GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature ▲	Target Source	Glycan Sequence	Binding	PubMed ID
Helicobacter pylori	Lectin-hemagglutinin adhesins	Blood group Lewis b (Leb) antigen	Oligosaccharides			Binding	12704182
Lactobacillus johnsonii	Unknown	Blood group Lewis b (Leb) antigen	Oligosaccharides			Binding	11087711
Polyoma virus	Unknown	Sialylated oligosaccharides	Oligosaccharides	Erythrocytes	NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc	Binding	6316632
Influenza virus	Residues 226 (leucine) and 228 (serine)	Sialic acid α2,6Galβ1,4GalNAc	Oligosaccharides	Human isolates	NeuAc(a2-6)Gal(b1-4)GalNAc	Binding	7975212
Haemophilus influenzae	Unknown	Pentasaccharide	Oligosaccharides	Respiratory tract	NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc	Binding	16564136
Streptococcus pneumoniae	Unknown	Pentasaccharide	Oligosaccharides	Respiratory tract	NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc	Binding	16564136
Polyoma virus	Capsid protein VP1	Sialylated oligosaccharides	Oligosaccharides	Cell surface	NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc	Binding	8805524
Neisseria meningitidis	Unknown	Pentasaccharide	Oligosaccharides	Respiratory tract	NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc	Binding	16564136
Escherichia coli	Type 1-fimbriae	unnamed ligand	Oligosaccharides	Urine	Man(a1-3)Man(a1-6)Man	Binding	16564136
Clostridium difficile	Toxin A	unnamed ligand	Oligosaccharides	Human colonic cells	GalNAc(b1-3)Gal(b1-4)GlcNAc	Binding	12507507