GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule ▲	Ligand Name	Ligand Feature	Target Source	Glycan Sequence	Binding	PubMed ID
Streptococcus suis	Adhesins	P1 antigen (GSL)	Glycosphingolipids		Gal(a1-4)Gal	Binding	7961660
Streptococcus pneumoniae	Adhesins	Asialo-GM2 (Gangliotriosylceramide; GgO3)	Oligoglycosylceramides		GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	2115881
Streptococcus pneumoniae	Adhesins	nLc4Cer (Neolactotetraosylceramide; Paragloboside)	Oligoglycosylceramides		Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Binding	2115881
Pseudomonas aeruginosa	Adhesins	Asialo-GM2 (Gangliotriosylceramide; GgO3)	Oligoglycosylceramides		GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	2115881
Pseudomonas aeruginosa	Adhesins	nLc4Cer (Neolactotetraosylceramide; Paragloboside)	Oligoglycosylceramides		Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Binding	2115881
Haemophilus influenzae	Adhesins	Asialo-GM2 (Gangliotriosylceramide; GgO3)	Oligoglycosylceramides		GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	2115881
Haemophilus influenzae	Adhesins	nLc4Cer (Neolactotetraosylceramide; Paragloboside)	Oligoglycosylceramides		Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Binding	2115881
Streptococcus gordonii	Adhesins	PMN (polymorphonuclear leukocytes) surface glycoproteins in the presence of sialic acid	Glycoproteins	Human peripheral blood buffy coat cells		Binding	11035744
Helicobacter pylori	Adhesins	Five-sugar monosialoganglioside	Monosialoglycosphingolipids	Human leukocytes, Human neutrophils		Binding	10569742
Actinomyces naeslundii	Adhesins	PMN (polymorphonuclear leukocytes) surface glycoproteins	Glycoproteins	Human peripheral blood buffy coat cells		Binding	11035744