GlyCosmos Portal

GlyCosmos Lectins

Integrated list of Lectins, including proteins with carbohydrate binding function obtained from UniProt and lectin data from Lectin Frontier DataBase (LfDB), UniLectin and CarboGrove. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Source	Last Updated
MCAW	July 10, 2019
UniLectin	June 14, 2023
UniProt	June 6, 2024
Lectin Frontier DataBase (LfDB)	April 6, 2018
CarboGrove	June 14, 2023

Displaying entries **1 - 25** of **298** in total

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GlyCosmos Lectin	Lectin Name	UniProt ID	PDB IDs	LfDB IDs	Monosaccharide Specificities	Organism	Taxonomy ID	MCAW IDs	Gene Ontology	Gene Ontology ID ▼
GL_000534	Grifin	A4D1Z8				Homo sapiens (human)	9606		carbohydrate binding	GO:0030246
GL_000519	Galectin-related protein	Q3ZCW2	2JJ6 3B9C			Homo sapiens (human)	9606		carbohydrate binding	GO:0030246
GL_001029	Putative C-type lectin domain family 20 member A	Q6ZU45				Homo sapiens (human)	9606		carbohydrate binding	GO:0030246
GL_000487	Galectin-2 Aliases: Galectin-2 (Human)	P05162	1HLC 5DG1 5DG2 5EWS	LfDB0055	Gal	Homo sapiens (human)	9606	5110	T cell homeostasis carbohydrate binding cell-cell adhesion galactoside binding galectin complex positive regulation of apoptotic process positive regulation of inflammatory response	GO:0016936 GO:0030246 GO:0043029 GO:0043065 GO:0050729 GO:0098609 GO:1990724
GL_000631	Killer cell lectin-like receptor subfamily G member 2	A4D1S0				Homo sapiens (human)	9606		carbohydrate binding membrane	GO:0016020 GO:0030246
GL_000166	C-type lectin domain family 2 member L	P0C7M8				Homo sapiens (human)	9606		carbohydrate binding membrane	GO:0016020 GO:0030246
GL_000555	Integral membrane protein DGCR2/IDD	P98153				Homo sapiens (human)	9606		animal organ morphogenesis carbohydrate binding cell adhesion cognition membrane	GO:0007155 GO:0009887 GO:0016020 GO:0030246 GO:0050890
GL_002018	Galectin-16	A8MUM7	6LJP 6LJQ 6LJR			Homo sapiens (human)	9606		apoptotic process carbohydrate binding collagen-containing extracellular matrix lactose binding positive regulation of T cell apoptotic process	GO:0006915 GO:0030246 GO:0030395 GO:0062023 GO:0070234
GL_000185	C-type lectin domain family 4 member F	Q8N1N0				Homo sapiens (human)	9606		carbohydrate binding endocytosis external side of plasma membrane	GO:0006897 GO:0009897 GO:0030246
GL_000299	CD302 antigen	Q8IX05	2NAN			Homo sapiens (human)	9606		carbohydrate binding cell cortex external side of plasma membrane filopodium membrane microvillus phagocytosis signaling receptor activity	GO:0005902 GO:0005938 GO:0006909 GO:0009897 GO:0016020 GO:0030175 GO:0030246 GO:0038023
GL_002428	Sialic acid-binding Ig-like lectin 15	Q6ZMC9	7ZOZ			Homo sapiens (human)	9606		plasma membrane protein-containing complex regulation of actin cytoskeleton organization regulation of bone resorption regulation of osteoclast development	GO:0005886 GO:0032956 GO:0032991 GO:0045124 GO:2001204
GL_001036	Putative C-type lectin-like domain family 1	Q8IZS7				Homo sapiens (human)	9606		B cell adhesion carbohydrate binding plasma membrane positive regulation of T cell proliferation positive regulation of interleukin-4 production	GO:0005886 GO:0030246 GO:0032753 GO:0042102 GO:0097323
GL_000152	C-type lectin domain family 2 member B	Q92478				Homo sapiens (human)	9606		carbohydrate binding external side of plasma membrane identical protein binding plasma membrane	GO:0005886 GO:0009897 GO:0030246 GO:0042802
GL_000151	C-type lectin domain family 2 member A	Q6UVW9	4IOP			Homo sapiens (human)	9606		carbohydrate binding external side of plasma membrane natural killer cell mediated cytotoxicity plasma membrane protein homodimerization activity	GO:0005886 GO:0009897 GO:0030246 GO:0042267 GO:0042803
GL_002410	Paired immunoglobulin-like type 2 receptor beta	Q9UKJ0	4NFC 4NFD			Homo sapiens (human)	9606		MHC class I protein binding activation of transmembrane receptor protein tyrosine kinase activity plasma membrane transmembrane receptor protein tyrosine kinase signaling pathway	GO:0005886 GO:0007169 GO:0007171 GO:0042288
GL_002411	Paired immunoglobulin-like type 2 receptor alpha	Q9UKJ1	3WUZ 3WV0 4NFB 5XO2 5XOF			Homo sapiens (human)	9606		MHC class I protein binding extracellular exosome plasma membrane signal transduction	GO:0005886 GO:0007165 GO:0042288 GO:0070062
GL_002299	Neural cell adhesion molecule 2	O15394	2DOC 2JLL 2KBG 2V5T 2VAJ 2WIM 2XY1 2XY2 2XYC			Homo sapiens (human)	9606		axon axonal fasciculation identical protein binding membrane neuron cell-cell adhesion nuclear body plasma membrane	GO:0005886 GO:0007158 GO:0007413 GO:0016020 GO:0016604 GO:0030424 GO:0042802
GL_001114	Sialic acid-binding Ig-like lectin 12	Q96PQ1				Homo sapiens (human)	9606		carbohydrate binding cell adhesion plasma membrane sialic acid binding	GO:0005886 GO:0007155 GO:0030246 GO:0033691
GL_001117	Sialic acid-binding Ig-like lectin 14	Q08ET2				Homo sapiens (human)	9606		carbohydrate binding cell adhesion ficolin-1-rich granule membrane plasma membrane sialic acid binding tertiary granule membrane	GO:0005886 GO:0007155 GO:0030246 GO:0033691 GO:0070821 GO:0101003
GL_001121	Sialic acid-binding Ig-like lectin 7	Q9Y286	1NKO 1O7S 1O7V 2DF3 2G5R 2HRL			Homo sapiens (human)	9606	1976 5378 5388	carbohydrate binding cell adhesion plasma membrane sialic acid binding signaling receptor activity	GO:0005886 GO:0007155 GO:0030246 GO:0033691 GO:0038023
GL_001118	Sialic acid-binding Ig-like lectin 16	A6NMB1				Homo sapiens (human)	9606		carbohydrate binding cell adhesion plasma membrane positive regulation of defense response to bacterium positive regulation of interleukin-6 production sialic acid binding	GO:0005886 GO:0007155 GO:0030246 GO:0032755 GO:0033691 GO:1900426
GL_001119	Sialic acid-binding Ig-like lectin 5	O15389	2ZG1 2ZG2 2ZG3			Homo sapiens (human)	9606		carbohydrate binding cell adhesion ficolin-1-rich granule membrane plasma membrane secretory granule membrane sialic acid binding tertiary granule membrane	GO:0005886 GO:0007155 GO:0030246 GO:0030667 GO:0033691 GO:0070821 GO:0101003
GL_001113	Sialic acid-binding Ig-like lectin 11	Q96RL6				Homo sapiens (human)	9606		carbohydrate binding cell adhesion phosphatase binding plasma membrane sialic acid binding	GO:0005886 GO:0007155 GO:0019902 GO:0030246 GO:0033691
GL_001415	Contactin-1	Q12860	2EE2 3S97			Homo sapiens (human)	9606		Notch signaling pathway axon guidance axon brain development carbohydrate binding cell adhesion cell-cell adhesion mediator activity cell-cell adhesion central nervous system myelin formation cerebellum development extracellular exosome gene expression locomotory behavior membrane plasma membrane positive regulation of gene expression positive regulation of neuron projection development positive regulation of sodium ion transport postsynaptic membrane presynaptic membrane side of membrane	GO:0005886 GO:0007155 GO:0007219 GO:0007411 GO:0007420 GO:0007626 GO:0010467 GO:0010628 GO:0010765 GO:0010976 GO:0016020 GO:0021549 GO:0030246 GO:0030424 GO:0032289 GO:0042734 GO:0045211 GO:0070062 GO:0098552 GO:0098609 GO:0098632
GL_001123	Sialic acid-binding Ig-like lectin 9	Q9Y336				Homo sapiens (human)	9606		carbohydrate binding cell adhesion cell surface receptor signaling pathway plasma membrane secretory granule membrane sialic acid binding	GO:0005886 GO:0007155 GO:0007166 GO:0030246 GO:0030667 GO:0033691

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