GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source	Glycan Sequence	Binding ▲	PubMed ID
Entamoeba histolytica	Raft-like plasma membrane domains	Galactose	Monosaccharides	Intestinal cells	Gal	Binding	15322032
Pseudomonas aeruginosa	Unknown	Fucose	Monosaccharides	Respiratory tract	Fuc	Binding	16564136
Pasteurella haemolytica	68-kDa proteins	N-Acetylglucosamine	Monosaccharides	Bronchial lavages of sheep with pneumonic pasteurelosis	GlcNAc	Binding	10570221
Salmonella typhimurium	Unknown	Mannose	Monosaccharides	Intestinal cells	Man	Binding	16564136
Vibrio cholerae	MSHA (mannose/glucose-specific hemagglutinin)	Mannose	Monosaccharides	Patient with acute watery diarrhea	Man	Binding	10219594
Vibrio cholerae	MSHA (mannose/glucose-specific hemagglutinin)	Glucose	Monosaccharides	Patient with acute watery diarrhea	Glc	Binding	10219594
Escherichia coli	PrsG (class III)	Gb4 (Globoside; Globotetraose; P antigen)	Oligoglycosylceramides	Human erythrocytes	GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	9673272
Escherichia coli	PrsG (class III) G adhesins	Gb5 (Forssman glycolipid)	Oligoglycosylceramides	Acute cystitis patients	GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Binding
Escherichia coli	PapG (class I)	Gb4 (Globoside; Globotetraose; P antigen)	Oligoglycosylceramides	Human erythrocytes	GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	9673272
Burkholderia cepacia	Lectin-like proteins (adhesin)	Asialo-GM2 (Gangliotriosylceramide; GgO3)	Oligoglycosylceramides	Sputa of cystic fibrosis patients	GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	8606110