GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Glycan Sequence	Binding	PubMed ID ▼
Escherichia coli	Unknown	unnamed ligand	Sialoglycosphingolipids	NeuAc(a2-6)[NeuAc(a2-3)]Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	2435422
Shigella dysenteriae	Unknown	unnamed ligand	Sialoglycosphingolipids	NeuAc(a2-6)[NeuAc(a2-3)]Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Not Binding	2435422
Shigella dysenteriae	Shiga toxin	Gb2 (Galabiosylceramide)	Diosylceramides	Gal(a1-4)Gal(b1-1)Cer	Binding	2435422
Escherichia coli	Unknown	Gb2 (Galabiosylceramide)	Diosylceramides	Gal(a1-4)Gal(b1-1)Cer	Binding	2435422
Shigella dysenteriae	Unknown	Gb2 (Galabiosylceramide)	Diosylceramides	Gal(a1-4)Gal(b1-1)Cer	Binding	2435422
Shigella dysenteriae	Shiga toxin	unnamed ligand	Glycosphingolipids	Fuc(a1-2)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Not Binding	2435422
Shigella dysenteriae	Unknown	unnamed ligand	Glycosphingolipids	Fuc(a1-2)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Not Binding	2435422
Propionibacterium freudenreichii	Unknown	Lewis a (Lea) (GSL)	Glycosphingolipids	Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	2435422
Propionibacterium granulosum	Unknown	Lewis a (Lea) (GSL)	Glycosphingolipids	Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Binding	2435422
Propionibacterium freudenreichii	Unknown	Galactosylceramide (Galactocerebroside)	Monoglycosylceramides	Gal(b1-1)Cer	Not Binding	2435422