GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source	Glycan Sequence ▲	Binding	PubMed ID
Norovirus	Unknown	Blood group B antigen	Oligosaccharides		Gal(a1-3)[Fuc(a1-2)]Gal	Binding	18599458
Streptococcus pneumoniae	FcsSBP (fucose solute-binding protein)	Blood group B antigen	Oligosaccharides		Gal(a1-3)[Fuc(a1-2)]Gal	Binding	19285508
Norovirus	Unknown	Blood group B antigen (B-tri-HSA)	Glycoproteins	Human serum albumin	Gal(a1-3)[Fuc(a1-2)]Gal(b)-O-APE	Binding	19054801
Norovirus	Unknown	Blood group B antigen (B-tri-HSA)	Glycoproteins		Gal(a1-3)[Fuc(a1-2)]Gal(b)-O-APE	Binding	18701592
Norovirus	Unknown	Blood group B antigen (B-tri-HSA)	Glycoproteins		Gal(a1-3)[Fuc(a1-2)]Gal(b)-O-APE	Not Binding	18701592
Vibrio cholerae	Cholera toxin	B-GM1	Monosialoglycosphingolipids		Gal(a1-3)[Fuc(a1-2)]Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	7527546
Vibrio cholerae	Unknown	B-GM1	Monosialoglycosphingolipids		Gal(a1-3)[Fuc(a1-2)]Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	7527546
Helicobacter pylori	BabA (blood group antigen binding adhesin)	Blood group B-Lewis b (BLeb) antigen	Oligosaccharides		Gal(a1-3)[Fuc(a1-2)]Gal(b1-3)[Fuc(a1-4)]GlcNAc	Binding	15273394
Actinomyces viscosus	Unknown	unnamed ligand	Oligoglycosylceramides	Various sources	Gal(a1-3)[Fuc(a1-2)]Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	2358461
Actinomyces naeslundii	Unknown	unnamed ligand	Oligoglycosylceramides	Various sources	Gal(a1-3)[Fuc(a1-2)]Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	2358461