Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Database | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source ▼ | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
|
PapG (class I) G adhesins
|
Gal alpha 1-4 Gal-containing isoreceptors
|
Glycosphingolipids
|
Pyelonephritis patients
|
Gal(a1-4)Gal
|
Binding
|
||
|
Unknown
|
ICAM-1 (intercellular adhesion molecule-1) domain1/2
|
Glycoproteins
|
Primary chicken embryo fibroblasts (CEFs)
|
Binding
|
|||
|
Botulinum neurotoxin (type C)
|
GD1b
|
Disialoglycosphingolipids
|
Presynaptic neuronal cells
|
Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
|
BoNT/C (located within amino acid residues 1122-1290)
|
GD1b
|
Disialoglycosphingolipids
|
Presynaptic neuronal cells
|
Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
|
Botulinum neurotoxin (type C)
|
GT1b
|
Trisialoglycosphingolipids
|
Presynaptic neuronal cells
|
NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
|
BoNT/C (located within amino acid residues 1122-1290)
|
GT1b
|
Trisialoglycosphingolipids
|
Presynaptic neuronal cells
|
NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
|
Botulinum neurotoxin (type D)
|
Phosphatidylethanolamine (PE)
|
Non-glycosylated Lipids
|
Presynaptic neuronal cells
|
Binding
|
|||
|
BoNT/D (two lysine residues (K1117 and K1135 in Hc/D1))
|
Phosphatidylethanolamine (PE)
|
Non-glycosylated Lipids
|
Presynaptic neuronal cells
|
Binding
|
|||
|
Tetanus neurotoxin
|
Polysialogangliosides and other acidic lipids
|
Glycolipids
|
Presynaptic membrane of neuromuscular junction
|
Binding
|
|||
|
TeNT
|
Polysialogangliosides and other acidic lipids
|
Glycolipids
|
Presynaptic membrane of neuromuscular junction
|
Binding
|
Displaying entries 151 - 160 of 1840 in total
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International Collaboration
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Acknowledgements
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
