GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source	Binding	PubMed ID
Pseudomonas aeruginosa	exoenzyme S	Phosphatidylethanolamine (PE)	Non-glycosylated Lipids	Epithelial cells	Binding	9224879
Campylobacter upsaliensis	5 bacterial surface proteins (50 to 90-kDa)	Phosphatidylethanolamine (PE)	Non-glycosylated Lipids	HEp-2 cells	Binding	8926069
Campylobacter upsaliensis	Unknown	Lyso-PE	Non-glycosylated Lipids	HEp-2 cells	Binding	8926069
Clostridium botulinum	BoNT/D (two lysine residues (K1117 and K1135 in Hc/D1))	Phosphatidylethanolamine (PE)	Non-glycosylated Lipids	Presynaptic neuronal cells	Binding	18242046
Helicobacter pylori	SabA (sialic acid-binding adhesin)	Fucosylated Lewis b (Leb) histoblood group antigens	Oligosaccharides	Mucosal surface of the gastric epithelium	Binding	12640357
Norovirus	Unknown	Blood group O antigen	Oligosaccharides	Human saliva	Binding	16707048
Helicobacter pylori	BabA (blood group antigen binding adhesin)	Fucosylated Lewis b (Leb) histoblood group antigens	Oligosaccharides	Human gastric epithelium	Binding	9430586
Human immunodeficiency virus	Unknown	N-acetyl-b-maltoheptaosylamine sulfate (SM)	Oligosaccharides	Human T cells	Binding	9420059
Chlamydia trachomatis	Unknown	N-acetyl-b-maltoheptaosylamine sulfate (SM)	Oligosaccharides	HeLa cells	Binding	9420059
Herpes simplex virus	Unknown	N-acetyl-b-maltoheptaosylamine sulfate (SM)	Oligosaccharides	Human cervical cells	Binding	9420059