GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source ▲	Glycan Sequence	Binding	PubMed ID
Neisseria meningitidis	OpcA	Sialic acid-containing polysaccharides	Polysaccharides	Epithelial cells		Binding	18076035
Foot-and-mouth disease virus	RGD motif of the VP1 GH loop	αvβ6 Integrin	Glycoproteins	Epithelial cells		Binding	10799568
Pseudomonas aeruginosa	Flagellin	MUC1 mucin	Glycoproteins	Epithelial cells		Binding	11880301
Pseudomonas aeruginosa	exoenzyme S	Phosphatidylethanolamine (PE)	Non-glycosylated Lipids	Epithelial cells		Binding	9224879
Pseudomonas aeruginosa	Type 4-pili	Lactosylceramide (Lactocerebroside)	Diosylceramides	Epithelial cells	Gal(b1-4)Glc(b1-1)Cer	Binding	9224879
Pseudomonas aeruginosa	Type 4-pili	Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)	Oligoglycosylceramides	Epithelial cells	Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	9224879
Pseudomonas aeruginosa	Type 4-pili	Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)	Oligoglycosylceramides	Epithelial cells	Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	9224879
Pseudomonas aeruginosa	exoenzyme S	Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)	Oligoglycosylceramides	Epithelial cells	Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	9224879
Pseudomonas aeruginosa	Flagellin	Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)	Oligoglycosylceramides	Epithelial cells	Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	9224879
Pseudomonas aeruginosa	LPS	Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)	Oligoglycosylceramides	Epithelial cells	Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	9224879