GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source	Glycan Sequence ▲	Binding	PubMed ID
Escherichia coli	Unknown	isoGb3 (Isoglobotriaosylceramide; iGb3)	Oligoglycosylceramides		Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	2435422
Shigella dysenteriae	Unknown	isoGb3 (Isoglobotriaosylceramide; iGb3)	Oligoglycosylceramides		Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	2435422
Propionibacterium freudenreichii	Unknown	isoGb3 (Isoglobotriaosylceramide; iGb3)	Oligoglycosylceramides		Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	2435422
Clostridium difficile	Toxin A	unnamed ligand	Oligosaccharides	Human colonic cells	Gal(a1-3)Gal(b1-4)GlcNAc	Binding	12507507
Clostridium difficile	C-terminal domain of toxin A molecules	unnamed ligand	Oligosaccharides	Human colonic cells	Gal(a1-3)Gal(b1-4)GlcNAc	Binding	12507507
Mycoplasma pneumoniae	Unknown	Alpha-Galactosyl paragloboside	Oligoglycosylceramides	Human colon adenocarcinoma cells (WiDr )	Gal(a1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Binding	2470753
Escherichia coli	F1C	Alpha-Galactosyl paragloboside	Oligoglycosylceramides	Rabbit erythrocytes	Gal(a1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	11877427
Lactobacillus johnsonii	Unknown	Alpha-Galactosyl paragloboside	Oligoglycosylceramides	Rabbit erythrocytes	Gal(a1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	11087711
Shigella dysenteriae	B subunit	Alpha-Galactosyl paragloboside	Oligoglycosylceramides	Rabbit erythrocytes	Gal(a1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	3543013
Rotavirus	Unknown	Alpha-Galactosyl paragloboside	Oligoglycosylceramides		Gal(a1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	11160731