GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature ▼	Target Source	Glycan Sequence	Binding	PubMed ID
Cytomegalovirus	Unknown	NeuAc3-nLc6Cer (Sialyl neolactohexaosylceramide)	Sialoglycosphingolipids		NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	9780061
Influenza virus	Unknown	NeuAc3-nLc6Cer (Sialyl neolactohexaosylceramide)	Sialoglycosphingolipids		NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	7870741
Influenza virus	Unknown	NeuAc3-nLc6Cer (Sialyl neolactohexaosylceramide)	Sialoglycosphingolipids		NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Binding	7870741
Helicobacter pylori	Unknown	NeuAc3-nLc6Cer (Sialyl neolactohexaosylceramide)	Sialoglycosphingolipids		NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Binding	9169796
Polyoma virus	Capsid VP1	GD1a-GT1b analog	Sialoglycosphingolipids	(broad range)		Binding	18809496
Reovirus	Unknown	Sialic acid (α2,6)	Saccharides	Most organs including the central nervous system/heart/liver	NeuAc(a2-6)	Binding	18216114
Streptococcus pneumoniae	Adhesins	GlcNAc(b1-3)Gal sequence	Saccharides	Human endothelial cells	GlcNAc(b1-3)Gal	Binding	6886624
Actinomyces naeslundii	Type 2-fimbriae	β-linked galactosamine	Saccharides	Buccae	GalNAc(b 2:2	Binding	9712794
Actinomyces naeslundii	Type 2-fimbriae	β-linked galactosamine	Saccharides	Plaque	GalNAc(b 2:2	Binding	9712794
Actinomyces odontolyticus	Type 2-fimbriae	β-linked galactosamine	Saccharides	Buccae	GalNAc(b 2:2	Binding	9712794