GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source ▲	Glycan Sequence	Binding	PubMed ID
Escherichia coli	P-pili	Gb4 (Globoside; Globotetraose; P antigen)	Oligoglycosylceramides	Epithelial cells in human urinary tract	GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	9007266
Escherichia coli	PapG (class II)	Gb4 (Globoside; Globotetraose; P antigen)	Oligoglycosylceramides	Epithelial cells in human urinary tract	GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	9007266
Escherichia coli	P-pili	Gb2 (Galabiosylceramide)	Diosylceramides	Epithelial cells in human urinary tract	Gal(a1-4)Gal(b1-1)Cer	Binding	9007266
Escherichia coli	PapG (class II)	Gb2 (Galabiosylceramide)	Diosylceramides	Epithelial cells in human urinary tract	Gal(a1-4)Gal(b1-1)Cer	Binding	9007266
Rotavirus	VP8	Sialic acid	Monosaccharides	Epithelial cells of small intestine		Binding	16511112
Escherichia coli	SfaI-S	Sialic acid	Monosaccharides	Epithelial cells, Extracellular matrix (ECM)		Binding	10732678
Polyoma virus	Unknown	Sialylated oligosaccharides	Oligosaccharides	Erythrocytes	NeuAc(a2-3)Gal(b1-3)GalNAc	Binding	6316632
Mycoplasma pneumoniae	Adhesins	Sulfatide (CSE)	Sulfoglycosphingolipids	Erythrocytes	HSO3(-3)Gal(b1-1)Cer	Binding	2470754
Streptococcus suis	Adhesins	Gb4 (Globoside; Globotetraose; P antigen)	Oligoglycosylceramides	Erythrocytes	GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	7961660
Polyoma virus	Unknown	Sialylated oligosaccharides	Oligosaccharides	Erythrocytes	NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc	Binding	6316632