GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule ▲	Ligand Name	Ligand Feature	Target Source	Glycan Sequence	Binding	PubMed ID
Actinomyces naeslundii	Adhesins	Asialofetuin	Glycoproteins	HL-60 promyelocytic leukemia cell line		Binding	11035744
Shigella dysenteriae	Adhesins	Colonic mucin	Glycoproteins	Colon		Binding	11381327
Helicobacter pylori	Adhesins	Fetuin	Glycoproteins	Human leukocytes, Human neutrophils		Binding	10569742
Pseudomonas aeruginosa	Adhesins	MUC1 mucin	Glycoproteins	Surface of chinese hamster ovary (CHO) cells		Binding	11133508
Mycoplasma pneumoniae	Adhesins	Fetuin	Glycoproteins	Bovine erythrocytes		Binding	2470754
Streptococcus gordonii	Adhesins	Fetuin	Glycoproteins	HL-60 promyelocytic leukemia cell line		Binding	11035744
Cryptococcus neoformans	Adhesins	Sucrose	Monosaccharides	Human lung epithelial cell line (A549)		Binding	9453390
Cryptococcus neoformans	Adhesins	Inositol	Non-glycosylated Lipids	Human lung epithelial cell line (A549)		Binding	9453390
Helicobacter pylori	Adhesins	Blood group Lewis b (Leb) antigen	Oligosaccharides			Binding	8018146
Legionella pneumophila	Adhesins	GD1a	Disialoglycosphingolipids	Human epithelial cells (respiratory tract)	NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Not Binding	14687561