0045087 GO:0045429 GO:0046597 GO:0046790 GO:0050766 GO:1903016 GO:1903019 GO:1904724
GL_002356	Tenascin	P24821	1TEN 2RB8 2RBL 5R5T 5R5U 5R5V 5R5W 5R5X 5R5Y 5R5Z 5R60 5R61 5R62 5R63 6BRB 6QNV 8FN8 8FNB	Homo sapiens (human)	9606	basement membrane bud outgrowth involved in lung branching cell adhesion cellular response to prostaglandin D stimulus cellular response to retinoic acid cellular response to vitamin D collagen-containing extracellular matrix endoplasmic reticulum lumen extracellular matrix structural constituent extracellular region extracellular space focal adhesion integrin binding interstitial matrix membrane mesenchymal-epithelial cell signaling involved in prostate gland development morphogenesis of an epithelium negative regulation of cell adhesion neuromuscular junction development odontogenesis of dentin-containing tooth osteoblast differentiation peripheral nervous system axon regeneration perisynaptic extracellular matrix positive regulation of cell population proliferation positive regulation of gene expression prostate gland epithelium morphogenesis regulation of cell adhesion regulation of cell growth regulation of cell migration regulation of inflammatory response response to ethanol response to fibroblast growth factor response to mechanical stimulus response to wounding syndecan binding tenascin complex	GO:0001558 GO:0001649 GO:0002009 GO:0005178 GO:0005201 GO:0005576 GO:0005604 GO:0005614 GO:0005615 GO:0005788 GO:0005925 GO:0007155 GO:0007162 GO:0007528 GO:0008284 GO:0009611 GO:0009612 GO:0010628 GO:0014012 GO:0016020 GO:0030155 GO:0030334 GO:0042475 GO:0045471 GO:0045545 GO:0050727 GO:0060447 GO:0060739 GO:0060740 GO:0062023 GO:0071300 GO:0071305 GO:0071774 GO:0071799 GO:0090733 GO:0098966
GL_005016	Prolyl hydroxylase EGLN2	Q96KS0	5V1B	Homo sapiens (human)	9606	2-oxoglutarate-dependent dioxygenase activity L-ascorbic acid binding cell redox homeostasis cellular response to hypoxia cytoplasm ferrous iron binding hypoxia-inducible factor-proline dioxygenase activity intracellular estrogen receptor signaling pathway nucleoplasm nucleus oxygen sensor activity peptidyl-proline 4-dioxygenase activity peptidyl-proline hydroxylation to 4-hydroxy-L-proline positive regulation of protein catabolic process regulation of cell growth regulation of neuron apoptotic process response to hypoxia	GO:0001558 GO:0001666 GO:0005634 GO:0005654 GO:0005737 GO:0008198 GO:0016706 GO:0018401 GO:0019826 GO:0030520 GO:0031418 GO:0031545 GO:0043523 GO:0045454 GO:0045732 GO:0071456 GO:0160082
GL_005069	Phytanoyl-CoA dioxygenase, peroxisomal	O14832	2A1X	Homo sapiens (human)	9606	2-oxobutyrate catabolic process 2-oxoglutarate metabolic process 9+0 non-motile cilium L-ascorbic acid binding carboxylic acid binding cytosol fatty acid alpha-oxidation ferrous iron binding isoprenoid metabolic process methyl-branched fatty acid metabolic process peroxisomal matrix peroxisome phytanoyl-CoA dioxygenase activity	GO:0001561 GO:0005777 GO:0005782 GO:0005829 GO:0006103 GO:0006720 GO:0008198 GO:0019606 GO:0031406 GO:0031418 GO:0048244 GO:0097089 GO:0097731
GL_000880	Polycystin-1-like protein 3	Q7Z443		Homo sapiens (human)	9606	calcium channel activity carbohydrate binding cation channel complex cellular response to acidic pH detection of chemical stimulus involved in sensory perception of sour taste detection of mechanical stimulus extracellular exosome kidney development membrane monoatomic cation transport plasma membrane receptor complex sensory perception of sour taste	GO:0001581 GO:0001822 GO:0005262 GO:0005886 GO:0006812 GO:0016020 GO:0030246 GO:0034703 GO:0043235 GO:0050915 GO:0050982 GO:0070062 GO:0071468
GL_002375	Coxsackievirus and adenovirus receptor	P78310	1EAJ 1F5W 1JEW 1KAC 1P69 1P6A 1RSF 2J12 2J1K 2NPL 2W9L 2WBW 3J6L 3J6M 3J6N 3J6O 7DPZ 7DQ1 7VXZ 7VYK 7VYL 7VYM 7W14	Homo sapiens (human)	9606	AV node cell to bundle of His cell communication AV node cell-bundle of His cell adhesion involved in cell communication PDZ domain binding acrosomal vesicle actin cytoskeleton organization adherens junction apicolateral plasma membrane basolateral plasma membrane beta-catenin binding bicellular tight junction cardiac muscle cell development cell adhesion molecule binding cell adhesive protein binding involved in AV node cell-bundle of His cell communication cell body cell junction cell-cell junction organization cell-cell junction connexin binding cytoplasm defense response to virus epithelial structure maintenance extracellular region extracellular space filopodium gamma-delta T cell activation germ cell migration growth cone heart development heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules homotypic cell-cell adhesion identical protein binding integrin binding intercalated disc membrane raft mitochondrion organization neuromuscular junction neuron projection neutrophil chemotaxis nucleoplasm plasma membrane protein-containing complex regulation of AV node cell action potential signaling receptor binding transepithelial transport virus receptor activity	GO:0001618 GO:0001669 GO:0005102 GO:0005178 GO:0005576 GO:0005615 GO:0005654 GO:0005737 GO:0005886 GO:0005911 GO:0005912 GO:0005923 GO:0007005 GO:0007157 GO:0007507 GO:0008013 GO:0008354 GO:0010669 GO:0014704 GO:0016323 GO:0016327 GO:0030036 GO:0030054 GO:0030165 GO:0030175 GO:0030426 GO:0030593 GO:0031594 GO:0032991 GO:0034109 GO:0042802 GO:0043005 GO:0044297 GO:0045121 GO:0045216 GO:0046629 GO:0050839 GO:0051607 GO:0055013 GO:0070633 GO:0071253 GO:0086067 GO:0086072 GO:0086082 GO:0098904
GL_002323	Intercellular adhesion molecule 1	P05362	1D3E 1D3I 1D3L 1IAM 1IC1 1MQ8 1P53 1Z7Z 2OZ4 3TCX 5MZA 6EIT 6S8U 7BG7	Homo sapiens (human)	9606	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell T cell antigen processing and presentation T cell extravasation adhesion of symbiont to host cell adhesion mediated by integrin cell adhesion cell surface cellular response to amyloid-beta cellular response to glucose stimulus cellular response to leukemia inhibitory factor collagen-containing extracellular matrix establishment of endothelial barrier external side of plasma membrane extracellular exosome extracellular space focal adhesion heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules immunological synapse integrin binding leukocyte cell-cell adhesion leukocyte migration membrane raft membrane to membrane docking membrane negative regulation of endothelial cell apoptotic process negative regulation of extrinsic apoptotic signaling pathway via death domain receptors plasma membrane positive regulation of ERK1 and ERK2 cascade positive regulation of cellular extravasation receptor-mediated virion attachment to host cell regulation of leukocyte mediated cytotoxicity regulation of ruffle assembly signaling receptor activity transmembrane signaling receptor activity virus receptor activity	GO:0001618 GO:0001772 GO:0001910 GO:0002291 GO:0002457 GO:0002693 GO:0004888 GO:0005178 GO:0005615 GO:0005886 GO:0005925 GO:0007155 GO:0007157 GO:0007159 GO:0009897 GO:0009986 GO:0016020 GO:0022614 GO:0033627 GO:0038023 GO:0044406 GO:0045121 GO:0046813 GO:0050900 GO:0061028 GO:0062023 GO:0070062 GO:0070374 GO:0071333 GO:0072683 GO:1900027 GO:1902042 GO:1904646 GO:1990830 GO:2000352
GL_000190	C-type lectin domain family 5 member A	Q9NY25	2YHF	Homo sapiens (human)	9606	carbohydrate binding cell surface cellular defense response cytosol innate immune response myeloid cell differentiation negative regulation of apoptotic process negative regulation of myeloid cell apoptotic process osteoblast development plasma membrane positive regulation of cytokine production signal transduction specific granule membrane tertiary granule membrane virus receptor activity	GO:0001618 GO:0001819 GO:0002076 GO:0005829 GO:0005886 GO:0006968 GO:0007165 GO:0009986 GO:0030099 GO:0030246 GO:0033033 GO:0035579 GO:0043066 GO:0045087 GO:0070821

Download data in CSV format Download data in TSV format Download data in JSON format

Table Filtering

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

International Collaboration

Acknowledgements