GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source ▲	Binding	PubMed ID
Foot-and-mouth disease virus	Natural ligand of integrin [alpha]v[beta]3	Heparin	Glycosaminoglycans	Extracellular matrix (ECM)	Binding	8764038
Foot-and-mouth disease virus	VP1 (RGD peptide)	Heparan sulfate (independent of expression of αvβ3 Integrin on cell-sulface)	Glycosaminoglycans	Extracellular matrix (ECM)	Binding	9557639
Foot-and-mouth disease virus	VP1 (RGD peptide)	Heparan sulfate (independent of expression of αvβ3 Integrin on cell-sulface)	Glycosaminoglycans	Extracellular matrix (ECM)	Binding	9557639
Foot-and-mouth disease virus	VP1 (RGD peptide)	Heparan sulfate (independent of expression of αvβ3 Integrin on cell-sulface)	Glycosaminoglycans	Extracellular matrix (ECM)	Binding	9557639
Foot-and-mouth disease virus	VP1 (RGD peptide)	Heparan sulfate (independent of expression of αvβ3 Integrin on cell-sulface)	Glycosaminoglycans	Extracellular matrix (ECM)	Binding	9557639
Foot-and-mouth disease virus	Natural ligand of integrin [alpha]v[beta]3	Chondroitin sulfate A	Glycosaminoglycans	Extracellular matrix (ECM)	Not Binding	8764038
Foot-and-mouth disease virus	Natural ligand of integrin [alpha]v[beta]3	Chondroitin sulfate C	Glycosaminoglycans	Extracellular matrix (ECM)	Not Binding	8764038
Sporothrix schenckii	Yeast cells and conidia	Fibronectin	Glycoproteins	Extracellular matrix (ECM)	Binding	11598061
Leptospira interrogans	Lsa24	Laminin	Glycoproteins	Extracellular matrix (ECM)	Binding	16954400
Sporothrix schenckii	Yeast cells and hyphae	Fibronectin	Glycoproteins	Extracellular matrix (ECM)	Binding	15351036