Regulation of necroptotic cell death
|
|
|
- 7tmk1
- DDB_G0267514
- DDB_G0272254
- DDB_G0275145
- DDB_G0278075
- DDB_G0278981
- DDB_G0288147
- DDB_G0288683
- DDB_G0289043
- DpyK1
- DpyK2
- DpyK4
- drkA
- drkB
- drkC
- pyK1
- pyk2
- pyk4
- pykA
- pykB
- qkgA-1
- qkgA-2
- rbrA
- rk1
- rk2
- rk3
- roco11
- roco2-1
- roco2-2
- roco4
- roco5
- roco7
- roco8
- splA
- splB
- ubqB
- ubqC
- ubqF
- ubqG
- ubqH
- ubqI
- ubqJ
- ubqO
- veg116
- vsk1
- zak1
- zak2
- zakA
|
|
Neutrophil degranulation
|
|
|
- ADA2
- Arc15
- Arp1
- CP2
- CP3
- CP4
- CP5
- CP6
- CP7
- CatD
- DDB_G0267590
- DDB_G0267742
- DDB_G0267752
- DDB_G0267952
- DDB_G0267974
- DDB_G0268034
- DDB_G0269380
- DDB_G0269774
- DDB_G0270134
- DDB_G0270454
- DDB_G0271242
- DDB_G0272220
- DDB_G0272434
- DDB_G0272742
- DDB_G0273095
- DDB_G0273153
- DDB_G0273419
- DDB_G0273473
- DDB_G0274339
- DDB_G0274461
- DDB_G0274833
- DDB_G0275535
- DDB_G0275917
- DDB_G0276227
- DDB_G0276567
- DDB_G0276661
- DDB_G0276961
- DDB_G0277093
- DDB_G0277773
- DDB_G0277967
- DDB_G0278295
- DDB_G0278401
- DDB_G0278487
- DDB_G0278563
- DDB_G0278773
- DDB_G0279493
- DDB_G0279583
- DDB_G0279675
- DDB_G0280557
- DDB_G0280565
- DDB_G0280643
- DDB_G0280855
- DDB_G0281053
- DDB_G0281055
- DDB_G0281325
- DDB_G0281401
- DDB_G0281675
- DDB_G0282107
- DDB_G0282109
- DDB_G0282177
- DDB_G0282179
- DDB_G0282517
- DDB_G0282683
- DDB_G0282859
- DDB_G0282971
- DDB_G0282991
- DDB_G0283893
- DDB_G0284155
- DDB_G0284307
- DDB_G0284753
- DDB_G0284755
- DDB_G0284997
- DDB_G0285063
- DDB_G0285639
- DDB_G0285709
- DDB_G0285897
- DDB_G0286315
- DDB_G0286691
- DDB_G0286891
- DDB_G0287185
- DDB_G0287559
- DDB_G0287731
- DDB_G0288717
- DDB_G0288795
- DDB_G0288847
- DDB_G0289029
- DDB_G0289063
- DDB_G0289195
- DDB_G0289231
- DDB_G0289735
- DDB_G0289749
- DDB_G0290593
- DDB_G0290995
- DDB_G0291131
- DDB_G0291332
- DDB_G0291524
- DDB_G0291984
- DDB_G0292160
- DDB_G0293674
- DDB_G0293678
- DDB_G0294569
- DDB_G0294571
- DDB_G0294577
- DDB_G0295811
- DDB_G0295845
- DG1029
- Rab1C
- abcA2
- abcA3
- abcA4
- abcA5
- abcA6
- abp1-1
- abp1-2
- abpA
- abpD
- abpE-1
- abpE-2
- acly
- actnA
- actnB
- actr10
- actr11
- agl
- akt
- alad
- alfA
- amdA
- ann7
- ap2a1-1
- ap2a1-2
- apg7
- apm1
- arcE
- arl8
- arlE
- armc8
- arp10
- arp11
- arp2
- arpA
- arpB
- arpH
- atg7
- atp6v1d
- calA
- calB
- camA
- cand1
- cap
- cat
- catA
- cct2
- cct8
- cda
- cdc7
- cdcD
- cdk9-1
- cdk9-2
- cf60
- cfaD
- comG
- commd3
- copb
- cpiA
- cpiB
- cpiC
- cpl
- cplA
- cpnA
- cpnB-1
- cpnB-2
- cpnC
- cpnD
- cpnE
- cpnF
- cprB
- cprC
- cprD
- cprE
- cprF
- cprG
- csnk2b
- cspA
- ctl2
- ctnC
- ctsB
- ctsD
- ctsZ
- cyb5r1
- dagA
- ddi
- ddiA
- ddost
- ddx3
- desA
- dgat1
- dhcA
- dlcA
- dlcB
- dnajc13
- dnajc3
- docA
- docB
- docC
- docD
- dst2
- dstB
- dync1li1
- eef1a1
- eef1a2
- efaAI
- efaAII
- efaa1
- efaa2
- efbA
- erk1
- erkA
- fba
- fip-1
- fip-2
- g6pi
- gaa
- gacJJ
- gapA
- gghB
- gip17
- glb1
- glpD
- glpV
- gmfA
- gmsA
- gnrA
- gnrB
- gnrC
- gpi
- gpmA
- gsta1
- gsta2-1
- gsta2-2
- gsta3
- gsta4
- gsta5
- gtr3
- guaB
- guk
- hemB
- hexb2
- hsc70
- hsc90
- hsp90
- hspB
- hspD
- hspE-1
- hspE-2
- idhM
- impdh
- ku70
- ku80
- lipA
- lkhA
- lmpA
- lmpB
- lmpC
- lvsC
- manA
- mapbpip
- melA
- mlcD
- mvpA
- nap1
- napA
- naprt
- ncstn
- ndkA
- ndkB
- ndkC-1
- ndkC-2
- ndkM
- nhp6
- nit2
- noxA
- noxB
- noxC
- nramp
- nramp1
- nxnA
- nxnB
- orfR1062
- ost3
- ost48
- p2xA
- p2xB
- p2xC
- p2xD
- p2xE
- pgam
- pgi
- pgmA
- pgmB
- pir121
- pirA
- pkbA
- pld1
- pldA
- pldB
- pldC
- poxA
- prdx4
- prlA
- psaA
- psaB
- psenA
- psenB
- psmA2
- psmA5
- psmB7
- psmC2
- psmC3
- psmD1
- psmD11
- psmD12
- psmD13
- psmD14
- psmD2
- psmD3
- psmD6
- psmD7
- ptp1
- ptp2
- ptp3
- ptpA1-1
- ptpA1-2
- ptpB
- ptpC
- pyk
- pykA
- qpct
- rab14
- rab18
- rab24
- rab32D
- rab4
- rab5A
- rab6
- rab7
- rab7A
- rab7B
- rab8A
- rab8B
- rabD
- rabK1
- rabK2
- rabK3
- rabL
- rabM
- rabN1
- rabN2
- rabR
- rabT1
- rabT2
- rabV
- rabX
- rabZ
- rac1A
- rac1B
- rac1C
- racB
- racC
- racD
- racE
- racF1
- racF2
- racH
- racI
- racJ
- racL
- racM
- racN
- racO
- racP
- racQ
- rap1
- rapA
- rapB
- rapC
- rasGAP1
- rcdC
- rgaA
- sapA
- sas1
- sas2
- sasA
- sasB
- sevA
- sks1
- slc11a1
- slc44a2
- spiA
- srp14-1
- srp14-2
- sybA
- sybB
- symA
- tctel1
- trappc1-1
- trappc1-2
- tubB
- vatM
- vatP
- veg125
- vilA
- vilB
- vilD
- ypel
|
|
Surfactant metabolism
|
|
|
- ADA2
- CatD
- DDB_G0284339
- abcA2
- abcA3
- abcA4
- abcA5
- abcA6
- ctsD
- sapA
|
|
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
|
|
|
- AurB
- Aurora
- DDB_G0272951
- M4
- aurK
- cul2
- culB
- dapA
- dpr1
- fp21A
- fp21B
- fpa1
- fpa1A
- fpa1B
- fpa2
- fpaA
- fpaB-1
- fpaB-2
- prdD
- prdE
- prtC
- prtD
- psmA1
- psmA2
- psmA3
- psmA4
- psmA5
- psmA6
- psmA7
- psmB2
- psmB3
- psmB4-1
- psmB4-2
- psmB5
- psmB6
- psmB7
- psmC1
- psmC2
- psmC3
- psmC4
- psmC6
- psmD1
- psmD10
- psmD11
- psmD12
- psmD13
- psmD14
- psmD2
- psmD3
- psmD4
- psmD6
- psmD7
- psmD8-1
- psmD8-2
- psmD9
- psmE3
- psmE4
- psmF1
- rbx1
- skp1A
- skp1B
- sks1
- tbp2
- tbpB
- ubqB
- ubqC
- ubqF
- ubqG
- ubqH
- ubqI
- ubqJ
- ubqO
- veg116
|
|
MHC class II antigen presentation
|
|
|
- CP1
- CP2
- CP3
- CP4
- CP5
- CP6
- CP7
- CatD
- DDB_G0272742
- DDB_G0274385
- DDB_G0278401
- DDB_G0282991
- DDB_G0286055
- DDB_G0291191
- cfaD
- cprA
- cprB
- cprC
- cprD
- cprE
- cprF
- cprG
- ctsB
- ctsD
- gmsA
|
|
Platelet degranulation
|
|
|
- CP1
- DDB_G0267974
- DDB_G0268156
- DDB_G0268758
- DDB_G0269600
- DDB_G0272218
- DDB_G0274385
- DDB_G0275765
- DDB_G0276317
- DDB_G0280565
- DDB_G0281889
- DDB_G0282287
- DDB_G0282859
- DDB_G0282977
- DDB_G0283859
- DDB_G0284679
- DDB_G0286055
- DDB_G0287201
- DDB_G0288133
- DDB_G0291191
- abcC1
- abcC13
- abcC14
- abcC15
- abcC2
- abcC6
- abcC7
- abcC9
- abpA
- abpC
- abpD
- act26
- actnA
- actnB
- aip1
- ann7
- calA
- calB
- camA
- chid1
- cprA
- cyb5r1
- cyri
- fam49
- fba
- fip-1
- fip-2
- gtpbp1
- lmpA
- lmpB
- lmpC
- mlcD
- nxnA
- nxnB
- rab32D
- sadA
- sapA
- scfd2
- sec1
- sec1A
- sodE
- talB
- triA
- tubA
- vti1
- vti1A
- vti1B
- wdpA
|
|
Degradation of the extracellular matrix
|
|
|
- CP2
- CP3
- CP4
- CP5
- CP6
- CP7
- DDB_G0272742
- DDB_G0278401
- DDB_G0282991
- cfaD
- cprB
- cprC
- cprD
- cprE
- cprF
- cprG
|
|
Aspirin ADME
|
|
|
- D2
- DDB_G0268184
- DDB_G0276969
- DDB_G0279717
- DDB_G0285555
- DDB_G0291344
- abcC10
- abcC12
- abcC3
- abcC5
- abcC8
- cryS
- cyp508A1-1
- cyp508A1-2
- cyp508A2-1
- cyp508A2-2
- cyp508A3-1
- cyp508A3-2
- cyp508A4
- cyp508B1
- cyp508C1
- cyp508D1
- cyp515A1
- cyp515B1
- cyp516A1
- cyp516B1
- cyp517A1
- cyp517A2
- cyp517A4
- cyp518A1
- cyp518B1
- cyp519B1
- cyp519D1
- cyp519E1
- cyp521A1
- cyp522A1
- cyp554A1
- cyp555A1
- ostA
- ostB
- ugt2
- ugt3
|
|
Phase I - Functionalization of compounds
|
|
|
- D2
- DDB_G0270652
- DDB_G0275953
- DDB_G0276969
- DDB_G0277999
- DDB_G0279717
- DDB_G0283819
- DDB_G0285555
- DDB_G0288165
- DDB_G0291344
- comG
- cryS
- cyb5B
- cyb5C
- cyb5r1
- cyp508A1-1
- cyp508A1-2
- cyp508A2-1
- cyp508A2-2
- cyp508A3-1
- cyp508A3-2
- cyp508A4
- cyp508B1
- cyp508C1
- cyp508D1
- cyp515A1
- cyp515B1
- cyp516A1
- cyp516B1
- cyp517A1
- cyp517A2
- cyp517A4
- cyp518A1
- cyp518B1
- cyp519B1
- cyp519D1
- cyp519E1
- cyp521A1
- cyp522A1
- cyp554A1
- cyp555A1
- ostA
- ostB
|
|
Synthesis of PC
|
|
|
- D2
- DDB_G0271730
- DDB_G0276969
- DDB_G0279717
- DDB_G0282159
- DDB_G0285555
- DDB_G0288717
- DDB_G0290229
- DDB_G0291344
- DG1056
- abhd
- captA
- captB
- captC
- captD
- cryS
- ctl2
- lipB
- pemtA
- slc44a2
|
|
Metabolism of Angiotensinogen to Angiotensins
|
|
|
- D2
- DDB_G0276969
- DDB_G0279717
- DDB_G0285555
- DDB_G0291344
- cryS
|
|
Neurotransmitter clearance
|
|
|
- D2
- DDB_G0276969
- DDB_G0279717
- DDB_G0285555
- DDB_G0291344
- cryS
|
|
Physiological factors
|
|
|
- D2
- DDB_G0276969
- DDB_G0279717
- DDB_G0285555
- DDB_G0291344
- cryS
|
|
Negative regulation of MAPK pathway
|
|
|
- DDB_G0267566
- DDB_G0267686
- DDB_G0268876
- DDB_G0270200
- DDB_G0271350
- DDB_G0271860
- DDB_G0272092
- DDB_G0273199
- DDB_G0282963
- DDB_G0290471
- DDB_G0291516
- DDB_G0291664
- DDB_G0292880
- RacGEF
- erk1
- erkA
- kxcB
- mpl1
- mpl2
- mpl3
- mrkC
- phg2
- ptp1
- ptp2
- ptp3
- ptpA1-1
- ptpA1-2
- ptpB
- ptpC
- spkA-1
- spkA-2
|
|
RAF activation
|
|
|
- DDB_G0267566
- DDB_G0267686
- DDB_G0268876
- DDB_G0272092
- DDB_G0282963
- DDB_G0290471
- DDB_G0291516
- DDB_G0291664
- RacGEF
- kxcB
- mrkC
- phg2
- spkA-1
- spkA-2
|
|
Clathrin-mediated endocytosis
|
|
|
- DDB_G0267588
- DDB_G0271676
- DDB_G0271812
- DDB_G0272638
- DDB_G0274261
- DDB_G0274695
- DDB_G0279059
- DDB_G0279493
- DDB_G0280377
- DDB_G0281155
- DDB_G0281235
- DDB_G0286115
- DDB_G0286699
- DDB_G0292190
- DDB_G0292610
- PIPkinA
- abcC1
- abcC13
- abcC14
- abcC15
- abcC2
- abcC6
- abcC7
- abcC9
- ap1b1
- ap2a1-1
- ap2a1-2
- ap2s1
- apm1
- apm2
- apmA
- chcA
- clc
- clcA
- clmA
- eps15
- gacBB
- lmpC
- mgp1
- mrrA
- pik1
- pik2
- pik3
- pikA
- pikB
- pikC
- pikF
- pikG
- pikH
- sybA
- sybB
|
|
Regulation of PTEN stability and activity
|
|
|
- DDB_G0267906
- DDB_G0272951
- DDB_G0275865
- DDB_G0281657
- DDB_G0283983
- DDB_G0285063
- DDB_G0285967
- DDB_G0286481
- DDB_G0288795
- DDB_G0292920
- M4
- akt
- casK
- cnrN
- csnk2b
- dagA
- dapA
- dpr1
- pkbA
- prdD
- prdE
- prtC
- prtD
- psmA1
- psmA2
- psmA3
- psmA4
- psmA5
- psmA6
- psmA7
- psmB2
- psmB3
- psmB4-1
- psmB4-2
- psmB5
- psmB6
- psmB7
- psmC1
- psmC2
- psmC3
- psmC4
- psmC6
- psmD1
- psmD10
- psmD11
- psmD12
- psmD13
- psmD14
- psmD2
- psmD3
- psmD4
- psmD6
- psmD7
- psmD8-1
- psmD8-2
- psmD9
- psmE3
- psmE4
- psmF1
- pteN
- ptenA
- sks1
- tbp2
- tbpB
- ubpA
- ubqB
- ubqC
- ubqF
- ubqG
- ubqH
- ubqI
- ubqJ
- ubqO
- usp5
- veg116
|
|
Peroxisomal protein import
|
|
|
- DDB_G0268018
- DDB_G0274339
- DDB_G0275415
- DDB_G0277335
- DDB_G0277477
- DDB_G0279049
- DDB_G0280851
- DDB_G0282495
- DDB_G0287851
- DDB_G0290089
- DDB_G0290277
- DDB_G0290547
- acox1
- agxt
- cat
- catA
- ddo-1
- ddo-2
- ech1
- hacl1
- haox
- hmgL
- idhM
- mfe2
- mfeB
- pex10
- pex12
- pex13
- pex14
- pex5
- pex7
- redB
- ubcB
- ubqB
- ubqC
- ubqF
- ubqG
- ubqH
- ubqI
- ubqJ
- ubqO
- veg116
|
|
COPII-mediated vesicle transport
|
|
|
- DDB_G0268044
- DDB_G0268452
- DDB_G0269584
- DDB_G0269942
- DDB_G0270566
- DDB_G0271968
- DDB_G0274803
- DDB_G0275331
- DDB_G0276935
- DDB_G0281693
- DDB_G0282433
- DDB_G0283055
- DDB_G0286167
- DDB_G0291694
- DDB_G0293712
- cak1-1
- cak1-2
- cnrM
- ctsZ
- gmsA
- grpA
- nsfA
- ppp6c
- pppD
- rab1A
- rab1B
- rab1D
- rab1E
- rabA
- rabF1-1
- rabF1-2
- rabS
- rabU
- rabW
- rabY
- rsmM
- sarA
- scfd1
- sec13
- sec23
- sec24
- sec24l
- sec31
- snpA
- snpC
- syn5
- syn7
- syn7A
- tmem1-1
- tmem1-2
- trapcc10-1
- trapcc10-2
- trappc1-1
- trappc1-2
- trappc2
- trappc2l
- trappc3
- trappc4
- trappc5
- wimA
|
|
Cargo recognition for clathrin-mediated endocytosis
|
|
|
- DDB_G0268156
- DDB_G0274261
- DDB_G0279059
- DDB_G0279493
- DDB_G0281155
- DDB_G0286699
- DDB_G0292610
- abcC1
- abcC13
- abcC14
- abcC15
- abcC2
- abcC6
- abcC7
- abcC9
- ap1b1
- ap2a1-1
- ap2a1-2
- ap2s1
- apm1
- apm2
- apmA
- clmA
- csn1
- csn2
- csn3
- csn4
- csn5
- csn6
- csn7
- csn8
- epnA
- eps15
- lmpC
- mrrA
- nedd8
- sonA
- sybA
- sybB
- ubqln
|
|
Prednisone ADME
|
|
|
- DDB_G0268184
- DDB_G0268562
- abcB2
- abcB3
- abcB6
- abcB7
- alrA
- alrB
- alrC
- tagA
- tagB
- tagC
- tagD
- ugt2
- ugt3
|
|
Atorvastatin ADME
|
|
|
- DDB_G0268184
- abcB2
- abcB3
- abcB6
- abcB7
- abcC10
- abcC12
- abcC3
- abcC5
- abcC8
- tagA
- tagB
- tagC
- tagD
- ugt2
- ugt3
|
|
Cargo concentration in the ER
|
|
|
- DDB_G0268452
- DDB_G0269942
- DDB_G0271968
- ctsZ
- gmsA
- sarA
- sec23
- sec24
- sec24l
- syn5
|
|
Antigen processing: Ubiquitination & Proteasome degradation
|
|
|
- DDB_G0268504
- DDB_G0269704
- DDB_G0270000
- DDB_G0271372
- DDB_G0271726
- DDB_G0271956
- DDB_G0272202
- DDB_G0272218
- DDB_G0272951
- DDB_G0273381
- DDB_G0273419
- DDB_G0273451
- DDB_G0273573
- DDB_G0274897
- DDB_G0275145
- DDB_G0277011
- DDB_G0277047
- DDB_G0277053
- DDB_G0277075
- DDB_G0277249
- DDB_G0277429
- DDB_G0278049
- DDB_G0278075
- DDB_G0278671
- DDB_G0278981
- DDB_G0279003
- DDB_G0279093
- DDB_G0279435
- DDB_G0279463
- DDB_G0280089
- DDB_G0280091
- DDB_G0280347
- DDB_G0280581
- DDB_G0280895
- DDB_G0281369
- DDB_G0281657
- DDB_G0281679
- DDB_G0281833
- DDB_G0282391
- DDB_G0282479
- DDB_G0283667
- DDB_G0283893
- DDB_G0283983
- DDB_G0284145
- DDB_G0284325
- DDB_G0285063
- DDB_G0285261
- DDB_G0285581
- DDB_G0285797
- DDB_G0286289
- DDB_G0286387
- DDB_G0286991
- DDB_G0287221
- DDB_G0288345
- DDB_G0288683
- DDB_G0289043
- DDB_G0289099
- DDB_G0290547
- DDB_G0290641
- DDB_G0291131
- DDB_G0291612
- DDB_G0291902
- DDB_G0291984
- DDB_G0292144
- DDB_G0292302
- DDB_G0292362
- DDB_G0292586
- DDB_G0293756
- DDB_G0295713
- M4
- anapc1
- anapc10
- anapc11
- anapc2
- anapc3
- anapc4
- anapc5
- anapc6
- anapc7
- anapc8
- apc1
- apc10
- apc11
- apc2
- apc3
- apc4
- apc5
- apc6
- apc7
- apc8
- apg7
- atg7
- cblA-1
- cblA-2
- cdc16
- cdc20
- cdc23
- cdc26
- cdc27
- cdh1
- cnrM
- cul1
- cul2
- cul3
- cul5
- culA
- culB
- culC
- culE
- dapA
- dpr1
- fp21A
- fp21B
- fpa1
- fpa1A
- fpa1B
- fpa2
- fpaA
- fpaB-1
- fpaB-2
- gacGG
- hbx1
- mip1-1
- mip1-2
- mtpn
- nosA
- prdD
- prdE
- prtC
- prtD
- psaA
- psaB
- psmA1
- psmA2
- psmA3
- psmA4
- psmA5
- psmA6
- psmA7
- psmB2
- psmB3
- psmB4-1
- psmB4-2
- psmB5
- psmB6
- psmB7
- psmC1
- psmC2
- psmC3
- psmC4
- psmC6
- psmD1
- psmD10
- psmD11
- psmD12
- psmD13
- psmD14
- psmD2
- psmD3
- psmD4
- psmD6
- psmD7
- psmD8-1
- psmD8-2
- psmD9
- psmE3
- psmE4
- psmF1
- rbrA
- rbx1
- rnf160
- skp1A
- skp1B
- sks1
- tbp2
- tbpB
- tceb1
- tirA
- triA
- uae1
- uba1
- uba3
- uba5
- ubc2
- ubcB
- ubcC
- ubch10
- ube1c
- ube2c
- ube2j2
- ube2m
- ube2n
- ube2s
- ube2v
- ube2w
- ube3a
- ubqB
- ubqC
- ubqF
- ubqG
- ubqH
- ubqI
- ubqJ
- ubqO
- veg116
- warA
- wri
|
|
N-glycan trimming in the ER and Calnexin/Calreticulin cycle
|
|
|
- DDB_G0268520
- ubqB
- ubqC
- ubqF
- ubqG
- ubqH
- ubqI
- ubqJ
- ubqO
- veg116
|
|