Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Database | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence ▼ | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
|
Unknown
|
Sialic acid (α2,6)
|
Saccharides
|
Most organs including the central nervous system/heart/liver
|
NeuAc(a2-6)
|
Binding
|
||
|
Unknown
|
NeuAcα2-3GalNAcβ1-4GlcNAc
|
Oligosaccharides
|
NeuAc(a2-3)GalNAc(b1-4)GlcNAc
|
Binding
|
|||
|
Viral protein
|
NeuAcα2,3-Gal/GalNAc side chains of MAA-binding glycoproteins
|
Glycoproteins
|
Feline kidney(CRFK)/Equine fetal kidney(EFK)/Mouse(McCoy)/Rabbit kidney(RK-13)
|
NeuAc(a2-3)Gal/GalNAc
|
Binding
|
||
|
Unknown
|
Sialyl-dimeric Lewis x (SdiLex-HSA)
|
Glycoproteins
|
Human serum albumin
|
NeuAc(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(c)-APD
|
Binding
|
||
|
SabA (sialic acid-binding adhesin)
|
Sialyl-dimeric Lewis x (SdiLex) (GSL)
|
Monosialoglycosphingolipids
|
NeuAc(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
|||
|
Unknown
|
Sialyl Lewis x (SLex-HSA)
|
Glycoproteins
|
Human serum albumin
|
NeuAc(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(c)-APD
|
Binding
|
||
|
Unknown
|
NeuAc-SLex (GSL) (Sialylneolactofucopentaosylcer)
|
Monosialoglycosphingolipids
|
Human colon adenocarcinoma cells (WiDr )
|
NeuAc(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer
|
Not Binding
|
||
|
Unknown
|
NeuAc-SLex (GSL) (Sialylneolactofucopentaosylcer)
|
Monosialoglycosphingolipids
|
NeuAc(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
|||
|
Unknown
|
Sialyl Lewis x (SLex) antigen (d18:1,18:0)
|
Oligosaccharides
|
NeuAc(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b
|
Binding
|
|||
|
Neutrophil-activating proteins (150-kDa)
|
I-active ganglioside
|
Sialoglycosphingolipids
|
Human placenta
|
NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-6)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer
|
Not Binding
|
Displaying entries 91 - 100 of 1840 in total
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International Collaboration
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Acknowledgements
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
